Results 141 to 150 of about 1,799 (195)

Toxic leukoencephalopathies

Handbook of Clinical Neurology / Edited By P J Vinken and G W Bruyn
Toxic-metabolic encephalopathies are a group of disorders in which an exogenous or endogenous substance leads to transient or permanent neuronal damage. It is an important cause of potentially reversible acute encephalopathy syndrome. The signs and symptoms of toxic encephalopathies may be relatively nonspecific, and toxicologic tests are not always ...
Leandro Tavares Lucato, Gabriela Alencar Bandeira   +1 more
exaly   +3 more sources

Peroxisomal Leukoencephalopathy

Seminars in Neurology, 2012
Peroxisomal leukoencephalopathies include diseases belonging to the Zellweger spectrum and the rhizomelic chondrodysplasia punctata spectrum, as well as some single enzyme defects of peroxisomal β-oxidation. The authors present information on the clinical and diagnostic approach, and the characteristics of brain magnetic resonance imaging (MRI) in ...
Poll-The, Bwee Tien, Engelen, Marc
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Progressive Multifocal Leukoencephalopathy

CONTINUUM: Lifelong Learning in Neurology, 2008
Progressive multifocal leukoencephalopathy (PML) is an opportunistic viral infection of the human CNS that has gained new importance because of AIDS and newer immunosuppressive therapies. It destroys oligodendrocytes, leading to neurologic deficits associated with demyelination.PML most commonly occurs in patients who are HIV infected, but increasing ...
C, Arseni, F, Nerean tiu
  +8 more sources

Advances in the diagnosis of leukoencephalopathies

Expert Opinion on Medical Diagnostics, 2012
Introduction : Leukoencephalopathies (LEs) are a diverse group of diseases involving cerebral white matter. Some of the disorders may be infectious or immunologically mediated and, therefore, tend to be more amenable to treatment. Most of these disorders have a genetic basis, for which genetic counseling becomes important as currently very few of them ...
Doris D M Lin, Sakkubai Naidu
exaly   +3 more sources

Leukoencephalopathies in Adulthood

Seminars in Neurology, 2012
The understanding of the genetic basis of late-onset leukoencephalopathies has continued to increase in recent years. The most commonly presenting leukoencephalopathies in adulthood can be late-onset manifestations of metabolic pathways.
Jan-Mendelt, Tillema, Deborah L, Renaud
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Siblings With Leukoencephalopathy

Seminars in Pediatric Neurology, 2008
Two consanguineous siblings presented with developmental regression and emerging spasticity. Cranial magnetic resonance imaging in both showed diffuse leukoencephalopathy. Further investigation established the siblings as having complex 1 deficiency consequent to a novel homozygous mutation in NDUFV1, a nuclear-encoded subunit of complex 1.
Galen N, Breningstall, John, Shoffner, Richard J, Patterson   +2 more
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MRI in methotrexate-related leukoencephalopathy: Disseminated necrotising leukoencephalopathy in comparison with mild leukoencephalopathy

Neuroradiology, 2003
We report two fatal cases of methotrexate (MTX)-induced disseminated necrotising leukoencephalopathy (DNL) in which MRI was repeated from the onset. Initial T2-weighted images showed multiple areas of high signal, mainly in deep cerebral white matter, which on follow-up, spread and coalesced to involve the entire white matter.
M, Oka, S, Terae, R, Kobayashi, Y, Sawamura, K, Kudoh, K K, Tha, M, Yoshida, M, Kaneda, Y, Suzuki, K, Miyasaka   +9 more
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LEUKOENCEPHALOPATHIES AND LEUKODYSTROPHIES

Continuum, 2010
The leukoencephalopathies encompass a heterogeneous group of disorders that involve the brain white matter. The cause may be acquired or inherited; in the latter case, mutations have been found in genes that encode protein components of the myelin membrane or enzymes implicated in the turnover of myelin. In patients with cognitive dysfunction and white
openaire   +2 more sources

Toxic Leukoencephalopathies

Psychiatric Clinics of North America, 2011
Leukoencephalopathy is a syndrome of neurologic deficits, including alteration of mental status, caused by pathologic changes in the cerebral white matter. The term, toxic leukoencephalopathy, encompasses a wide variety of exposures and clinical presentations.
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Cree Leukoencephalopathy and Other Leukoencephalopathies Involving Arcuate Fibers

Radiology, 2001
Editor: We read with great interest the article by Dr Alorainy and colleagues in the November 1999 issue of Radiology (1). The authors nicely presented computed tomographic and magnetic resonance (MR) imaging findings of a rare and lethal disorder, Cree leukoencephalopathy, in 12 patients whose diagnoses were made clinically or at autopsy.
U, Senol, K, Karaali
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