Results 281 to 290 of about 1,294,431 (344)

Advances in the application of patient-derived xenograft models in acute leukemia resistance. [PDF]

Cancer Drug Resist
Qin R, Liang Y, Zhou F.
europepmc   +1 more source

Integrative Genomic and Transcriptomic Analysis Reveals Targetable Vulnerabilities in Angioimmunoblastic T‐Cell Lymphoma

American Journal of Hematology, EarlyView.
ABSTRACT Nodal follicular helper T‐cell (TFH) lymphoma of the angioimmunoblastic (AITL) subtype has a dismal prognosis. Using whole‐exome sequencing (n = 124), transcriptomic (n = 78), and methylation (n = 40) analysis, we identified recurrent mutations in known epigenetic drivers (TET2, DNMT3A, IDH2R172) and novel ones (TET3, KMT2D).
Alyssa Bouska, Weiwei Zhang, Sunandini Sharma, Harald Holte, Rauf A. Shah, Waseem G. Lone, Mahfuza Afroz Soma, Ruimeng Yang, Xuxiang Liu, Syed Mehmood, Ravneet Singh Chawla, Luca Vincenzo Cappelli, Danilo Fiore, Qiang Gong, Tayla B. Heavican‐Foral, Jeffrey J. Cannatella, Catalina Amador, Aiza Arif, Lynette M. Smith, Soon Thye Lim, Choon Kiat Ong, Andrew L. Feldman, Ming‐Qing Du, Anamarija M. Perry, Laurence de Leval, Timothy C. Greiner, Kai Fu, Gunhild Trøen, Daniel Vodák, Sigve Nakken, Jan Delabie, David Weinstock, Stefano Pileri, Antonella Laginestra, KyeongJin Kim, Utpal Pajvani, Julie M. Vose, Dennis D. Weisenburger, Steven M. Horwitz, Sandeep Dave, Joseph Khoury, Giorgio Inghirami, Wing C. Chan, Javeed Iqbal   +43 more
wiley   +1 more source

Adverse effects of dipyrone (Metamizole) use during pregnancy on offspring health: a systematic review and meta-analysis. [PDF]

BMC Pregnancy Childbirth
Lino GM, Ishibashi FS, Conrado GAM, Bresani-Salvi CC, Galvão PVM.   +4 more
europepmc   +1 more source

Association Between Moraxella catarrhalis and Nodular Lymphocyte‐Predominant Hodgkin Lymphoma

American Journal of Hematology, EarlyView.
ABSTRACT Nodular lymphocyte‐predominant Hodgkin Lymphoma (NLPHL) may be an antigen‐driven malignancy. Recent studies demonstrated that in NLPHL patients, lymphoma B‐cell receptor can bind proteins derived from Moraxella catarrhalis (MC) and Rothia mucilaginosa (RM). We examined whether MC and RM can be detected in NLPHL lymph nodes.
Izidore S. Lossos, Xiaoyu Jiang, Krishna Patel, Kamilia N. Moalem, Jordan Laser, Joo Y. Song, Anamarija M. Perry, Jennifer R. Chapman   +7 more
wiley   +1 more source

Survival analysis and clinical abnormalities in cats with progressive or regressive feline leukemia virus (FeLV) infection in Brazil. [PDF]

PLoS One
Biezus G, Grima de Cristo T, Flores Koehler CM, de Quadros Kaveski FY, Sarria Viana Miranda T, Ferian PE, Casagrande RA.   +6 more
europepmc   +1 more source

Systemic Mastocytosis in 910 Patients: Prognostic Contribution of the International Consensus Classification in the Context of the Mayo Alliance Prognostic System

American Journal of Hematology, EarlyView.
Overall survival data among 910 Mayo Clinic patients with systemic mastocytosis stratified by the International Consensus Classification (ICC) and the Mayo Alliance Prognostic Scoring System (MAPS). ABSTRACT The current study includes 910 patients with systemic mastocytosis (SM) seen at the Mayo Clinic from 1968 to 2024.
Fnu Aperna, Maymona G. Abdelmagid, Mahesh Kumar, Joseph H. Butterfield, Thanai Pongdee, Cecilia Y. Arana Yi, Mrinal S. Patnaik, Daniel A. Arber, Attilio Orazi, Dong Chen, Kaaren K. Reichard, Naseema Gangat, Animesh Pardanani, Ayalew Tefferi   +13 more
wiley   +1 more source

Improved survival in pediatric acute lymphoblastic leukemia through therapy intensification based on minimal residual disease and protocol-driven early response risk classification. [PDF]

Blood Res
Kim H, Yoon SH, Kang S, Koh KN, Im HJ, Chu D, Kim MY, Cho YU, Hwang SH, Jang S.   +9 more
europepmc   +1 more source

Impact of Cytogenetic Response to Therapy on Long‐Term Survival in Acute Myeloid Leukemia

American Journal of Hematology, EarlyView.
ABSTRACT Prognostication in acute myeloid leukemia (AML) relies on clinical, molecular, and cytogenetic factors. In this retrospective study, we examined the impact of different levels of cytogenetic response on overall survival (OS) and event‐free survival (EFS) in AML.
John Hanna, Emily C. Zabor, Moath Albliwi, Jessica El‐Asmar, Daniel P. Nurse, Ameed Bawwab, Hasan Abuamsha, Yomna Abu‐Farsakh, Heya Batah, Asad Rauf, Joy Nakitandwe, David S. Bosler, Akriti G. Jain, John C. Molina, Sophia Balderman, Abhay Singh, Aaron T. Gerds, Sudipto Mukherjee, Ronald M. Sobecks, Anjali S. Advani, Hetty E. Carraway, Caroline Astbury, Moaath K. Mustafa Ali   +22 more
wiley   +1 more source

The epigenetic revolution in hematology: from benchside breakthroughs to clinical transformations. [PDF]

Clin Exp Med
Abdar Esfahani M, Servatian N, Al-Athari AJH, Khafaja ESM, Rahmani Seraji H, Soleimani Samarkhazan H.   +5 more
europepmc   +1 more source

Mortality and Cancer Incidence After Exposure to Blue Asbestos in Childhood: A Further 10 Years of Follow‐Up

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Objectives The impact of early‐life exposure to asbestos on disease risk remains uncertain. Childhood exposure to blue asbestos at Wittenoom has previously been linked to the development of malignant mesothelioma and various cancers in adulthood, as well as to a greater risk of all‐cause mortality compared with the general population.
Renee N. Carey, Alison Reid, Nicholas de Klerk, Peter Cinquini, Nola Olsen, Fraser Brims, Peter Franklin   +6 more
wiley   +1 more source