Results 81 to 90 of about 2,921 (175)
Necrotizing pneumonia and empyema caused by Fusobacterium necrophorum are uncommon. The classical presentation of Lemierre′s syndrome, characterized by pharyngotonsillitis and internal jugular vein thrombosis, is not always observed, and incomplete and atypical variants can cause diagnostic uncertainty and delay in treatment.
Deborah Shefa +7 more
wiley +1 more source
Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells
Aggregatibacter actinomycetemcomitans is a human pathogen that produces leukotoxin (LtxA) as a major virulence factor. In this study the effect of LtxA on microvascular endothelial cell viability and phenotype was studied. High doses of single LtxA treatment (500 ng/ml to 5 μg/ml) significantly and irreversibly decreased cell proliferation and induced ...
Dietmann, Anelia +5 more
openaire +2 more sources
Staphylococcus aureus is a leading cause of foodborne diarrhea, primarily due to staphylococcal enterotoxins (SEs). This study employed whole‐genome sequencing to characterize 106 S. aureus isolates from diarrheal patients in East China (2019–2024). We identified 23 sequence types, with ST398 (22.6%) and ST5 (7.5%) among the most prevalent.
Jinzhi Zhang +7 more
wiley +1 more source
Periodontal Ecosystem and Clinical Implications of the Oral Microbiome: A Narrative Review
Background Periodontal disease, although widely documented, remains one of the leading causes of tooth loss worldwide. This situation can be attributed to patients’ difficulty in following treatment protocols and to an incomplete understanding of the disease’s mechanisms, which could be explored to develop new therapies.
Ana Júlia Martins Targino +5 more
wiley +1 more source
Concordance in diagnostic testing for respiratory pathogens of bighorn sheep
Reliable diagnostic tests are essential for disease investigation and management. This is particularly true for diseases of free‐ranging wildlife where sampling is logistically difficult precluding retesting.
Daniel P. Walsh +12 more
doaj +1 more source
Role of carriers in the transmission of pneumonia in bighorn sheep (Ovis canadensis)
In the absence of livestock contact, recurring lamb mortality in bighorn sheep (Ovis canadensis) populations previously exposed to pneumonia indicates the likely presence of carriers of pneumonia-causing pathogens, and possibly inadequate maternally ...
Bindu Raghavan +7 more
doaj +1 more source
Salivary multiomics from healthy, PD, RA, and PD‐RA cohorts identified PD−/RA‐linked microbial and metabolic signatures. We then transplanted salivary microbiota from a PD donor or a healthy donor into collagen‐induced arthritis mice. PD microbiota colonized the gut, reshaped communities, weakened epithelial tight junctions, and provoked systemic ...
Ruiyang Ge +9 more
wiley +1 more source
Background: Aggressive periodontitis is associated with the presence of Aggregatibacter actinomycetemcomitans, a leukotoxin (Ltx)-producing periodontal pathogen. Ltx has the ability to lyse white blood cells including neutrophils.
Josefine Hirschfeld +6 more
doaj +1 more source
Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides
CYP4F isoforms are involved in the oxidation of important cellular mediators such as leukotriene B4 (LTB4) and prostaglandins. The proinflammatory agent LTB4 and cytotoxic leukotoxins have been associated with several inflammatory diseases.
Valérie Le Quéré +4 more
doaj +1 more source
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium associated with localized aggressive periodontitis as well as some systemic diseases. The strains of A.
Justin B Nice +6 more
doaj +1 more source

