Results 101 to 110 of about 3,520 (213)

Concordance in diagnostic testing for respiratory pathogens of bighorn sheep

Wildlife Society Bulletin, 2016
Reliable diagnostic tests are essential for disease investigation and management. This is particularly true for diseases of free‐ranging wildlife where sampling is logistically difficult precluding retesting.
Daniel P. Walsh, E. Frances Cassirer, Michael D. Bonds, Daniel R. Brown, William H. Edwards, Glen C. Weiser, Mark L. Drew, Robert E. Briggs, Karen A. Fox, Michael W. Miller, Sudarvili Shanthalingam, Subramaniam Srikumaran, Thomas E. Besser   +12 more
doaj   +1 more source

Role of carriers in the transmission of pneumonia in bighorn sheep (Ovis canadensis)

Biology Open, 2016
In the absence of livestock contact, recurring lamb mortality in bighorn sheep (Ovis canadensis) populations previously exposed to pneumonia indicates the likely presence of carriers of pneumonia-causing pathogens, and possibly inadequate maternally ...
Bindu Raghavan, Kayla Erickson, Abirami Kugadas, Sai A. Batra, Douglas R. Call, Margaret A. Davis, William J. Foreyt, Subramaniam Srikumaran   +7 more
doaj   +1 more source

A chimeric protein comprising the immunogenic domains of Mannheimia haemolytica leukotoxin and outer membrane protein PlpE induces antibodies against leukotoxin and PlpE

, 2016
Mannheimia haemolytica is a very important pathogen of pneumonia in ruminants. Bighorn sheep (BHS, Ovis canadensis) are highly susceptible to M. haemolytica-caused pneumonia which has significantly contributed to the drastic decline of bighorn sheep ...
Batra, Sai Arun, Shanthalingam, Sudarvili, Srikumaran, Subramaniam, DONOFRIO, Gaetano   +3 more
core   +1 more source

Effects of Aggregatibacter actinomycetemcomitans leukotoxin on neutrophil migration and extracellular trap formation

Journal of Oral Microbiology, 2016
Background: Aggressive periodontitis is associated with the presence of Aggregatibacter actinomycetemcomitans, a leukotoxin (Ltx)-producing periodontal pathogen. Ltx has the ability to lyse white blood cells including neutrophils.
Josefine Hirschfeld, Helen M. Roberts, Iain L. C. Chapple, Marijo Parčina, Søren Jepsen, Anders Johansson, Rolf Claesson   +6 more
doaj   +1 more source

Protective epitopes in the leukotoxin of Pasteurella haemolytica

, 1993
Pasteurella haemolytica Al has been implicated as a causative agent in shipping fever pneumonia. This organism produces a potent leukotoxin which is thought to promote inflammation and potentiate bacterial proliferation in the lungs of infected animals ...
Fish, Elizabeth D.
core  

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides

Journal of Lipid Research, 2004
CYP4F isoforms are involved in the oxidation of important cellular mediators such as leukotriene B4 (LTB4) and prostaglandins. The proinflammatory agent LTB4 and cytotoxic leukotoxins have been associated with several inflammatory diseases.
Valérie Le Quéré, Emmanuelle Plée-Gautier, Philippe Potin, Stéphanie Madec, Jean-Pierre Salaün   +4 more
doaj   +1 more source

[Leukotoxin and pulmonary injury].

Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1990
In spite of the development of various antibiotics, management of elderly patients with pneumonia remains an important problem. It is suggested that adult respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC) often occur in elderly patients with pneumonia.
S, Sugiyama, M, Hayakawa, Y, Hanaki, T, Ogawa, T, Ozawa   +4 more
openaire   +1 more source

Identification and expression of the Actinobacillus actinomycetemcomitans leukotoxin gene

Biochemical and Biophysical Research Communications, 1989
The leukotoxin produced by the oral bacterium Actinobacillus actinomycetemcomitans has been implicated in the pathogenesis of juvenile periodontitis. In order to elucidate the structure of the leukotoxin, molecular cloning of the leukotoxin gene was carried out. A DNA library of A. actinomycetemcomitans, strain JP2, was constructed by partial digestion
E T, Lally, I R, Kieba, D R, Demuth, J, Rosenbloom, E E, Golub, N S, Taichman, C W, Gibson   +6 more
openaire   +2 more sources

Generation of monoclonal antibodies to Pasteurella haemolytica leukotoxin : characterization of a neutralizing monoclonal antibody

, 1991
Pasteurella haemolytica produces a potent leukotoxin that is believed to play a major role in bovine pneumonic pasteurellosis. Very little is understood regarding the antigenic and functional domains of the leukotoxin molecule.
Gerbig, Donald G.
core  

Heterogeneity of Size and Toxin Distribution in Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles

Toxins
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium associated with localized aggressive periodontitis as well as some systemic diseases. The strains of A.
Justin B Nice, Shannon M. Collins, Samuel M. J. Agro, Anxhela Sinani, Spencer D. Moros, Leah M. Pasch, Angela C. Brown   +6 more
doaj   +1 more source