Results 51 to 60 of about 4,419 (217)

Pathogenesis of diabetic macular edema: the role of pro-inflammatory and vascular factors. A literature review

Mìžnarodnij Endokrinologìčnij Žurnal, 2022
The review presents data on the pathogenesis of diabetic macular edema (DME). DME is a major cause of visual impairment in type 2 diabetes mellitus (DM) patients. Non-specific inflammation is an important factor of the underlying processes of DME.
M.L. Kyryliuk, S.A. Suk
doaj   +1 more source

Congenital leukemia presenting as fever in a neonate [PDF]

, 2015
Background Emergency department workup of pediatric fever typically focuses on ruling out serious bacterial infection, but other disease processes can cause fever. Congenital leukemia is a rare but important cause of fever in neonates.
Beard, Bethany, Turner, Joseph
core   +1 more source

Alterations to the Blood-Retinal Barrier in Diabetes: Cytokines and Reactive Oxygen Species [PDF]

, 2011
Diabetic retinopathy (DR) is a leading cause of blindness in Western society. Since the prevalence of diabetes continues to increase dramatically, the impact of DR will only worsen unless new therapeutic options are developed.
Antonetti, David A., Frey, Tiffany
core   +1 more source

Chronic Myeloid Leukemia Presenting With T‐Lymphoid Blast Crisis in a Young Female With Marked Hyperleukocytosis: A Case Report

eJHaem, Volume 7, Issue 2, April 2026.
Abstract Background Chronic myeloid leukemia (CML) presenting in blast crisis (BC) is uncommon in the era of tyrosine kinase inhibitor (TKI) treatment, and T‐lymphoblastic BC is exceptionally rare. We report a case of T‐lymphoid BC presenting with extreme hyperleukocytosis.
E. Somasundaram, R. P. Hasserjian, B. J. Aubrey, A. T. Fathi, H. Hock   +4 more
wiley   +1 more source

The biomechanics of drug-treated leukemia cells investigated using optical tweezers [PDF]

, 2012
Leukemia is a very common cancer worldwide, and different drugs have been applied to treat the disease. However, the influence of the drugs on the biomechanical properties of leukemia cells, which are related to the risk of leukostasis, is still unknown.
Ngan, AHW, Tang, B, Zhou, ZL
core   +1 more source

Hyperleukocytosis and Access to Minimal Residual Disease Testing Impact Outcomes in Children With Newly Diagnosed Acute Myeloid Leukemia in Thailand

Pediatric Blood &Cancer, Volume 73, Issue 3, March 2026.
ABSTRACT Background The survival outcomes among children with acute myeloid leukemia (AML) in low‐ and middle‐income countries are still poor despite adopting modern treatment regimens from developed countries. The study aimed to identify additional potential determinant factors for relapse and death among children with AML in Thailand. Methods In all,
Piya Rujkijyanont, Supak Ukritchon, Angkana Winaichatsak, Pitchayanan Kuwatjanakul, Thirachit Chotsampancharoen, Piti Techavichit, Su‐on Chainansamit, Lalita Sathitsamitphong, Kittima Kanchanakamhaeng, Usanarat Anurathapan, Napat Laoaroon, Chonthida Wangkittikal, Chalinee Monsereenusorn, Watinee Sanpote, Nattaporntira Phalakornkul, Pariwan Sripattanatadasakul, Daranee Isaranimitkul, Pokpong Na Songkhla, Phakatip Sinlapamongkolkul, Jassada Buaboonnam, Samart Pakakasama   +20 more
wiley   +1 more source

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, Volume 58, Issue 2, Page 619-629, March 2026.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Emma H. Hooijberg, Amelia Goddard   +2 more
wiley   +1 more source

Glycocalyx Degradation in Retinal and Choroidal Capillary Endothelium in Rats with Diabetes and Hypertension [PDF]

, 2010
Endothelial glycocalyx (GCX) has been reported as a protective factor for vascular endothelial cells (VEC) in diabetes and hypertension. However, the involvement of GCX impairment in ocular vasculopathy remains unclear.
Kumase, Fumiaki, Mohri, Satoshi, Morizane, Yuki, Ohtsuka, Aiji, Ohtsuki, Hiroshi, Takasu, Ippei   +5 more
core   +1 more source

Prevalence, Risk Factors, and Prognostic Impact of Spontaneous Tumor Lysis Syndrome in Aggressive Hematologic Malignancies: Experience From the Clinical Hematology Department, University of Dakar

Advances in Hematology, Volume 2026, Issue 1, 2026.
Spontaneous tumor lysis syndrome (sTLS) is a life‐threatening oncometabolic emergency that remains poorly documented in low‐resource settings. This retrospective cohort study aimed to assess the prevalence, risk factors, and prognostic implications of sTLS in adults with aggressive hematologic malignancies in Dakar, Senegal.
Alioune Badara Diallo, Blaise Félix Faye, Sokhna Aissatou Touré, Elimane Seydi Bousso, Mohamed Keita, Fatma Dieng, Moussa Seck, Saliou Diop, Kalyani Sen   +8 more
wiley   +1 more source

Long term impact of hyperleukocytosis in newly diagnosed acute myeloid leukemia patients undergoing allogeneic stem cell transplantation : An analysis from the acute leukemia working party of the EBMT [PDF]

, 2017
Up to 20% of acute myeloid leukemia (AML) patients present initially with hyperleukocytosis, placing them at increased risk for early mortality during induction. Yet, it is unknown whether hyperleukocytosis still retains prognostic value for AML patients
Blaise, Didier, Bourhis, Jean H., Canaani, Jonathan, Chevallier, Patrice, Cornelissen, Jan, Deconinck, Eric, Forcade, Edouard, Gedde-Dahl, Tobias, Huynh, Anne, Labopin, Myriam, Mohty, Mohamad, Nagler, Arnon, Nihtinen, Anne, Socie, Gerard   +13 more
core   +1 more source