Results 51 to 60 of about 23,690 (177)
International Journal of General Medicine, 2020 Jie Chen,1 Shiying Luo,1 Ning Li,1 Huimin Li,1 Jinming Han,2 Li Ling1 1Department of Neurology, Affiliated Hospital of Hebei University, Baoding, People’s Republic of China; 2Department of Clinical Neuroscience, Karolinska Institutet, Stockholm ...
Chen J, Luo S, Li N, Li H, Han J, Ling L
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The FEBS Journal, EarlyView.NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu +9 more
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Psychotherapy and inhibitory control: Insights from fMRI research
Psychiatry and Clinical Neurosciences, EarlyView.Aim Despite the widespread clinical use of psychotherapy, the neural mechanisms linking treatment to changes in inhibitory control networks supporting self‐regulation remain unclear. This study addresses this gap by meta‐analyzing neuroimaging research on how psychotherapy affects brain regions involved in inhibitory control.
Gioele Gavazzi +5 more
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The Journal of Physiology, EarlyView.Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
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PLoS ONEBackgroundCSF1R-related leukoencephalopathy is a type of autosomal dominant leukodystrophy caused by mutations in the colony stimulating factor 1 receptor (CSF1R) gene.
Seung Joo Kim +10 more
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Asymptomatic progressive multifocal leukoencephalopathy: a case report and review of the literature
Journal of Medical Case Reports, 2018 Background We report the development of asymptomatic progressive multifocal leukoencephalopathy in a patient with multiple sclerosis on natalizumab therapy.
Yinan Zhang +2 more
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Posterior leukoencephalopathy syndrome [PDF]
Postgraduate Medical Journal, 2001 Abstract Posterior leukoencephalopathy syndrome is a newly recognised brain disorder that predominantly affects the cerebral white matter. Oedematous lesions particularly involve the posterior parietal and occipital lobes, and may spread to basal ganglia, brain stem, and cerebellum.
openaire +2 more sources
Inflammatory Mediators Both Directly and Indirectly Promote Microglial Proliferation
Glia, Volume 74, Issue 5, May 2026.– CSF2, IL3, and TNFɑ directly promote microglial proliferation. – Neuron‐secreted factors suppress microglial proliferation. – IL1 cytokines promote CSF2 release from astrocytes, which promotes microglial proliferation. ABSTRACT Microglia—the predominant immune cell of the central nervous system (CNS)—possess an astounding capacity for proliferation ...
Brady P. Hammond +4 more
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An Unusual Motor OFF in Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.
Shreyashi Jha, Mandar S. Jog
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Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu +20 more
wiley +1 more source