Results 171 to 180 of about 21,234 (200)

Treatment of Progressive Multifocal Leukoencephalopathy with Pembrolizumab.

New England Journal of Medicine, 2019
Treatment of PML with Pembrolizumab A patient with variable immunodeficiency and progressive multifocal leukoencephalopathy was treated with five pembrolizumab infusions.
S. Rauer, R. Marks, H. Urbach, K. Warnatz, A. Nath, S. Holland, C. Weiller, B. Grimbacher   +7 more
semanticscholar   +1 more source

Serum neurofilaments increase at progressive multifocal leukoencephalopathy onset in natalizumab‐treated multiple sclerosis patients

Annals of Neurology, 2019
This study analyzed serum neurofilament light chains (NfL) in 2 European cohorts of 312 multiple sclerosis (MS) patients to investigate whether NfL are biomarkers of progressive multifocal leukoencephalopathy (PML) during natalizumab treatment.
G. Dalla Costa, V. Martinelli, L. Moiola, Francesca Sangalli, B. Colombo, A. Finardi, P. Cinque, Eva-Maria Kolb, A. Haghikia, R. Gold, R. Furlan, G. Comi   +11 more
semanticscholar   +1 more source

Progressive Multifocal Leukoencephalopathy

Journal of Computer Assisted Tomography, 1995
A case of progressive multifocal leukoencephalopathy (PML) with a classic clinical presentation but with unusual pathological and radiographic findings is reported. The pathology revealed evidence of prior hemorrhage, and imaging studies revealed focal cerebral atrophy as well as contrast enhancement on MR scans.
S, Ng, V C, Tse, J, Rubinstein, E, Bradford, D R, Enzmann, F K, Conley   +5 more
openaire   +2 more sources

The spectrum of progressive multifocal leukoencephalopathy: a practical approach

European Journal of Neurology, 2019
John Cunningham virus (JCV) infection of the central nervous system causes progressive multifocal leukoencephalopathy (PML) in patients with systemic immunosuppression.
T. Bartsch, T. Rempe, F. Leypoldt, C. Riedel, O. Jansen, Daniela Berg, G. Deuschl   +6 more
semanticscholar   +1 more source

Progressive Multifocal Leukoencephalopathy

New England Journal of Medicine, 1961
IN the course of the regular post-mortem examination of the brains of patients coming to autopsy at the Massachusetts General Hospital, my attention has been called in recent years to an unusual disorder of the cerebral white matter with distinctive features unfamiliar to me and my colleagues from our own experience or that of others.
openaire   +3 more sources

A case of progressive multifocal leukoencephalopathy under dimethyl fumarate treatment without severe lymphopenia or immunosenescence

Multiple Sclerosis, 2019
Background: Progressive multifocal leukoencephalopathy (PML) is the main safety concern for dimethyl fumarate (DMF) treatment in persons with multiple sclerosis (pwMS).
M. Diebold, V. Altersberger, B. Décard, L. Kappos, T. Derfuss, Johannes Lorscheider   +5 more
semanticscholar   +1 more source

[Progressive multifocal leukoencephalopathy].

Der Nervenarzt, 2016
Progressive multifocal leukoencephalopathy (PML) is a disease of immunosuppressed patients caused by the JC polyomavirus (JCPyV). Due to the elevated risk in patients treated with natalizumab for multiple sclerosis (MS) and also treatment with other biologicals for different indications, the relevance of PML has increased in recent years.
Warnke, C., Wattjes, M. P., Adams, O., Hartung, H. P., Martin, R., Weber, T., Stangel, M.   +6 more
openaire   +2 more sources

Natalizumab-associated progressive multifocal leukoencephalopathy in Germany

Neurology, 2019
Objective To evaluate characteristics relevant to diagnosis of JC polyomavirus-associated progressive multifocal leukoencephalopathy (PML), and PML risk stratification in a large national cohort of patients with multiple sclerosis during therapy with ...
Kira Blankenbach, N. Schwab, B. Hofner, O. Adams, B. Keller-Stanislawski, C. Warnke   +5 more
semanticscholar   +1 more source

Revisiting JC virus and progressive multifocal leukoencephalopathy

Journal of Neurovirology, 2023
Angela Rocchi, I. Sariyer, Joseph R. Berger   +2 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy

Neurology, 1965
R M, WOOLSEY, J S, NELSON
openaire   +4 more sources