Changes in cellular metabolism, development of oxidative-nitrative stress and intensification of glycation and lipid peroxidation (LPO), are significant processes that occur during diabetes mellitus (DM)-associated chronic hyperglycemia.
Bila Ivanna+3 more
doaj +1 more source
Innate immune basis for rift valley fever susceptibility in mouse models [PDF]
Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre+7 more
core +2 more sources
Kidney surveillance in the spotlight: contrast-induced acute kidney injury illuminated [PDF]
Acute kidney injury comprises a heterogeneous group of conditions characterized by a sudden decrease in renal function over hours to days. Contrast-induced acute kidney injury (CI-AKI) is caused by radiographic contrast agents used in diagnostic imaging.
Atkinson, Simon J.
core +1 more source
Quick Leukocyte Nucleus Segmentation in Leukocyte Counting [PDF]
The leukocyte nucleus quick segmentation is one of the key techniques in leukocyte real-time online scanning of human blood smear. We propose a quick leukocyte nucleus segmentation method based on the component difference in RGB color space. By analyzing the captured microscopic images of the peripheral blood smears from the autoscanning microscope, it
Yapin Wang, Yiping Cao
openaire +3 more sources
Effect of boxing competition on S100-B, CRP and leukocytes levels in elite boxers [PDF]
Effect of boxing competition on S100-B, CRP and leukocytes levels in elite boxersPurpose: Combat sports are associated event with a possible head injury and brain damage and the incidenceof concussion and head injuries in boxing than any other sport but,
علی محمدی منش+3 more
doaj +1 more source
Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders. [PDF]
The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a
Agrawal, Rahul+5 more
core +2 more sources
OBJETIVO: Avaliar a importância da interação entre a integrina Mac-1 dos leucócitos (a Mb 2) e a glicoproteína (GP) Iba das plaquetas para o recrutamento de leucócitos após a lesão vascular e o efeito da neutralização da interação Mac-1-GPIba sobre a ...
Alexandre C. Zago+8 more
doaj +1 more source
Effects of NO synthase inhibitors on the synovial microcirculation in the mouse knee joint [PDF]
Production of nitric oxide by the inducible NO synthase (iNOS) is known to be enhanced in chronic joint inflammation and osteoarthritis as well as aseptic loosening of joint prostheses.
Krombach, F.+3 more
core +1 more source
The peroxidation of leukocytes index ratio reveals the prooxidant effect of green tea extract [PDF]
Despite tea increased plasma nonenzymatic antioxidant capacity, the European Food Safety Administration (EFSA) denied claims related to tea and its protection from oxidative damage.
Longhitano, Yaroslava+6 more
core +8 more sources
Andrographolide Inhibits Expression of NLPR3 Inflammasome in Canine Mononuclear Leukocytes
Inflammasomes are multiprotein complexes that trigger processes through caspase-1 activation, leading to the maturation of proinflammatory cytokines, such as IL-1β and IL-18.
Alejandro Albornoz+8 more
doaj +1 more source