Results 51 to 60 of about 15,006 (243)

S. aureus hemolysins, bi-component leukocidins and cytolytic peptides: a redundant arsenal of membrane-damaging virulence factors?

Frontiers in Cellular and Infection Microbiology, 2012
One key aspect of S. aureus virulence lies in its ability to target the host cell membrane with a large number of membrane-damaging toxins and peptides.
Francois eVandenesch, Francois eVandenesch, Francois eVandenesch, Gérard eLina, Gérard eLina, Gérard eLina, Thomas eHenry, Thomas eHenry   +7 more
doaj   +1 more source

A toxin hunter in the microworld of bacteria: a project on novel inhibitors against bacterial AB5 toxins [PDF]

, 2016
[要旨] 病原性細菌が産生する蛋白性のAB5型トキシンは1個のAサブユニットと5個のBサブユニットから構成される外毒素である。両サブユニットはそれぞれ特徴的な役割を持ち，互いに巧妙に機能分担をして一つのトキシンを形成している。Aサブユニットは主に毒性に直接関与する特異的な酵素活性を有する。一方，Bサブユニットは標的細胞のレセプターに対する結合能を有し，AB5型トキシンを標的細胞に吸着させる。ここでは毒性が全く異なるAB5型トキシンとして，コレラ菌が産生するコレラトキシン（CT ...
Fujun Shen (314092), Jiandong Yang (196004), Rong Hou (149003), Yang Da (89805)   +3 more
core   +3 more sources

Increased Community-Associated Infections Caused by Panton-Valentine Leukocidin–Negative MRSA, Shanghai, 2005–2014

Emerging Infectious Diseases, 2016
During 2005–2014, community-associated methicillin-resistant Staphylococcus aureus infections increased in Shanghai, China. Most infections were caused by sequence type 59 S. aureus that lacked Panton-Valentine leukocidin.
Min Li, Yanan Wang, Yuanjun Zhu, Yingxin Dai, Xufen Hong, Qian Liu, Tianming Li, Juanxiu Qin, Xiaowei Ma, Huiying Lu, Jie Xu, Michael Otto   +11 more
doaj   +1 more source

Serological profiles in nursery piglets colonized with Staphylococcus aureus [PDF]

, 2013
At present, the immune response of pigs in relation to Staphylococcus aureus carriage is poorly understood. This study aimed at investigating the dynamics of the anti-staphylococcal humoral immune response in methicillin-susceptible S.
Barbé, Kurt, Butaye, Patrick, Crombé, Florence, de Vogel, Corné P, Haesebrouck, Freddy, Hermans, Katleen, Van Wamel, Willem J, Vanderhaeghen, Wannes   +7 more
core   +2 more sources

Outbreak of Panton-Valentine Leukocidin–Associated Methicillin-Susceptible Staphylococcus aureus Infection in a Rugby Team, France, 2010–2011

Emerging Infectious Diseases, 2016
Staphylococcus aureus strains that produce Panton-Valentine leukocidin are known to cause community infections. We describe an outbreak of skin abscesses caused by Panton-Valentine leukocidin–producing methicillin-susceptible S.
Elodie Couvé-Deacon, Anne Tristan, Nathalie Pestourie, Christian Faure, Valérie Doffoel-Hantz, Fabien Garnier, Frédéric Laurent, Gerard Lina, Marie-Cecile Ploy   +8 more
doaj   +1 more source

Rapid detection of Staphylococcus aureus Panton-Valentine leukocidin in clinical specimens by enzyme-linked immunosorbent assay and immunochromatographic tests [PDF]

, 2010
10.1128/JCM.02274-09Journal of Clinical Microbiology4841384 ...
Badiou, Cedric, Dumitrescu, Oana, George, Narelle, Forbes, Andrea R. N., Drougka, Eleanna, Chan, Kian Sing, Ramdani-Bouguessa, Nadjia, Meugnier, Helene, Bes, Michele, Vandenesch, Francois, Etienne, Jerome, Hsu, Li Yang, Tazir, Mohamed, Spiliopoulou, Iris, Nimmo, Graeme R., Hulten, Kristina G., Lina, Gerard   +16 more
core   +1 more source

Efficacy of Active Immunization with Attenuated Alpha-Hemolysin and Panton-Valentine Leukocidin in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia.

Journal of Infectious Diseases, 2019
Staphylococcus aureus is a common pathogen causing infections in humans with various degrees of severity, with pneumonia being one of the most severe infections. In as much as staphylococcal pneumonia is a disease driven in large part by alpha-hemolysin (
Vuvi G Tran, Arundhathi Venkatasubramaniam, R. Adhikari, Subramaniam Krishnan, Xing Wang, V. Le, Hoan N. Le, Trang T. Vu, Erika Schneider-Smith, M. Aman, B. Diep   +10 more
semanticscholar   +1 more source

Spontaneous tibiotalar arthrodesis as a complication of acute tibial osteomyelitis due to Panton-Valentine leukocidin-producing Staphylococcus aureus: a case report

Journal of Medical Case Reports, 2012
Introduction Strains of Panton-Valentine leukocidin-producing Staphylococcus aureus producing a new pattern of disease have emerged worldwide. Infection with these bacteria typically presents as a life-threatening infection of soft tissues and bones, and
Ceroni Dimitri, de la Llana Rebecca, Zand Tristan, Lamah Léopold, Dominguez Denis, De Coulon Geraldo, Dubois-Ferrière Victor   +6 more
doaj   +1 more source

Transmission of Staphylococcus aureus from humans to green monkeys in the Gambia as revealed by whole-genome sequencing [PDF]

, 2013
En el marco de la actual crisis económica internacional y las consecuentes políticas de ajuste estructural adoptadas por el gobierno de España desde 2008, la investigación desarrollada centró su atención en los impactos diferenciados sobre un grupo de ...
Weinstock, George, et al,
core   +2 more sources

Community acquired Panton-Valentine Leukocidin (PVL) positive Methicilin Resistant Staphylococcal aureus cerebral abscess in an 11-month old boy: a case study. [PDF]

, 2014
BACKGROUND: Brain abscess are uncommon childhood infection. Brain abscess caused by Panton-Valentine Leukocidin positive Community acquired Methicillin Resistant Staphylococcal aureus have never been reported in the United Kingdom.
Fellows, Greg, Hartley, John, Hudson, Lee, Hulse, Eleanor, Mutale, Wilbroad, Ratnasinghe, Didi, Sahay, Keya M, Thompson, Dominic   +7 more
core   +2 more sources