Molecular and Cellular Differences in Cardiac Repair of Male and Female Mice
Background Leukocyte‐directed biosynthesis of specialized proresolving mediators (SPMs) orchestrates physiological inflammation after myocardial infarction.
Amanda B. Pullen+3 more
doaj +1 more source
CD11c immunopositive cells in the human fetal vermiform appendix [PDF]
Introduction/Aim. A vermiform appendixis an abdominal organ which contains the elements of gut-associated lymphoid tissue and carries out important immunological functions as a reservoir of intestinal microbial flora.
Radenković Goran+5 more
doaj +1 more source
The pulmonary circulation harbors a large intravascular reservoir of leukocytes refered to as the Marginated Pool. This marginated pool is balanced by propeling and retaining forces acting on leukocytes during their passage through the pulmonary ...
Goetz, Alwin Eduard+1 more
core +1 more source
Leukocyte adhesion - a fundamental process in leukocyte physiology [PDF]
Leukocyte adhesion is of pivotal functional importance. The adhesion involves several different adhesion molecules, the most important of which are the leukocyte beta 2-integrins (CD11/CD18), the intercellular adhesion molecules, and the selectins.
Gahmberg, C. G.+7 more
openaire +7 more sources
Leukocyte sequestration in pulmonary microvessels and lung injury following systemic complement activation in rabbits [PDF]
Inflammatory reactions are associated with sequestration of leukocytes in the lung. Complement activation leads to accumulation of leukocytes in alveolar septa and alveoli, to lung edema and hemorrhage.
Goetz, Alwin Eduard+5 more
core +1 more source
PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells [PDF]
Interactions between leukocytes and vascular endothelial cells are mediated by a complex set of membrane adhesion molecules which transduce bi-directional signals in both cell types.
Adamson+53 more
core +2 more sources
Pyroptotic Patterns in Blood Leukocytes Predict Disease Severity and Outcome in COVID-19 Patients
The global coronavirus disease 2019 (COVID-19) pandemic has lasted for over 2 years now and has already caused millions of deaths. In COVID-19, leukocyte pyroptosis has been previously associated with both beneficial and detrimental effects, so its role ...
Yingkui Tang+5 more
doaj +1 more source
Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells [PDF]
The T cell immunoglobulin and mucin domain 3 (Tim-3) is a plasma membrane-associated receptor which is involved in a variety of biological responses in human immune cells.
Bardelli, Marco+4 more
core +2 more sources
Transfusion of Leukocytes and Products of Disintegrated Leukocytes.
Summary and Conclusions1. Leukocytes were obtained in large numbers by introduction of large amounts of physiologic salt solution into the peritoneal cavity of rabbits.2. Intravenous administration of these cells to the same or different animals was followed by very rapidly developing and severe leukopenia.
Austin S. Weisberger+2 more
openaire +3 more sources
Leukocyte margination in alveolar capillaries: Interrelationship with functional capillary geometry and microhemodynamics [PDF]
The pulmonary capillary microvasculature harbors a large pool of intravascularly marginated leukocytes. In this study, we investigated the interrelationship of leukocyte margination with characteristics of functional capillary geometry and ...
Goetz, Alwin Eduard+2 more
core +1 more source