Results 81 to 90 of about 80,122 (309)

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Leukocyte and Platelet Characteristics of the Giant Panda (Ailuropoda melanoleuca): Morphological, Cytochemical, and Ultrastructural Features

Frontiers in Veterinary Science, 2020
The giant panda (Ailuropoda melanoleuca) is a vulnerable species and a charismatic member of zoological collections worldwide. Despite its importance as a representative species for global wildlife conservation efforts, no studies to date have described ...
Spencer P. Kehoe, Nicole I. Stacy, Salvatore Frasca, Tracy Stokol, Chengdong Wang, Kathryn Strayer Leach, Li Luo, Sam Rivera   +7 more
doaj   +1 more source

Theileria annulata and T. parva infect and transform different bovine mononuclear cells

, 1989
Bovine peripheral blood mononuclear cells (PBMC) were labelled with monoclonal antibodies recognizing bovine MHC class II, sIgM, monocyte, T-helper and T-cytotoxic cell phenotypes.
Brown, C G, Innes, E A, Spooner, R L, Glass, E J   +3 more
core  

Modification of platelet aggregation by leukocytes in acute ischemic stroke.

, 1994
Platelet aggregation plays an important role in the pathogenesis of thromboembolic cerebrovascular disease. Leukocytes can efficiently stimulate as well as inhibit platelet aggregability.
R Sigmund, W Hacke, A J Grau
core   +1 more source

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, EarlyView.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis

Бюллетень сибирской медицины, 2012
The results of research the cytokine-secretion activity of mononuclear leukocytes, apoptosis and proliferation of lymphocytes for patients with infiltrative pulmonary tuberculosis has been presented in this article.
T. Ye. Kononova, O. I. Urazova, V. V. Novitsky, Ye. G. Churina, M. V. Ignatov   +4 more
doaj   +1 more source

Mineralocorticoid effector mechanism of liquorice derivatives in human mononuclear leukocytes.

, 1989
The mineralocorticoid effector mechanism of glycyrrhetinic acid and of its ester derivative carbenoxolone was evaluated in human mononuclear leukocytes by radioreceptorassay and measurement of intracellular sodium and potassium after incubation of the ...
WEHLING M, WEBER PC, ARMANINI, DECIO
core  

Low-Density-Lipoprotein Receptor and 3-Hydroxy-3-Methylglutaryl Coenzyme-A Reductase Gene-Expression in Human Mononuclear Leukocytes Is Regulated Coordinately and Parallels Gene-Expression in Human Liver

, 1994
The liver plays a key regulatory role in cholesterol metabolism. Two proteins are central in this role; the LDL receptor and 3-hydroxy-3-methylglutaryl CoA reductase (HMG CoA reductase), the rate-limiting enzyme in cholesterol biosynthesis.
Powell, EE, P A Kroon, E E Powell, Kroon, PA   +3 more
core   +1 more source

Hepatic morphology and serum biochemical profile according to dry and rainy seasons in Pygocentrus nattereri (Characiformes: Serrasalmidae)

The Anatomical Record, EarlyView.
Abstract This study investigated the physiological and morphological adaptations of the liver of the carnivorous fish Pygocentrus nattereri (piranha) in response to seasonal variations (dry and rainy seasons) in the Brazilian Pantanal. The objective was to describe how the liver, a central organ in metabolic regulation, responds to environmental ...
Maria Eduarda Corona Garcia, Sandriely F. Marcondes, Mayara S. Siqueira, Taynara R. F. Leão, Robson A. Rodrigues, Karine N. N. Farias, André L. N. Silva, Karin Virgínia Kuibida, Lilian Franco‐Belussi, Carlos E. Fernandes   +9 more
wiley   +1 more source

ROLE OF ENDOCANNABINOID RECEPTORS IN IMMUNE RESPONSE REGULATION

Медицинская иммунология, 2014
. Expression of endocannabinoid receptors (СВ1, СВ2) in immunocompetent cells was studied under the conditions of in vivo stimulation of immune system. Intracorporeal blood irradiation and enrichment of peripheral blood by ozone/oxygen mixture were used ...
E. G. Lobanova
doaj   +1 more source