Results 101 to 110 of about 241,803 (259)

Bovine colostrum and immune function after exercise [PDF]

, 2012
Strenuous and/or prolonged exercise causes transient perturbations in immune function. It is well accepted that this is one mechanism contributing to the higher occurrence of infection (e.g.
Glen Davison, Davison, Glen
core   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Modification of platelet aggregation by leukocytes in acute ischemic stroke.

, 1994
Platelet aggregation plays an important role in the pathogenesis of thromboembolic cerebrovascular disease. Leukocytes can efficiently stimulate as well as inhibit platelet aggregability.
R Sigmund, W Hacke, A J Grau
core   +1 more source

Mononuclear Leukocyte Cyclic Adenosine Monophosphate Responses in Psoriasis Are Normal [PDF]

, 1984
It has been proposed that immune dysfunction in psoriasis is a consequence of aberrent cyclic nucleotide metabolism. We have examined cyclic AMP responses to isoprenaline, histamine, and prostaglandin E2 in peripheral blood mononuclear leukocytes from ...
Macdonald, D.M., Hanson, Jennifer M, Morley, J., Archer, C B   +3 more
core   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

The Cytotoxic Effects of Sio2 Nanoparticles on Human Blood Mononuclear Cells

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2012
Introduction: Regarding the increasing use of silicon dioxide nanoparticles in medical biotechnology and probable side effects and diseases resulting from its usage, this study was performed to assess the toxic effects of different concentrations of SiO2
A Jebali, H Hekmatimoghaddam, s Barzegar, H Fallahzadeh, A Barkhordari   +4 more
doaj  

Low-Density-Lipoprotein Receptor and 3-Hydroxy-3-Methylglutaryl Coenzyme-A Reductase Gene-Expression in Human Mononuclear Leukocytes Is Regulated Coordinately and Parallels Gene-Expression in Human Liver

, 1994
The liver plays a key regulatory role in cholesterol metabolism. Two proteins are central in this role; the LDL receptor and 3-hydroxy-3-methylglutaryl CoA reductase (HMG CoA reductase), the rate-limiting enzyme in cholesterol biosynthesis.
Powell, EE, P A Kroon, E E Powell, Kroon, PA   +3 more
core   +1 more source

Antioxidant effects of anthocyanins-rich extract from black sticky rice on human erythrocytes and mononuclear leukocytes [PDF]

, 2015
The present study was aimed at determining the optimum dose of anthocyanins-rich extract (ARE) from Thai pigmented rice for its antioxidant effects. Three different methods of antioxidant analysis [Oxygen Radical Absorbance Capacity (ORAC) assay, Folin ...
Tencomnao, Tewin, Sangkitikomol, Warin, Rocejanasaroj, Atittaya   +2 more
core   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Molecular mechanisms of regulatory action of heat shock protein 27 kDa in the apoptosis of tumor cells

Бюллетень сибирской медицины, 2011
Score mRNA expression and the level of Hsp27 (Heat shock protein 27) and phospho-Hsp27 in tumor cell line Jurkat and THP-1, as well as in mononuclear leukocytes obtained from healthy donors was investigated.
Ye. V. Kaigorodova
doaj   +1 more source