Results 151 to 160 of about 1,799 (195)
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Leukoencephalopathies and metabolic diseases
Neurological Sciences, 2008Leukoencephalopathies and metabolic diseases comprise a great number of heterogeneous disorders. Diagnosis of these disorders may be challenging at times, requiring sophisticated laboratory investigations. Magnetic resonance imaging (MRI) is useful in supporting diagnosis even though it bears problems of specificity.
GIORGIO A., DE STEFANO N.
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Infectious leukoencephalopathies
Leukoencephalopathy from infectious agents may have a rapid course, such as human simplex virus encephalitis; however, in many diseases, it may take months or years before diagnosis, such as in subacute sclerosing panencephalitis or Whipple disease. There are wide geographic distributions and susceptible populations, including both immunocompetent and ...David, Jakabek +2 more
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2012
The white matter of the brain is vulnerable to a wide variety of toxins. Leukoencephalopathy is being increasingly recognized in a number of different patient populations. The detection of early and subtle toxin effects has been facilitated by the advent of magnetic resonance imaging, which offers better resolution of white matter than other ...
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The white matter of the brain is vulnerable to a wide variety of toxins. Leukoencephalopathy is being increasingly recognized in a number of different patient populations. The detection of early and subtle toxin effects has been facilitated by the advent of magnetic resonance imaging, which offers better resolution of white matter than other ...
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Progressive Multifocal Leukoencephalopathy
Seminars in Neurology, 1999Before the AIDS epidemic, progressive multifocal leukoencephalopathy (PML) was a rare disorder occurring most often in association with leukemia and lymphoma. Current estimates indicate that PML ultimately develops in up to 5% of all patients with AIDS.
J R, Berger, E O, Major
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Neurology, 2015
Just 11 years ago, a new genetic white matter disease, leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL), was described in 7 children and 1 teenager.1 Clinical features were dominated by progressive motor deterioration without sphincter dysfunction; half of the patients had loss of position and vibratory ...
Don, Gilden, Raphael, Schiffmann
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Just 11 years ago, a new genetic white matter disease, leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL), was described in 7 children and 1 teenager.1 Clinical features were dominated by progressive motor deterioration without sphincter dysfunction; half of the patients had loss of position and vibratory ...
Don, Gilden, Raphael, Schiffmann
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Concentric Lacunar Leukoencephalopathy
Archives of Neurology, 1960The group of diseases included under the general name of "leukoencephalopathy" comprises various pathoanatomic and pathogenic conditions. Their etiology is unknown. There is no satisfactory classification, and occasionally a new, equally obscure condition is added to this heterogeneous group. The purpose of this paper is to describe an unusual and not
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Intracarotid BCNU leukoencephalopathy
Cancer, 1986Intracarotid 1,3-bis(2-chloroethyl)-1-nitrosurea (BCNU) is now a frequently used chemotherapeutic agent for high-grade glial neoplasms. The toxicity from such therapy has not been well-documented. A 50-year-old man with a left frontoparietal grade 4 astrocytoma received three injections of intracarotid BCNU, 400 mg each, over a 2-month period.
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Progressive multifocal leukoencephalopathy
Journal of Neuroimmunology, 2011Progressive multifocal leukoencephalopathy (PML) is a disease of the central nervous system (CNS) with destructive infection of oligodendrocytes by JC virus. PML belongs to the opportunistic infections. It is observed in patients with HIV infection, lymphoid malignancies, after organ- and stem cell transplantations and more recently in the context of ...
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Progressive Multifocal Leukoencephalopathy
Neurologic Clinics, 1984PML is a progressive opportunistic infection of the CNS caused by a commonly occurring virus that may become manifest in the context of reduced host resistance in persons of any age. The authors review the disease and its causes, including a discussion of treatment attempts and differential diagnoses.
B R, Brooks, D L, Walker
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Progressive Multifocal Leukoencephalopathy
Archives of Internal Medicine, 1963Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating disease apparently resulting from the selective destruction of oligodendrocytes by papovaviruses. The pathology and pathogenesis of PML are distinct from those of the other slow infections of the human nervous system.
R F, JOHNSTON +2 more
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