Results 101 to 110 of about 4,728,853 (203)

Leukemia inhibitory factor regulates proopiomelanocortin transcription

, 1998
Leukemia inhibitory factor (LIF), a pleiotropic cytokine, is expressed in both fetal and adult pituitary tissue, and LIF immunoreactivity is found in functional human pituitary tumors.
Melmed, Shlomo, SHLOMO MELMED, DAVID W. RAY, Ray, David W., SONG‐GUANG REN, Ren, Song Guang   +5 more
core   +1 more source

Natural and semisynthetic bile acids as Leukemia Inhibitory Factor (LIF) receptor antagonists

Leukaemia Inhibitory Factor (LIF) is a pleiotropic member of interleukine (IL)-6 cytokine family,1 that regulates cell differentiation, proliferation and survival in embryo and adult cells and is involved in cancer growth and progression.
Claudia Finamore, Pasquale Rapacciuolo, Stefano Fiorucci, Cristina Di Giorgio, Valentina Sepe, Maria Chiara Monti, Bruno Catalanotti, Angela Zampella   +7 more
core  

(Nano)structured bioactive materials for the delivery of pleiotropic leukemia inhibitory factor

A citocina pleiotrópica fator inibidor de leucemia (FIL) tem demonstrado ser capaz de regular um diverso número de processos, incluindo processos inflamatórios e regenerativos. Contudo, a bioatividade da LIF é comprometida pela taxa de eliminação in vivo,
Pinho, Vanessa Tatiana
core  

Leukemia inhibitory factor maintains choline acetyltransferase expression in vivo

, 1998
FOLLOWING axotomy most medial septal neurons in the adult rat brain have dramatically reduced numbers of choline acetyltransferase (ChAT) positive neurons.
Cheema, SS, Arumugam, D, Murray, SS, Bartlett, PF   +3 more
core   +1 more source

Leukemia Inhibitory Factor (LIF) [PDF]

Science-Business eXchange, 2009
openaire   +2 more sources

Molecular dynamics simulations reveal key roles of the LIF receptor in the assembly of human LIF signaling complex

Computational and Structural Biotechnology Journal
Leukemia inhibitory factor (LIF) is a critical cytokine involved in various biological processes, including stem cell self-renewal, inflammation, and cancer progression.
Bo Gao, Hanrui Liu, Mengkai Zhu, Shun Zhang, Meiniang Wang, Yijun Ruan, Yue Zheng   +6 more
doaj   +1 more source

Leukemia Inhibitory Factor (LIF) Overexpression Increases the Angiogenic Potential of Bone Marrow Mesenchymal Stem/Stromal Cells. [PDF]

Front Cell Dev Biol, 2020
Santos GC, Silva DN, Fortuna V, Silveira BM, Orge ID, de Santana TA, Sampaio GL, Paredes BD, Ribeiro-Dos-Santos R, Soares MBP.   +9 more
europepmc   +1 more source

Abstract 1602: Leukemia inhibitory factor (LIF)-factor XIIIA mediated macrophage-stromal crosstalk in pancreatic cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy marked by a highly immunosuppressive tumor microenvironment (TME). Macrophages are known to promote immunosuppression and exhibit a profibrotic transcriptional profile with ...
Garrido, Vanessa T., Jaferi, Nishah, Nagathihalli, Nagaraj S., Nivelo, Luis A., Krishnamoorthy, Varun, Yuguang, Ban, Bianchi, Anna, Mehra, Siddharth, Jinka, Sudhakar   +8 more
core   +1 more source

Leukemia inhibitory factor (LIF) potentiates antinociception activity and inhibits tolerance induction of opioids

, 2017
Background: The efficacy of opioids typically decreases after long-term use owing to the development of tolerance. Glial activation and the upregulation of proinflammatory cytokines are related to the induction of tolerance. We investigated the effect of
Tu, H. J.;Kang, K. H.;Ho, S. Y.;Liou, H. C.;Liou, H. H.;Lin, C. P.;Fu, W. M., 劉宏輝;符文美;林至芃   +1 more
core   +1 more source

Impact of Leukemia Inhibitory Factor (LIF) in Ovarian Cancer Tumorigenesis and Chemoresistance

, 2021
Epithelial ovarian cancer (EOC) has the 3rd highest mortality to incidence ratio of all cancers, and high-grade serous ovarian carcinoma (HGSOC) is the most common form of EOC. Even with resection and aggressive chemotherapy treatment, tumors recur in 70%
Jorgensen, Megan
core   +1 more source