Results 31 to 40 of about 241,803 (259)

Chemokine-Decorated Nanoparticles Target Specific Subpopulations of Primary Blood Mononuclear Leukocytes

Nanomaterials, 2022
Specific cell targeting to deliver nanoparticles can be achieved by tailored modifications of the material surface with chemical moieties. The selection of the cell targets can be optimized by covering the nanoparticle with molecules, the receptor ...
Anissa Pisani, Roberto Donno, Giulio Valenti, Pier Paolo Pompa, Nicola Tirelli, Giuseppe Bardi   +5 more
doaj   +1 more source

SUBPOPULATIONS AND METABOLIC ACTIVITY OF BLOOD MONONUCLEAR CELLS IN METABOLIC SYNDROME

Медицинская иммунология, 2014
Aim of study: to examine the features of expression of CD-markers of blood mononuclear leukocytes and their functional activity in the metabolic syndrome.
I. D. Bespalovа, N. V. Ryazantseva, V. V. Kalyuzhin, B. Yu. Murashev, I. A. Osikhov, Y. A. Medyantsev, D. S. Afanas’eva   +6 more
doaj   +1 more source

Molecular characterization and functional implications on mouse peripheral blood mononuclear cells of annexin proteins from Echinococcus granulosus sensu lato

Parasites & Vectors, 2023
Background Cystic echinococcosis (CE) is a life-threatening zoonotic disease caused by the larval stage of Echinococcus granulosus sensu lato, which employs various strategies to evade the host immune system for survival.
Xue He, Guoqing Shao, Xiaodi Du, Ruiqi Hua, Hongyu Song, Yanxin Chen, Xiaowei Zhu, Guangyou Yang   +7 more
doaj   +1 more source

Oxidative Stress in Patients with Advanced CKD and Renal Replacement Therapy: The Key Role of Peripheral Blood Leukocytes

Antioxidants, 2021
Oxidative stress plays a key role in the pathophysiology of chronic kidney disease (CKD). Most studies have investigated peripheral redox state focus on plasma, but not in different immune cells.
Carmen Vida, Carlos Oliva, Claudia Yuste, Noemí Ceprián, Paula Jara Caro, Gemma Valera, Ignacio González de Pablos, Enrique Morales, Julia Carracedo   +8 more
doaj   +1 more source

Influence of polyamines of bacterial origin on the production of key cytokines in the culture of human mononuclear leukocytes

Медицинская иммунология, 2022
To date, participation of biogenic polyamines has been studied in details, with respect to regulation of microbial gene expression, interrelations between bacteria, development of their persistence state.
A. P. Godovalov, T. I. Karpunina
doaj   +1 more source

Isolation of Infiltrating Leukocytes from the Spinal Cord of Mice

Bio-Protocol, 2013
The infiltration of leukocytes into the central nervous system (CNS) is a common feature of many neuroinflammatory diseases such as multiple sclerosis, and also occurs during certain microbial infections such as by West Nile Virus.
Julia Martinez Gomez, Stephan Gasser, Herbert Schwarz   +2 more
doaj   +1 more source

LEPTIN AS AN INDUCER OF INFLAMMATION AND OXIDATIVE STRESS BY METABOLIC SYNDROME

Бюллетень сибирской медицины, 2014
Object of research: to explore the relationship of leptin level in blood serum with markers of systemic inflammation and spontaneous production of cytokines and reactive oxygen species by blood mononuclear leukocytes at metabolic syndrome.Material and ...
I. D. Bespalovа
doaj   +1 more source

Immunological response of human leucocytes after exposure to lipopolysaccharides from Porphyromonas gingivalis

Clinical and Experimental Dental Research, 2021
Porphyromonas gingivalis (P. gingivalis) is a gram‐negative bacterium and an important etiologic agent of periodontitis. P. gingivalis releases outer membrane vesicles containing lipopolysaccharides (LPS), which can penetrate periodontal tissues. Once in
Sara Alizadehgharib, Anna‐Karin Östberg, Agnes Dahlstrand Rudin, Ulf Dahlgren, Karin Christenson   +4 more
doaj   +1 more source

Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol Δ7-reductase in liver and mononuclear leukocytes

Journal of Lipid Research, 1998
Sitosterolemia is a recessively inherited disorder characterized by abnormally increased plasma and tissue plant sterol concentrations. Patients have markedly reduced whole body cholesterol biosynthesis associated with suppressed hepatic, ileal, and ...
Akira Honda, Gerald Salen, Lien B. Nguyen, G. Stephen Tint, Ashok K. Batta, Sarah Shefer   +5 more
doaj   +1 more source

An Altered Metabolism in Leukocytes Showing in vitro igG Memory From SARS-CoV-2-Infected Patients

Frontiers in Molecular Biosciences, 2022
Coronavirus disease 2019 (COVID 19) is a systemic infection that exerts a significant impact on cell metabolism. In this study we performed metabolomic profiling of 41 in vitro cultures of peripheral blood mononuclear cells (PBMC), 17 of which displayed ...
G. Fanelli, F. Gevi, G. Zarletti, M. Tiberi, V. De Molfetta, G. Scapigliati, A. M. Timperio   +6 more
doaj   +1 more source