Results 61 to 70 of about 3,055 (179)
Aggregatibacter actinomycetemcomitans, the focus of this review, was initially proposed as a microbe directly related to a phenotypically distinct form of periodontitis called localized juvenile periodontitis.
Daniel H. Fine +2 more
doaj +1 more source
Full‐length 16S and 18S rRNA Oxford Nanopore sequencing of large intestine contents from 30 healthy European brown hares revealed broad gut microbiome diversity. An 80% identity threshold detected substantially greater taxonomic richness than 95%, emphasizing the value of long‐read sequencing in wildlife microbiome research. ABSTRACT The European brown
Zbigniew Bełkot +7 more
wiley +1 more source
Secretion of RTX Leukotoxin by Actinobacillus actinomycetemcomitans [PDF]
ABSTRACT Actinobacillus actinomycetemcomitans , the etiologic agent for localized juvenile periodontitis and certain other human infections, such as endocarditis, expresses a leukotoxin that acts on polymorphonuclear leukocytes and macrophages.
S C, Kachlany, D H, Fine, D H, Figurski
openaire +2 more sources
ABSTRACT This case report describes a novel presentation of Aggregatibacter actinomycetemcomitans causing deep neck abscess, mediastinitis, and deep vein thrombosis. Clinicians should be aware that this organism can cause invasive extra‐oral infection.
Joshua Sia, Carly Hughes
wiley +1 more source
Clostridium perfringens causes a wide range of diseases in a variety of hosts, due to the production of a diverse set of toxins and extracellular enzymes. The C.
Jake A. Lacey +3 more
doaj +1 more source
Oral microbiota: findings, classification, clinical significance, and therapeutic interventions for human systemic diseases ABSTRACT The oral microbiota is an ecological community of commensal, symbiotic, and pathogenic microorganisms that colonizes the oral cavity.
Miao Zhang +13 more
wiley +1 more source
Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells
Aggregatibacter actinomycetemcomitans is a human pathogen that produces leukotoxin (LtxA) as a major virulence factor. In this study the effect of LtxA on microvascular endothelial cell viability and phenotype was studied. High doses of single LtxA treatment (500 ng/ml to 5 μg/ml) significantly and irreversibly decreased cell proliferation and induced ...
Dietmann, Anelia +5 more
openaire +2 more sources
Regulation of expression of the Pasteurella haemolytica leukotoxin determinant [PDF]
The Pasteurella haemolytica leukotoxin determinant is composed of four contiguous genes encoded on the same DNA strand and denoted lktCABD, in the order of their genetic organization. To gain a better understanding of the expression and regulation of the leukotoxin, the transcripts and promoters of the lkt determinant were mapped.
C A, Strathdee, R Y, Lo
openaire +2 more sources
Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans
Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity of a large proportion of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade inflammation ...
Georgios N. Belibasakis +7 more
doaj +1 more source
Background Lemierre’s syndrome is a rare but potentially life‐threatening condition traditionally characterized by bacteremia, septic thrombophlebitis of the internal jugular vein, and metastatic septic emboli following pharyngotonsillitis. We report an atypical presentation originating from submandibular sialadenitis and complicated by external ...
Sara Torretta +3 more
wiley +1 more source

