Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros +2 more
wiley +1 more source
Short-interval longitudinal analysis of immune cell dynamics in heavy draft foals after colostrum intake. [PDF]
Yoshida S, Takeyama A, Maeda Y, Nambo Y.
europepmc +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
Analysis of Cytological Markers of Cellular Senescence in High-Risk Cardiovascular Patients After COVID-19. [PDF]
Kyryk V +4 more
europepmc +1 more source
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf +5 more
wiley +1 more source
Diagnostic Yield of Routine Pericardial Fluid Cultures and Clinical Predictors of Bacterial Pericarditis. [PDF]
Orlev A +4 more
europepmc +1 more source
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche +11 more
wiley +1 more source
Beyond typical pathogens: pleural empyema caused by <i>Aggregatibacter aphrophilus</i>. [PDF]
Dias B +4 more
europepmc +1 more source
The immunogenicity of donor kidneys on NMP can be studied using monocyte‐derived dendritic cells. Incubation with perfusate showed an anti‐inflammatory dendritic cell phenotype and function that suggests the release of an anti‐inflammatory factor or factors during NMP. ABSTRACT Background The immunomodulatory activity of normothermic machine perfusion (
Laura W. D. Knijff +8 more
wiley +1 more source
Identification, characterization, and expansion of innate lymphoid cells derived from canine peripheral blood mononuclear cells. [PDF]
Mehrani Y +8 more
europepmc +1 more source

