Results 21 to 30 of about 594,733 (360)

Extracellular DNA—A Danger Signal Triggering Immunothrombosis

Frontiers in Immunology, 2020
Clotting and inflammation are effective danger response patterns positively selected by evolution to limit fatal bleeding and pathogen invasion upon traumatic injuries.
Chongxu Shi, Luying Yang, Attila Braun, Hans-Joachim Anders   +3 more
doaj   +1 more source

The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model

Platelets, 2023
Cryopreservation significantly alters the phenotype of platelets; generating distinct subpopulations, which may influence the formation of platelet leukocyte aggregates (PLA). PLAs are immunomodulatory and have been associated with transfusion-associated
Ben Winskel-Wood, Matthew P. Padula, Denese C. Marks, Lacey Johnson   +3 more
doaj   +1 more source

Leukocyte Trafficking and Hemostasis in the Mouse Fetus in vivo: A Practical Guide

Frontiers in Cell and Developmental Biology, 2021
In vivo observations of blood cells and organ compartments within the fetal mammalian organism are difficult to obtain. This practical guide describes a mouse model for in vivo observation of the fetal yolk-sac and corporal microvasculature throughout ...
Andreas Margraf, Andreas Margraf, Markus Sperandio   +2 more
doaj   +1 more source

TGF-b2 induction regulates invasiveness of theileria-transformed leukocytes and disease susceptibility [PDF]

, 2010
Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible animals usually die within weeks of infection, but indigenous infected cattle show markedly reduced
A Moustakas, A Tsapara, Brian R. Shiels, D Haller, DA Dobbelaere, Dirk Werling, DJ Brown, DK Singh, E Schreiber, EJ Glass, EJ Glass, Elizabeth J. Glass, F Biname, F Plattner, G Steger, Gordon Langsley, GT Charras, J Guergnon, J Ham, J Massague, J Massague, Jonathan B. Weitzman, JS Kim, K Jensen, K McGuire, Kirsty Jensen, M Baumgartner, M Cordenonsi, Marie Chaussepied, Martin Baumgartner, MF Moreau, MW Pfaffl, Natacha Janski, PJ Hanley, R Adamson, R Breitling, R Lizundia, R Lizundia, RA Irizarry, Regina Lizundia, RP Somerville, S Itoh, S Narumiya, SS Huang, TL Criswell, TV Do, V Sanz-Moreno, V Sanz-Moreno, Volker Theo Heussler, William Weir, YE Zhang, YM Fleming   +51 more
core   +6 more sources

Maternal and infant infections stimulate a rapid leukocyte response in breastmilk [PDF]

, 2013
Breastmilk protects infants against infections; however, specific responses of breastmilk immune factors to different infections of either the mother or the infant are not well understood. Here, we examined the baseline range of breastmilk leukocytes and
Filgueira, L, Hartmann, P, Hassiotou, F, Hepworth, A, Lai, C, Metzger, P, Trengove, N   +6 more
core   +3 more sources

The leukocyte podosome

European Journal of Cell Biology, 2006
Myeloid leukocytes are the first line of host defence. When they sense perturbations in tissue homeostasis such as infection, inflammation and ischemia, they respond by trafficking. Whilst neutrophils and macrophages migrate to sites of infection, dendritic cells (DC) migrate from tissue-resident sites back into lymph nodes where they activate T and B ...
Calle, Y, Burns, S, Thrasher, A J, Jones, G E   +3 more
openaire   +4 more sources

Physiological fibrin hydrogel modulates immune cells and molecules and accelerates mouse skin wound healing

Frontiers in Immunology, 2023
IntroductionWound healing is a complex process to restore homeostasis after injury and insufficient skin wound healing is a considerable problem in medicine.
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Mostafa EzEldeen, Estefania Ugarte-Berzal, Erik Martens, Bert Malengier-Devlies, Jennifer Vandooren, Jan Jeroen Vranckx, Jan Jeroen Vranckx, Patrick Matthys, Ghislain Opdenakker   +10 more
doaj   +1 more source

Severity of experimental escherichia-coli mastitis in ketonemic and nonketonemic dairy-cows. [PDF]

, 1993
The severity of experimental Escherichia coli mastitis in relation to in vitro chemotaxis of polymorphonuclear leukocytes was investigated in cows during negative energy balance. The negative energy balance was induced by feed restriction.
Brand, A, Burvenich, Christian, Grommers, FJ, Heeringa, R, Kremer, WDJ, Noordhuizen-Stassen, EN, Schukken, YH   +6 more
core   +1 more source

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]

, 2020
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea, De Baetselier, Patrick, De Trez, Carl, Korf, Hannelie, Magez, Stefan, Stijlemans, Benoit, Van Ginderachter, Jo A   +6 more
core   +1 more source

Apoptosis- and survival-related gene mRNA profile in peripheral blood leukocytes in children with acute EBV infectious mononucleosis

Инфекция и иммунитет, 2020
Acute EBV-associated mononucleosis develops mainly in children and in patients with functionally impaired immune system. Consequently, it may result in developing secondary immunodeficiency, neoplasms as well as diverse alterations in cell-mediated ...
N. A. Sakharnov, O. V. Utkin, E. N. Filatova, D. I. Knyazev, N. B. Presnyakova   +4 more
doaj   +1 more source