Results 81 to 90 of about 4,728,853 (203)

Leukemia inhibitory factor is immunomodulatory

, 2008
Leukemia inhibitory factor (LIF) is produced by infiltrating immune cells and glial cells during auto-immune and injury responses in the central nervous system (CNS). During these responses, LIF promotes survival of glial cells and neurons. While various
Carmans, Sofie, de Vries, E., Stinissen, Piet, Hendriks, Jerome J. A., Slaets, Leen, Dijkstra, C., Hellings, Niels   +6 more
core   +1 more source

Circulating granulocyte colony‐stimulating factor as a sex‐unbiased global marker of lung and colorectal cancer cachexia pre‐clinical models

Experimental Physiology, Volume 111, Issue 10, Page 4705-4721, 1 October 2026.
Abstract Cancer cachexia, affecting up to 80% of patients with advanced cancer, is characterized by metabolic and inflammatory dysregulation driven by tumour‐ and host‐derived factors. Although cytokines are central to cachexia pathogenesis, their circulating profiles and transcriptional relevance across models and sexes remain incompletely defined. We
Francielly Morena, Eleanor R. Schrems, Ana Regina Cabrera, Ruqaiza Muhyudin, Sepideh Shakeri, Stavroula Tsitkanou, Mark Viggars, Tyrone A. Washington, Nicholas P. Greene   +8 more
wiley   +1 more source

Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis [PDF]

The leukemia inhibitory factor (LIF) is member of interleukin (IL)-6 family of cytokines involved immune regulation, morphogenesis and oncogenesis. In cancer tissues, LIF binds a heterodimeric receptor (LIFR), formed by a LIFRβ subunit and glycoprotein ...
Fiorucci, Stefano, Bordoni, Martina, Bellini, Rachele, Lupia, Antonio, Marchianò, Silvia, Di Giorgio, Cristina, Urbani, Ginevra, Natalizi, Nicola, Graziosi, Luigina, Catalanotti, Bruno, Biagioli, Michele, Lachi, Ginevra, Sepe, Valentina, Distrutti, Eleonora, Donini, Annibale, Morretta, Elva, Zampella, Angela, Rapacciuolo, Pasquale, Finamore, Claudia, Chiara Monti, Maria, Moraca, Federica, Massa, Carmen   +21 more
core   +1 more source

Leukemia inhibitory factor ameliorates experimental anti-GBM Ab glomerulonephritis [PDF]

, 1996
Leukemia inhibitory factor ameliorates experimental anti-GBM Ab glomerulonephritis. Leukemia inhibitory factor (LIF) is a pleiotropic cytokine that has been identified in acute and chronic inflammatory conditions such as rheumatoid arthritis, sepsis, and
Qi, Meiying, Meiying Qi, Wariner, Grace P., Tang, Winson W., Babru Samal, Samal, Babru, Van, Gwyneth Y., Grace P. Wariner, Winson W. Tang, Gwyneth Y. Van   +9 more
core   +1 more source

ASXL1 in proinflammatory macrophages attenuates inflammatory activation and macrophage‐mediated renal tubular epithelial cell damage in acute kidney injury

Physiological Reports, Volume 14, Issue 19, October 2026.
ASXL1 in inflammatory macrophages attenuates renal tubular cell damage through coordinated histone modification of H3K27me3 and H3K4me3 in acute kidney injury. Abstract Macrophages are major contributors to inflammatory responses in acute kidney injury (AKI) and rapidly alter their gene expression through epigenetic regulation.
Yoshiyasu Ogura, Takehito Sugasawa, Masaomi Nangaku, Imari Mimura   +3 more
wiley   +1 more source

Expression of Leukemia Inhibitory Factor and Its Receptor in Preimplantation Embryos

, 2009
Expression of leukemia inhibitory factor and its receptor in preimplantation embryos. Chen HF, Shew JY, Ho HN, Hsu WL, Yang YS Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei.
CHEN, HSIN-FU;SHEW, JIN-YUH;HO, HONG-NERNG;HSU, WEI-LI;YANG, YU-SHIH, 陳信孚;許金玉;何弘能;徐維莉;楊友仕   +1 more
core   +1 more source

[Leukemia inhibitory factor (LIF)]. [PDF]

Nihon rinsho. Japanese journal of clinical medicine, 2011
Koshi, Kawakami, Yoshio, Honma
openaire   +3 more sources

Preferential Propagation of Competent SIX2+ Nephronic Progenitors by LIF/ROCKi Treatment of the Metanephric Mesenchyme

Stem Cell Reports, 2015
Understanding the mechanisms responsible for nephrogenic stem cell preservation and commitment is fundamental to harnessing the potential of the metanephric mesenchyme (MM) for nephron regeneration.
Shunsuke Tanigawa, Nirmala Sharma, Michael D. Hall, Ryuichi Nishinakamura, Alan O. Perantoni   +4 more
doaj   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Cigarette smoke exposure reduces leukemia inhibitory factor levels during respiratory syncytial viral infection

International Journal of COPD, 2019
Justin Poon,1 Michael Campos,2 Robert F Foronjy,1 Sridesh Nath,1 Gayatri Gupta,1 Christopher Railwah,1 Abdoulaye J Dabo,1 Nathalie Baumlin,3 Matthias Salathe,3 Patrick Geraghty11Division of Pulmonary & Critical Care Medicine, Department of Medicine ...
Poon J, Campos M, Foronjy RF, Nath S, Gupta G, Railwah C, Dabo AJ, Baumlin N, Salathe M, Geraghty P   +9 more
doaj