Engineered Probiotic‐Powered Micro‐Rod Robot Bomb for Thrombus‐Penetrating Explosion
For thrombotic diseases with narrow therapeutic windows and persistent vascular damage; existing thrombolytic drugs are difficult to achieve precise; timely; and sustained thrombolytic effects. Here an engineered probiotic driven micro‐rod robot for targeted and penetrative treatment for thrombus is developed.
Riyue Liu+8 more
wiley +1 more source
There is no transfer of mitochondria from donor hematopoietic cells to recipient mesenchymal stromal cells after allogeneic hematopoietic stem cells transplantation in humans. [PDF]
Sats N+11 more
europepmc +1 more source
Guidance of ganciclovir therapy with pp65 antigenemia in cytomegalovirus-free recipients of livers from seropositive donors [PDF]
Fung, J+7 more
core
To solve the challenge of PROTACs in clinical potential due to poor water solubility and membrane permeability, a nanodelivery system based on lipid nanodisks loaded with MZ1 prodrug (LND‐MZ1) to remodel the physicochemical and pharmacokinetic properties of PROTAC MZ1 is elaborately proposed.
Meichen Pan+6 more
wiley +1 more source
The In Vitro Effects of Choline on Non-Esterified Fatty Acid-Treated Bovine Peripheral Blood Leukocytes. [PDF]
Li CY+4 more
europepmc +1 more source
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan+12 more
wiley +1 more source
Advanced leukocyte classification using attention mechanisms and dual channel U-Net architecture. [PDF]
Kalnoor G, Kadrolli V.
europepmc +1 more source
Granulocyte elastase as a sensitive diagnostic parameter of silent male genital tract inflammation [PDF]
Jochum, Marianne+2 more
core
Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai+5 more
wiley +1 more source