PLoS ONE, 2020 Production of the Panton-Valentine leukocidin (PVL) by Staphylococcus aureus is mediated via the genes lukS-PV and lukF-PV which are carried on bacteriophage ϕSa2. PVL is associated with S.
G. Coombs +4 more
semanticscholar +1 more source
Community-associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections in a pediatric hospital in Argentina [PDF]
, 2014 Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) emerged at the Pediatric Hospital of Misiones Province, north Argentina, in 2003 as a cause of community-acquired (CA) infections, mostly associated with skin and soft tissue infections ...
Gardella, Noella Mariel +5 more
core +1 more source
New targets for leukocidins [PDF]
Nature Reviews Microbiology, 2019 This study shows that staphylococcal leukocidins target endothelial cells to cause host lethality.
openaire +2 more sources
Phenol-Soluble Modulin Toxins of Staphylococcus haemolyticus
Frontiers in Cellular and Infection Microbiology, 2017 Coagulase-negative staphylococci (CoNS) are important nosocomial pathogens and the leading cause of sepsis. The second most frequently implicated species, after Staphylococcus epidermidis, is Staphylococcus haemolyticus.
Fei Da +7 more
doaj +1 more source
Can Panton Valentine Leukocidin Gene And Clindamycin Susceptibility Serve As Predictors of Community Origin of Mrsa From Skin and Soft Tissue Infections? [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Community associated Methicillin-resistant Staphylococcus aureus (CA-MRSA) strains have begun to replace Hospital Associated MRSA (HA-MRSA) strains in hospital settings all over the world.
Nandita Shashindran +3 more
doaj +1 more source
Pathogens, 2021 Methicillin-resistant Staphylococcus aureus (MRSA) is mostly found in Thailand in the hospital as a nosocomial pathogen. This study aimed to report the genetic characterization of a clinical community-acquired MRSA (CA-MRSA) isolate collected from ...
Wichai Santimaleeworagun +3 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Background: Staphylococcus aureus is a major human pathogen. Panton-Valentine leukocidin (PVL) is a virulence factor produced by some strains that causes leukocyte lysis and tissue necrosis. PVL-associated S. aureus (PVL-SA) predominantly causes skin and
Saffiatou Darboe +18 more
semanticscholar +1 more source
INTERACTION OF BACTERIAL EXOTOXINS WITH NEUTROPHIL EXTRACELLULAR TRAPS: IMPACT FOR THE INFECTED HOST
Frontiers in Microbiology, 2016 Since their discovery in 2004, neutrophil extracellular traps (NETs) have been characterized as a fundamental host innate immune defense against various pathogens.
Maren evon Köckritz-Blickwede +3 more
doaj +1 more source
Staphylococcus aureus temperate bacteriophage: carriage and horizontal gene transfer is lineage associated. [PDF]
, 2012 Staphylococcus aureus is a major cause of human and animal infections. Bacteriophage are a class of mobile genetic element (MGE) that carry virulence genes and disseminate them horizontally, including Panton-Valentine leukocidin (PVL), the immune evasion
Lindsay, JA, McCarthy, AJ, Witney, AA
core +2 more sources
Mode of Action of Staphylococcal Leukocidin: Relationship between Binding of 125 I-Labeled S and F Components of Leukocidin to Rabbit Polymorphonuclear Leukocytes and Leukocidin Activity [PDF]
Infection and Immunity, 1981 The binding of 125 I-labeled S component to rabbit polymorphonuclear leukocytes was found to be concentration dependent and saturable at 37°C. Scatchard analysis of the binding curve gave a straight line, indicating that S component binds to a single population of sites. The dissociation constant,
M, Noda +3 more
openaire +2 more sources