Results 51 to 60 of about 32,319 (241)

A homozygous mutation of alanyl‐transfer RNA synthetase 2 in a patient of adult‐onset leukodystrophy: A case report and literature review

Brain and Behavior, 2019
Introduction Leukodystrophy is a group of hereditary leukoencephalopathies predominantly affecting the white matter. Multiple genes and mutations have been reported to be associated with this disorder.
Jian‐Yong Wang, Song‐Fang Chen, Hong‐Qiu Zhang, Meng‐Yan Wang, Jian‐Hong Zhu, Xiong Zhang   +5 more
doaj   +1 more source

Diabetes, leukoencephalopathy and rage

Neurobiology of Disease, 2006
Longstanding diabetes mellitus damages kidney, retina, peripheral nerve and blood vessels, but brain is not usually considered a primary target. We describe direct involvement of the brain, particularly white matter, in long-term (9 months) experimental diabetes of mice, not previously modeled, correlating magnetic resonance (MR) imaging with ...
Toth, C, Schmidt, A, Tuor, U, Francis, G, Foniok, T, Brussee, V, Kaur, J, Yan, S, Martinez, J, Barber, P, Buchan, A, Zochodne, D   +11 more
openaire   +3 more sources

From Uncertainty to Pathogenicity: Resolving a CSF1R Variant of Uncertain Significance Using Long‐Read Transcriptomics

Movement Disorders, EarlyView.
Abstract Background CSF1R‐related disorder (CSF1R‐RD) is a severe autosomal dominant leukoencephalopathy characterized by progressive cognitive, neuropsychiatric, and motor decline. Although genetic testing is widely available, numerous likely pathogenic variants in CSF1R frequently remain classified as variants of uncertain significance (VUS ...
Charles Wade, Kylie Montgomery, Gabriela E. Jones, Peter Sellars, Akram A. Hosseini, Simon Paine, Henry Houlden, Mina Ryten, David S. Lynch   +8 more
wiley   +1 more source

Delayed Leukoencephalopathy: A Rare Complication after Coiling of Cerebral Aneurysms [PDF]

, 2020
Background and purposeDelayed leukoencephalopathy is a rare complication that occurs after endovascular coiling of cerebral aneurysms. We aimed to describe a clinical picture of delayed leukoencephalopathy and explore potential associations with ...
Ikemura, A, Ishibashi, T, Otani, K, Kato, N, Kan, I, Murayama, Y, Kodama, T, Yuki, I   +7 more
core   +1 more source

Magnetic resonance imaging in HTLV-I associated myelopathy Ressonância magnética na mielopatia associada ao HTLV-I

Arquivos de Neuro-Psiquiatria, 1993
Magnetic resonance imaging of the brain and spinal cord were carried out for seventeen consecutive patients with HTLV-1 associated myelopathy (HAM). Eight patients had brain abnormalities and four had decreased thoracic spinal cord diameter.
Aílton Melo, Luciana Moura, Solana Rios, Marcos Machado, Gersonita Costa   +4 more
doaj  

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

Reversible posterior leukoencephalopathy induced by cancer chemotherapy

, 2010
Reversible posterior leukoencephalopathy, defined by both clinical and neuroimaging findings, can affect children receiving chemotherapy. The syndrome is characterized by hypertension, alterations in mental status, seizures, hallucinations, and acute ...

core   +1 more source

Unilateral Leukoencephalopathy Revealing Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

, 2022
International audienceCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an autosomal dominant genetic microangiopathy whose symptoms include migraine with aura, lacunar cerebral infarcts, and mood ...
Morel, Hélène, Cédric Gollion, Bonneville, Fabrice, Fabrice Bonneville, Hélène Morel, Gollion, Cédric   +5 more
core   +1 more source

Gyriform Susceptibility Rim in Early Progressive Multifocal Leukoencephalopathy

Annals of Neurology, EarlyView.
Thor Linnet, Karan Dixit, Shailee Shah
wiley   +1 more source

Irreversible Leukoencephalopathy in a Chinese Renal Transplant Recipient [PDF]

, 2010
Tacrolimus is an immunosuppressive agent that can show a wide variety of neurological side effects, including leukoencephalopathy. The prognosis is usually good with complete neurological recovery after dose reduction or cessation.
Chau, Ka Foon, Ka Foon Chau, Tang, Kwok Wing, Li, Chun Sang, Kwok Wing Tang, Wing Chi Fong, Chun Sang Li, Cheung, Chi Yuen, Fong, Wing Chi, Chi Yuen Cheung   +9 more
core   +1 more source