Results 31 to 40 of about 15,006 (243)

Nanozyme Aptasensor Array for Predictive Sensing of Virulent and Antibiotic-Resistant Staphylococcus Aureus strains. [PDF]

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An array‐based nanozyme‐aptamer platform for rapid, colorimetric fingerprinting of Staphylococcus aureus strains is reported. By combining differential aptamer dissociation with pattern‐recognition analysis, the sensor achieves strain‐level discrimination, infers virulence, and predicts the identification of previously unencountered strains, offering a
Weerathunge P, Yazdani M, Sharma TK, Wong WKM, Joglekar MV, Hardikar AA, Rotello VM, Ramanathan R, Bansal V.   +8 more
europepmc   +2 more sources

Staphylococcus aureus Infection and Persistence in Chronic Rhinosinusitis: Focus on Leukocidin ED

Toxins, 2020
Chronic rhinosinusitis (CRS) is thought to be a multifactorial disease that includes a direct involvement of bacteria that trigger inflammation and contribute to CRS pathogenesis. Staphylococcus aureus infection and persistence is associated with chronic
D. Poddighe, L. Vangelista
semanticscholar   +1 more source

Matrine and baicalin inhibit apoptosis induced by Panton-Valentine leukocidin of Staphylococcus aureus in bovine mammary epithelial cells.

Journal of Dairy Science, 2020
It was previously thought that the Panton-Valentine leukocidin (PVL) toxin of Staphylococcus aureus (S. aureus) was not the main cause of cow mastitis. However, in recent years, detection of the gene encoding PVL has been increasing in dairy cow mastitis,
Fang Jia, Weiwu Ma, Xiangjun Zhang, Dong Wang, Xuezhang Zhou   +4 more
semanticscholar   +1 more source

Characterization of Antibiotic and Biocide Resistance Genes and Virulence Factors of Staphylococcus Species Associated with Bovine Mastitis in Rwanda [PDF]

, 2020
The present study was conducted from July to August 2018 on milk samples taken at dairy farms in the Northern Province and Kigali District of Rwanda in order to identify Staphylococcus spp. associated with bovine intramammary infection.
Antók, Fruzsina Irén, Ehling-Schulz, Monika, Ehricht, Ralf, Feßler, Andrea T., Fischer, Otto, Grunert, Tom, Keinprecht, Helga, Lepuschitz, Sarah, Loncaric, Igor, Marbach, Helene, Masengesho, Jean Claude, Mayrhofer, Rosa, Monecke, Stefan, Nyirimbuga, Vedaste, Ruppitsch, Werner, Schwarz, Stefan, Spergser, Joachim   +16 more
core   +2 more sources

Targeting leukocidin-mediated immune evasion protects mice from Staphylococcus aureus bacteremia

Journal of Experimental Medicine, 2020
Staphylococcus aureus secretes pore-forming leukocidins that kill leukocytes as part of the bacterium’s evasion strategy. Leukocidin-based vaccination results in toxin-neutralizing antibodies and toxin-specific CD4 lymphocytes that block the toxins and ...
K. Tam, K. Lacey, J. Devlin, M. Coffre, Alexis G. Sommerfield, Rita Chan, Aidan O’Malley, Sergei B Koralov, P. Loke, V. Torres   +9 more
semanticscholar   +1 more source

Staphylococcus aureus Impairs the Function of and Kills Human Dendritic Cells via the LukAB Toxin

mBio, 2019
Staphylococcus aureus is a human pathogen responsible for high morbidity and mortality worldwide. Recurrent infections with this bacterium are common, suggesting that S. aureus thwarts the development of sterilizing immunity. S. aureus strains that cause
Evelien T. M. Berends, Xuhui Zheng, Erin E. Zwack, Mickaël M. Ménager, Michael Cammer, Bo Shopsin, Victor J. Torres   +6 more
doaj   +1 more source

Staphylococcus aureus Panton‐Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria

The FASEB Journal, 2020
Panton‐Valentine Leukocidin (PVL) is a bicomponent leukotoxin produced by 3%‐10% of clinical Staphylococcus aureus (SA) strains involved in the severity of hospital and community‐acquired infections.
Viola Mazzoleni, Gaëlle Zimmermann-Meisse, A. Smirnova, I. Tarassov, G. Prévost   +4 more
semanticscholar   +1 more source

Identification of Panton-Valentine leukocidin virulence gene in methicillin—resistant Staphylococcus aureus isolated from clinical specimens of burn patients in Zare Hospitals of Sari, Iran

Journal of Acute Disease, 2020
Objective: To identify the pathogenic gene of Panton-Valentine leukocidin in methicillin-resistant Staphylococcus aureus strain isolated from clinical specimens of burn patients in Shaheed Zare Burn Hospital.
Atefeh Ranjkesh, Zahra Salari, Mehrab Nejat, Emad Behboudi, Ali Ramezani, Milad Zandi, Mahmood Marzban, Hadis Kiani, Mina Bavi, Mehdi Rabiei Roodsari, Yousef Esvand Zibaee, Samaneh Abbasi, Maryam Mohammadi Elyasi, Mehdi Parsanahad, Shahram Jalilian, Simin Mohammadi Gorji, Mina Owrang   +16 more
doaj   +1 more source

Draft Genome Sequence of a Community-Associated Methicillin- Resistant Panton-Valentine Leukocidin-Positive Staphylococcus aureus Sequence Type 30 Isolate from a Pediatric Patient with a Lung Infection in Brazil [PDF]

, 2015
The sequence of methicillin-resistant Staphylococcus aureus strain B6 (sequence type 30 [ST30], spa type t433, staphylococcal chromosomal cassette mec element [SCCmec] type IVc, Panton-Valentine leukocidin [PVL] positive), isolated from a pediatric ...
Afonso de Araujo, Veronica, Aguiar-Alves, Fábio, Araújo Cardoso, Claudete A., Cho, Paul Jang-Yeon, de Azevedo Sias, Selma Maria, Gomes, Ivete Martins, Riley, Lee W., Stephens, Craig M.   +7 more
core   +2 more sources

Prevalence and association of Panton-Valentine Leukocidin gene with the risk of sepsis in patients infected with Methicillin Resistant Staphylococcus aureus.

Journal of Infection and Public Health, 2020
BACKGROUND Panton-Valentine Leukocidin (PVL), is one of the virulence gene expressed by Methicillin Resistant Staphylococcus aureus (MRSA) and is known to be associated with severe form of community acquired MRSA infection.
Noor Ahmad, Chan Yean Yean, P. Foo, A. W. Mohamad Safiee, S. Hassan   +4 more
semanticscholar   +1 more source