Alcohol consumption and leukocyte telomere length. [PDF]
, 2019 The relationship between alcohol consumption and mortality generally exhibits a U-shaped curve. The longevity observed with moderate alcohol consumption may be explained by other confounding factors, and, if such a relationship is present, the mechanism ...
Dixit, Shalini +9 more
core +2 more sources
Case Reports in Hematology, 2013 Myeloproliferative disorders are variable disorders, based on the genetic abnormality present and the cell line progenitors that are affected. In this case, we discuss a novel gene translocation in the subset of PDGFRB mutations, first seen with ...
Joel D. Provenzano, J. Phillip Kuebler
doaj +1 more source
Optimization and pharmacological validation of a leukocyte migration assay in zebrafish larvae for the rapid in vivo bioactivity analysis of anti-inflammatory secondary metabolites. [PDF]
PLoS ONE, 2013 Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug discovery. In this study, we explore the suitability of zebrafish larvae to rapidly evaluate the anti-inflammatory activity of natural products (NPs) and ...
María Lorena Cordero-Maldonado +6 more
doaj +1 more source
Frontiers in Veterinary Science, 2023 IntroductionPituitary pars intermedia dysfunction (PPID) and dental disorders are of major concern in horses older than 15 years. Although PPID in geriatric horses and dental disorders in all age groups are well described, a connection between this ...
Anne Maria Zapf +4 more
doaj +1 more source
Cancer-driven dynamics of immune cells in a microfluidic environment [PDF]
Nature Scientific Reports 4, 6639 (2014), 2014 Scope of the present work is to frame into a rigorous, quantitative scaffold - stemmed from stochastic process theory - two sets of experiments designed to infer the spontaneous organization of leukocytes against cancer cells, namely mice splenocytes vs.
arxiv +1 more source
Reduction of leukocyte microvascular adherence and preservation of blood-brain barrier function by superoxide-lowering therapies in a piglet model of neonatal asphyxia [PDF]
, 2019 Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the hypothesis that superoxide radical (
Aarti R. Shah +9 more
core +2 more sources
Large-scale associations between the leukocyte transcriptome and BOLD responses to speech differ in autism early language outcome subtypes. [PDF]
, 2018 Heterogeneity in early language development in autism spectrum disorder (ASD) is clinically important and may reflect neurobiologically distinct subtypes.
A Battle +82 more
core +1 more source
Inverse modeling of time-delayed interactions via the dynamic-entropy formalism [PDF]
arXiv, 2023 Although instantaneous interactions are unphysical, a large variety of maximum entropy statistical inference methods match the model-inferred and the empirically-measured equal-time correlation functions. Focusing on collective motion of active units, this constraint is reasonable when the interaction timescale is much faster than that of the ...
arxiv
Predictive significance of the six-minute walk distance for long-term survival in chronic hypercapnic respiratory failure [PDF]
, 2008 Background: The 6-min walk distance ( 6-MWD) is a global marker of functional capacity and prognosis in chronic obstructive pulmonary disease ( COPD), but less explored in other chronic respiratory diseases.
Aida A +39 more
core +1 more source
Dissecting the limited genetic overlap of Parkinson's and Alzheimer's disease
Annals of Clinical and Translational Neurology, 2022 Parkinson's disease and Alzheimer's disease show overlapping features both clinically and neuropathologically and elucidating shared mechanisms could have important implications for therapeutic strategies.
Maren Stolp Andersen +5 more
doaj +1 more source