Disorders of sex development expose transcriptional autonomy of genetic sex and androgen-programmed hormonal sex in human blood leukocytes [PDF]
, 2009 Paul‐Martin Holterhus +10 more
openalex +1 more source
Recent Advances in mRNA Delivery Systems for Cancer Therapy
Advanced Science, EarlyView.This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang +9 more
wiley +1 more source
Haematological evaluation of sodium fluoride toxicity in oryctolagus cunniculus
Toxicology Reports, 2017 Blood is promptly affected by environmental pollutants and toxicants that can cause many metabolic disorders. The high level of fluoride acts as a potential pollutant, insecticide and rodenticide with very high toxicity, associated with the hematological
Maryam Abbas +4 more
doaj
Towards a Mathematical Foundation of Immunology and Amino Acid Chains [PDF]
arXiv, 2012 We attempt to set a mathematical foundation of immunology and amino acid chains. To measure the similarities of these chains, a kernel on strings is defined using only the sequence of the chains and a good amino acid substitution matrix (e.g. BLOSUM62). The kernel is used in learning machines to predict binding affinities of peptides to human leukocyte
arxiv
Engineered Tissue Models to Decode Host–Microbiota Interactions
Advanced Science, EarlyView.Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio +5 more
wiley +1 more source
Microneedle Patch for In Situ Neutrophil Monitoring
Advanced Science, EarlyView.An in situ chromogenic microneedle patch that achieves daily blood neutrophil monitoring without vascular invasion or laboratory apparatus is developed. The detection ability is well demonstrated in a chemotherapy‐induced neutropenic rat model and can be read out using a mobile phone application.
Ziyi Lu +26 more
wiley +1 more source
New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes [PDF]
, 2016 Valentino Bezzerri +8 more
openalex +1 more source
Mycoplasma suis infection in suckling pigs on a Belgian farm [PDF]
, 2008 Mycoplasma suis (formerly known as Eperythrozoon suis) is an epicellular bacterium that affects porcine red blood cells. M. suis infections occur worldwide and are associated with weakness and anemia in suckling and weaned pigs, and reproductive ...
De Busser, Emily Valerie +5 more
core +1 more source
Advanced Science, EarlyView.This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua +19 more
wiley +1 more source
PT614. Altered Serotonin transporter mRNA expression in the peripheral leukocytes of obsessive-compulsive disorder [PDF]
, 2016 Hidehiro Umehara +4 more
openalex +1 more source