Results 41 to 50 of about 375,888 (308)

Are changes in HSPA1A, HSPB1 and LDHb genes expression during physical performance ”till exhaustion” independent of their exercise possibility?

Baltic Journal of Health and Physical Activity, 2014
Background: The aim of the study was to designate changes in the expression of HSPA1A, HSPB1 and LDHb in elite rowers after completing a test “till exhaustion” on a rowing ergometer.
Jastrzebski Zbigniew, Zychowska Malgorzata   +1 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Exercise‐induced amplification of mitogen‐stimulated oxidative burst in whole blood is strongly influenced by neutrophil counts during and following exercise

Physiological Reports, 2021
This study characterized the effect of moderate‐ or vigorous‐intensity exercise on leukocyte counts, using fingertip sampling, and mitogen‐stimulated oxidative burst, measured in whole blood with a point‐of‐care test. In a randomized crossover design, 13
A. Lester, G. L. Vickers, L. Macro, A. Gudgeon, A. Bonham‐Carter, J. P. Campbell, J. E. Turner   +6 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Estudo do método da extração da camada leucoplaquetária na produção de hemocomponentes: avaliação laboratorial A study of the Buffy-coat extraction method for blood component processing: laboratorial analysis

Revista Brasileira de Hematologia e Hemoterapia, 2004
Dentre os métodos para a obtenção de hemocomponentes destaca-se o método do plasma rico em plaquetas (PRP) e o método da extração da camada leucoplaquetária (ECLP).
Mario I. Serinolli, Márcia C. Z. Novaretti, Pedro E. Dorlhiac-Lacer, Dalton A. F. Chamone   +3 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Enhancing Biomarker Detection and Imaging Performance of Smartphone Fluorescence Microscopy Devices

Biosensors
Fluorescence microscopy enabled by smartphone-coupled 3D instruments has shown utility in different biomedical applications ranging from diagnostics to biomanufacturing.
Muhammad Ahsan Sami, Muhammad Nabeel Tahir, Umer Hassan   +2 more
doaj   +1 more source

UJI TOKSISITAS SUBKRONIS EKSTRAK CURCUMA BEBAS MINYAK ATSIRI (ECBA) DITINJAU DARI PARAMETER PROFIL LEUKOSIT PADA TIKUS PUTIH GALUR WISTAR

Pharmaciana, 2014
The effect of Volatil Oil of Curcuma Extraxt or Curcumin extract with centration of essential oil in reducing the levels of cholesterol in the blood has been ECBA as antihyperlipidemic agent is given for a long - term therapeutic purpose.
Verda Farida, Zullies Ikawati, Suwidjiyo Pramono   +2 more
doaj   +1 more source

Effect of leukoreduction on inflammation in critically ill dogs receiving red blood cell transfusions: A randomized blinded controlled clinical trial

Journal of Veterinary Internal Medicine, 2022
Background Prestorage leukoreduction of red blood cell (RBC) bags prevents accumulation of pro‐inflammatory mediators and experimentally attenuates post‐transfusion inflammation in healthy dogs.
Melissa A. Claus, Denise Poh, Lisa Smart, Sarah L. Purcell, Corrin J. Boyd, Claire R. Sharp   +5 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source