Results 261 to 270 of about 245,088 (289)
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Human Leukocyte Antigen Type and Posttransplant Lymphoproliferative Disorder

Transplantation, 2015
Posttransplant lymphoproliferative disorder (PTLD) is an infrequent but serious complication of solid organ transplantation. Early detection and initiation of therapy may improve outcomes. The purpose of this study was to identify human leukocyte antigen (HLA) type as risk and prognostic factors for PTLD.A review was undertaken to identify PTLD cases ...
Mark E, Lustberg   +7 more
openaire   +2 more sources

Disorders of Leukocytes Leading to Recurrent Infection

Pediatric Clinics of North America, 1972
Because they possess the unique property of phagocytosis, certain blood cells appear to be primarily responsible for host defense against pyogenic and fungal infection. The primary phagocyte of the peripheral blood is the polymorphonuclear neutrophil; its functions and their disorders are described in this paper.
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Retinal Blood Velocity in Patients With Leukocyte Disorders

Archives of Ophthalmology, 1988
The blue light entoptic phenomenon was used to measure retinal blood velocity in eight patients with chronic granulocytic leukemia, six patients with leukopenia, and matched control subjects. The retinal leukocyte velocity of the leukemic patients was 0.53 +/- 0.26 (mean +/- SD) mm/s, whereas that of the matched control subjects was 0.46 +/- 0.14 mm/s.
T, Rimmer, E M, Kohner, J M, Goldman
openaire   +2 more sources

Leukocyte mitochondrial DNA copy number in bipolar disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2014
Evidence supports the role for mitochondrial impairment in the pathophysiology of bipolar disorder (BD). BD has been associated with decreased mitochondrial electron transport chain activity and increased oxidative stress. Also, mitochondrial DNA (mtDNA) encodes mitochondrial electron transport chain proteins and has been associated with altered ...
Rafael T, de Sousa   +7 more
openaire   +2 more sources

Leukocyte-Related Disorders: A Review for the Pediatrician

Pediatric Annals, 2020
Leukocytes, or white blood cells, are part of the innate immune system that defends against infectious and foreign agents. In pediatrics, it is important to use age-specific laboratory values when interpreting results. Infections are the most common cause of leukocytosis or leukopenia in children.
openaire   +2 more sources

Deletion of leukocyte mitochondrial DNA in bipolar disorder

Journal of Affective Disorders, 1996
Leukocyte mitochondrial DNA (mtDNA) was examined in 35 patients with bipolar disorder by the nested PCR method to explore whether or not the 4977 base-pair deletion (common deletion) is found. The PCR product corresponding to the common deletion was found in 2 of 35 (5.7%) patients and none of 29 normal controls.
T, Kato, Y, Takahashi
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Physiological Roles of Leukocytes and Disorders

2018
This chapter describes white blood cells of the peripheral blood: neutrophils, eosinophils, basophils, monocytes, and lymphocyte subsets. It describes their basic physiology and important disease states associated with defects of each of these entities. Each of these cells arises from a common bone marrow myeloid or lymphoid progenitor to differentiate
Jahnavi Gollamudi   +2 more
openaire   +1 more source

Leukocyte telomerase activity and antidepressant efficacy in bipolar disorder

European Neuropsychopharmacology, 2014
Telomeres are DNA-protein complexes that cap linear DNA strands, protecting DNA from damage. Recently, shorten telomeres length has been reported in bipolar disorder (BD) and depression. The enzyme telomerase regulates telomeres׳ length, which has been associated with cellular viability; however it is not clear how telomerase may be involved in the ...
Marcio Gerhardt, Soeiro-de-Souza   +9 more
openaire   +2 more sources

WHIM syndrome: a genetic disorder of leukocyte trafficking

Current Opinion in Allergy and Clinical Immunology, 2003
WHIM syndrome (the association of warts, hypogammaglobulinemia, recurrent bacterial infections, and 'myelokathexis') is a rare congenital form of neutropenia associated with an unusual immune disorder involving hypogammaglonulinemia and abnormal susceptibility to warts.
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[Glycosaminoglycans in leukocytes in myeloproliferative disorders].

Voprosy meditsinskoi khimii, 1984
Content and composition of glycosaminoglycans (GAG) was studied in leukocytes of 30 healthy persons and of patients with different types of myeloproliferative disorders: 32 patients with chronic myeloid leukemia (CML), 10 patients with polycythemia vera (PV), 5 patients with idiopathic myeloid fibrosis (IMF) and 10 patients with acute myelo blast ...
M F, Kharchenko   +4 more
openaire   +1 more source

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