Results 61 to 70 of about 237,141 (361)
Indian Journal of Transplantation, 2018 Stem cell transplant (SCT) is the “standard of care” for several malignant disorders such as leukemia as well as nonmalignant disorders such as thalassemia and aplastic anemia.
Vikash Chandra Mishra +3 more
doaj +1 more source
L-selectin mediated leukocyte tethering in shear flow is controlled by multiple contacts and cytoskeletal anchorage facilitating fast rebinding events [PDF]
PNAS 101: 6940-6945 (2004), 2005 L-selectin mediated tethers result in leukocyte rolling only above a threshold in shear. Here we present biophysical modeling based on recently published data from flow chamber experiments (Dwir et al., J. Cell Biol. 163: 649-659, 2003) which supports the interpretation that L-selectin mediated tethers below the shear threshold correspond to single L ...
arxiv +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Leukocyte Classification using Multimodal Architecture Enhanced by Knowledge Distillation [PDF]
arXiv, 2022 Recently, a lot of automated white blood cells (WBC) or leukocyte classification techniques have been developed. However, all of these methods only utilize a single modality microscopic image i.e. either blood smear or fluorescence based, thus missing the potential of a better learning from multimodal images.
arxiv
Exogenous application of platelet-leukocyte gel during open subacromial decompression contributes to improved patient outcome [PDF]
, 2007 Background: Platelet-leukocyte gel (PLG) is being used during various surgical procedures in an attempt to enhance the healing process. We studied the effects of PLG on postoperative recovery of patients undergoing open subacromial decompression (OSD ...
Devilee, R. +7 more
core +2 more sources
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
ErbB3 mRNA leukocyte levels as a biomarker for major depressive disorder [PDF]
BMC Psychiatry, 2012 Abstract Background In recent years, the identification of peripheral biomarkers that are associated with psychiatric diseases, such as Major Depressive Disorder (MDD), has become relevant because these biomarkers may improve the efficiency of the differential diagnosis process and indicate targets for new ...
Milanesi E +11 more
openaire +5 more sources
Intercellular Adhesion Molecule 1: More than a Leukocyte Adhesion Molecule
Biology, 2023 Intercellular adhesion molecule 1 (ICAM-1) is a transmembrane protein in the immunoglobulin superfamily expressed on the surface of multiple cell populations and upregulated by inflammatory stimuli.
Cameron D. Haydinger +3 more
doaj +1 more source
Towards Interpretable Classification of Leukocytes based on Deep Learning [PDF]
arXiv, 2023 Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify cells with high accuracy where the human observer has little chance to discriminate cells.
arxiv
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]
, 1993 Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR +3 more
core +1 more source