Results 251 to 260 of about 245,088 (289)

Disorders of Leukocyte Chemotaxis

Pediatric Clinics of North America, 1977
The rapid accumulation of inflammatory cells at sites of microbial invasion or neoplastic transformation is a central event in immunologically-mediated host defense. The availability of methodology to accurately quantify leukocyte migration in vitro has allowed the disclosure of previously unrecognized clinical disorders, namely leukocyte dysmotility ...
R, Snyderman, M C, Pike
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Disorders of Polymorphonuclear Leukocyte Function

Hospital Practice, 1985
In Part II of the discussion of PMN function, the focus is on ways in which the complex biochemical processes that modulate cell motility and oxygen radical formation can go wrong. Derangements of these functions—hyperactive as well as hypoactive phagocytosis—lead to clinical disorders that predispose the host to infection and inflammatory reactions.
G J, Boxer, J T, Curnutte, L A, Boxer
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Leukocyte function and nonmalignant leukocyte disorders

Current Opinion in Pediatrics, 1993
This review summarizes recent literature regarding the clinical and molecular features of nonmalignant leukocyte disorders in children. Leukocyte adhesion deficiency and chronic granulomatous disease, two inherited disorders of neutrophil function, continue to be the best-characterized disorders with respect to specific molecular defects.
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Leukocyte Function in Chronic Myeloproliferative Disorders

Blood Cells, Molecules, and Diseases, 1998
The myeloproliferative disorders (MPD) are clonal diseases that originate from a transformed stem cell and involve all myeloid lineage. The affected cells have both proliferative and functional impairment. Therefore, we evaluated and compared neutrophil function in 31 patients with polycythemia vera (PV), idiopathic myelofibrosis (MF), chronic myeloid ...
B, Wolach, R, Gavrieli, Y, Manor, M, Lishner   +3 more
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Nonmalignant Disorders of Leukocytes

DeckerMed Medicine, 2011
Leukocytes, also known as white blood cells, are hematologic cells important for a host’s immune defense. They comprise several diverse cell types including lymphocytes, neutrophils, monocytes, macrophages, and eosinophils. Each plays a unique and important role in fighting infection, cancer surveillance, and maintaining immune homeostasis.
Nancy Berliner, Alison M. Schram
openaire   +1 more source

Nonmalignant Leukocyte Disorders

2016
Abnormalities of leukocyte count are routinely encountered in medical practice and rank among the most common reasons for hematologists to be consulted. The question often begins with whether there is a primary hematologic disorder, a clonal malignancy, versus a purely reactive process where the only required therapy would be directed toward the ...
Lawrence Rice, Miho Teruya
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Leukocyte Disorders: Quantitative and Qualitative Disorders of the Neutrophil, Part 2

Pediatrics In Review, 1996
The differential diagnosis for a patient presenting with recurrent infections is formidable, given the complexity of the immune system. The clinical presentation of a patient who has a qualitative neutrophil abnormality may be similar to that of one who has an antibody or complement disorder. In general, evaluation for phagocytic cell disorders (Table)
L A, Boxer, R A, Blackwood
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Clinical Disorders of Leukocyte Functions

1984
After being questioned by a colleague about my current endeavors with a large number of reprints, reference printouts, and writing pads apparent, I informed him that I was writing another review on clinical abnormalities of phagocyte function. Why write another such review, I was asked, as there are a number of these in the current literature (Gallin ...
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Leukocyte Disorders: Quantitative and Qualitative Disorders of the Neutrophil, Part 1

Pediatrics In Review, 1996
Introduction Neutrophils form the first line of defense against most bacterial and fungal pathogens after disruption of the skin and mucous membranes. Once tissue is invaded by microorganisms, a variety of vasoactive and chemotactic mediators are released by the involved tissue.
L A, Boxer, R A, Blackwood
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