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Progressive Multifocal Leukoencephalopathy
Seminars in Neurology, 1999Before the AIDS epidemic, progressive multifocal leukoencephalopathy (PML) was a rare disorder occurring most often in association with leukemia and lymphoma. Current estimates indicate that PML ultimately develops in up to 5% of all patients with AIDS.
Joseph R Berger, Eugene O Major
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Progressive Multifocal Leukoencephalopathy
Neurologic Clinics, 1984PML is a progressive opportunistic infection of the CNS caused by a commonly occurring virus that may become manifest in the context of reduced host resistance in persons of any age. The authors review the disease and its causes, including a discussion of treatment attempts and differential diagnoses.
B R, Brooks, D L, Walker
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Progressive Multifocal Leukoencephalopathy
European Neurology, 1971The present paper reports on a case of progressive multifocal leukoencephalopathy, with certain particularities.
C, Arseni, F, Nerean tiu
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Progressive Multifocal Leukoencephalopathy
Archives of Internal Medicine, 1963Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating disease apparently resulting from the selective destruction of oligodendrocytes by papovaviruses. The pathology and pathogenesis of PML are distinct from those of the other slow infections of the human nervous system.
R F, JOHNSTON +2 more
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Progressive Multifocal Leukoencephalopathy
Radiology, 1976The radionuclide, radiographic and pathologic findings in a patient with progressive multifocal leukoencephalopathy were correlated. Radionuclide imaging demonstrated the largest two of the many lesions observed at pathology. On repeated studies, one of the lesions developed a "doughnut" sign due to central necrosis. Cerebral angiography disclosed only
J, Kirsh +3 more
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Progressive multifocal leukoencephalopathy
Current Infectious Disease Reports, 2001Progressive multifocal leukoencephalopathy is a subacute demyelinating disease that occurs in patients with defects in cell-mediated immunity, including those with AIDS and lymphoproliferative disorders. It is caused by reactivation of JC virus (JCV), which infects 70% to 90% of the population by adulthood, but remains latent in normal hosts.
Anna R., Thorner, Joel T., Katz
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Progressive Multifocal Leukoencephalopathy
Archives of Ophthalmology, 1959Astrom, Mancall, and Richardson1have recently directed attention to progressive multifocal leukoencephalopathy, a previously unrecognized neuropathological entity. Visual symptoms have been prominent in this disorder. As no cases have been reported in the ophthalmologic literature, the following instance of progressive multifocal leukoencephalopathy ...
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