Surgical outcomes of dermabrasion followed by split-thickness skin grafting for post-burn leukoderma: a two-center observational study [PDF]
Background Post-burn leukoderma is a challenging late sequela of deep dermal injury, characterized by persistent hypopigmentation and impaired scar quality.
Abdulkadir Calavul
doaj +2 more sources
In Vitro Methods for Predicting Chemical Leukoderma Caused by Quasi-Drug Cosmetics
Skin care cosmetics frequently contain whitening or lightening agents. The present study aimed to establish in vitro methods for predicting chemical leukoderma caused by whitening agents in cosmetics. The risks of chemical leukoderma were predicted based
Kazuhisa Maeda, Maeda Kazuhisa
exaly +3 more sources
A Cell-Based Evaluation of the Tyrosinase-Mediated Metabolic Activation of Leukoderma-Inducing Phenols, II: The Depletion of Nrf2 Augments the Cytotoxic Effect Evoked by Tyrosinase in Melanogenic Cells [PDF]
Chemical leukoderma is a disorder induced by chemicals such as rhododendrol and monobenzone. These compounds possess a p-substituted phenol moiety and undergo oxidation into highly reactive and toxic o-quinone metabolites by tyrosinase.
Tomoko Nishimaki-Mogami +5 more
doaj +2 more sources
PD-L1+ neutrophils mediate immune regulation of CD8+ T cells in halo nevi [PDF]
BackgroundHalo nevi are clinically common and are characterized by a circle of leukoderma around the central melanocytic nevus. Studies have shown that the pathogenesis of halo nevi is similar to that of vitiligo and is associated with the role of CD8⁺ T
Yixuan Zhang +5 more
doaj +2 more sources
Comprehensive single-cell transcriptomic reveals different destinies of melanocytes and dynamic changes of immune microenvironment in a psychological stress-induced leukoderma and leukotrichia mouse model [PDF]
Background Vitiligo is an acquired skin depigmentation disorder often accompanied by leukoderma and leukotrichia. Half of vitiligo patients experience episodes of stress.
Xuechen Cao +9 more
doaj +2 more sources
Acral lentiginous melanoma with subsequent spontaneous vitiligo vulgaris: a case report and literature review [PDF]
Acral lentiginous melanoma (ALM) is an infrequent and often missed subtype of melanoma. Its association with spontaneous vitiligo vulgaris is an exceedingly rare condition. The current study presents a rare case of ALM with spontaneous vitiligo vulgaris
Ronak Saeed Ahmed +10 more
doaj +2 more sources
The many faces of autoimmune-mediated melanocyte destruction in melanoma [PDF]
Melanoma is the most severe form of skin cancer with an incidence that is increasing all over the world. Melanoma cells derive from normal melanocytes and share different melanocyte-specific antigens, the same antigens against which an immune reaction ...
Loredana Ungureanu +10 more
doaj +2 more sources
Evaluation of minced skin grafts in the treatment of post burn leukoderma. [PDF]
BackgroundPost burn leukoderma had been characterized by chalk white depigmented areas of variable sizes and shapes. Re-pigmentation of the hypopigmented lesion is still a big challenge, current treatment modalities for post burn leukoderma include non ...
Dawlat Emara +3 more
doaj +2 more sources
Bilateral Eyelash Poliosis with Raccoon Erythema and Hypopigmentation-Contact Follicular Leukoderma [PDF]
Shreya K Gowda +2 more
doaj +2 more sources
Sanqi, a traditional Chinese herb, is widely used for cardiovascular diseases, and its neuroprotective effects against oxidative stress were recently discovered. The purpose of this study was to investigate whether Sanqi-derived compound K (Sanqi-CK), an
Suwei Tang +6 more
doaj +1 more source

