Results 71 to 80 of about 2,921 (175)

The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS

open access: yesJournal of Lipid Research, 2002
A method for the simultaneous quantification of urinary linoleic and arachidonic acid derived epoxides and diols, as well as the arachidonate omega hydroxylated product has been developed. The method employs negative mode electrospray ionization and HPLC
John W. Newman   +2 more
doaj   +1 more source

Aggregatibacter, A Low Abundance Pathobiont That Influences Biogeography, Microbial Dysbiosis, and Host Defense Capabilities in Periodontitis: The History of A Bug, And Localization of Disease

open access: yesPathogens, 2020
Aggregatibacter actinomycetemcomitans, the focus of this review, was initially proposed as a microbe directly related to a phenotypically distinct form of periodontitis called localized juvenile periodontitis.
Daniel H. Fine   +2 more
doaj   +1 more source

Full‐Length 16S and 18S rRNA Long‐Read Sequencing Reveals Gut Microbiome Diversity in the European Brown Hare (Lepus europaeus)

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Full‐length 16S and 18S rRNA Oxford Nanopore sequencing of large intestine contents from 30 healthy European brown hares revealed broad gut microbiome diversity. An 80% identity threshold detected substantially greater taxonomic richness than 95%, emphasizing the value of long‐read sequencing in wildlife microbiome research. ABSTRACT The European brown
Zbigniew Bełkot   +7 more
wiley   +1 more source

Deep Tracking Neck Abscesses, Mediastinitis, and Deep Vein Thrombosis Caused by Aggregatibacter actinomycetemcomitans

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT This case report describes a novel presentation of Aggregatibacter actinomycetemcomitans causing deep neck abscess, mediastinitis, and deep vein thrombosis. Clinicians should be aware that this organism can cause invasive extra‐oral infection.
Joshua Sia, Carly Hughes
wiley   +1 more source

In silico Identification of Novel Toxin Homologs and Associated Mobile Genetic Elements in Clostridium perfringens

open access: yesPathogens, 2019
Clostridium perfringens causes a wide range of diseases in a variety of hosts, due to the production of a diverse set of toxins and extracellular enzymes. The C.
Jake A. Lacey   +3 more
doaj   +1 more source

Oral Microbiota: Findings, Classification, Clinical Significance, and Therapeutic Interventions for Human Systemic Diseases

open access: yesiMetaMed, Volume 2, Issue 1, March 2026.
Oral microbiota: findings, classification, clinical significance, and therapeutic interventions for human systemic diseases ABSTRACT The oral microbiota is an ecological community of commensal, symbiotic, and pathogenic microorganisms that colonizes the oral cavity.
Miao Zhang   +13 more
wiley   +1 more source

Aggregatibacter actinomycetemcomitans Leukotoxin [PDF]

open access: yesJournal of Dental Research, 2010
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that colonizes the human oral cavity and is the causative agent for localized aggressive periodontitis (LAP), an aggressive form of periodontal disease that occurs in adolescents. A. actinomycetemcomitans secretes a protein toxin, leukotoxin (LtxA), which helps the bacterium evade the ...
openaire   +2 more sources

Regulation of expression of the Pasteurella haemolytica leukotoxin determinant [PDF]

open access: yesJournal of Bacteriology, 1989
The Pasteurella haemolytica leukotoxin determinant is composed of four contiguous genes encoded on the same DNA strand and denoted lktCABD, in the order of their genetic organization. To gain a better understanding of the expression and regulation of the leukotoxin, the transcripts and promoters of the lkt determinant were mapped.
C A, Strathdee, R Y, Lo
openaire   +2 more sources

Are leukotoxins toxic? [PDF]

open access: yesNature Medicine, 1997
Takeshi Ishizaki   +2 more
openaire   +2 more sources

Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans

open access: yesPathogens, 2019
Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity of a large proportion of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade inflammation ...
Georgios N. Belibasakis   +7 more
doaj   +1 more source

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