Results 31 to 40 of about 150,706 (165)

A Novel Deep Learning Segmentation and Classification Framework for Leukemia Diagnosis

open access: yesAlgorithms, 2023
Blood cancer occurs due to changes in white blood cells (WBCs). These changes are known as leukemia. Leukemia occurs mostly in children and affects their tissues or plasma. However, it could occur in adults. This disease becomes fatal and causes death if
A. Khuzaim Alzahrani   +4 more
doaj   +1 more source

Venetoclax for AML: changing the treatment paradigm

open access: yesBlood Advances, 2019
: Venetoclax is a specific B-cell lymphoma-2 (BCL-2) inhibitor that can restore activation of apoptosis in malignancies, the survival of which depends on dysregulation of this pathway.
Daniel A. Pollyea   +3 more
doaj   +1 more source

Inhibition of menin, BCL-2, and FLT3 combined with a hypomethylating agent cures NPM1/FLT3-ITD/-TKD mutant acute myeloid leukemia in a patient-derived xenograft model

open access: yesHaematologica, 2023
Bing Z. Carter   +8 more
doaj   +1 more source

Evaluating measurable residual disease in acute myeloid leukemia

open access: yesBlood Advances, 2018
: Mounting evidence indicates that the presence of measurable (“minimal”) residual disease (MRD), defined as posttherapy persistence of leukemic cells at levels below morphologic detection, is a strong, independent prognostic marker of increased risk of ...
Farhad Ravandi   +2 more
doaj   +1 more source

Pruritus as a Presenting Symptom of FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia

open access: yesJournal of Blood Medicine, 2021
Mohammad Abu-Tineh,1 Esra’a Aljaloudi,2 Mohamed A Yassin1 1Department of Oncology- Hematology and BMT Section, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar; 2Department of Family Medicine, Hamad Medical Corporation,
Abu-Tineh M, Aljaloudi E, Yassin MA
doaj  

Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

open access: yesBlood Cancer Journal, 2023
Bing Z. Carter   +15 more
doaj   +1 more source

Prevention and treatment of transformation of myeloproliferative neoplasms to acute myeloid leukemia

open access: yesHaematologica
Philadelphia-chromosome negative (Ph-neg) myeloproliferative neoplasms (MPNs) are hematopoietic stem disorders with a risk of progression to the accelerated-phase (AP) or blastphase (BP) that is influenced by clinical, pathologic, cytogenetic, and ...
Anand A. Patel, Raajit K. Rampal
doaj   +1 more source

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