Results 71 to 80 of about 3,520 (213)

Full‐Length 16S and 18S rRNA Long‐Read Sequencing Reveals Gut Microbiome Diversity in the European Brown Hare (Lepus europaeus)

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Full‐length 16S and 18S rRNA Oxford Nanopore sequencing of large intestine contents from 30 healthy European brown hares revealed broad gut microbiome diversity. An 80% identity threshold detected substantially greater taxonomic richness than 95%, emphasizing the value of long‐read sequencing in wildlife microbiome research. ABSTRACT The European brown
Zbigniew Bełkot, Mateusz G. Adamski, Zuzanna J. Strzałkowska, Ewa D. Domańska, Daria Kłosińska, Grzegorz Kunstman, Dawid Skoczek, Joanna Pławińska‐Czarnak   +7 more
wiley   +1 more source

Secretion of RTX Leukotoxin by Actinobacillus actinomycetemcomitans [PDF]

Infection and Immunity, 2000
ABSTRACT Actinobacillus actinomycetemcomitans , the etiologic agent for localized juvenile periodontitis and certain other human infections, such as endocarditis, expresses a leukotoxin that acts on polymorphonuclear leukocytes and macrophages.
S C, Kachlany, D H, Fine, D H, Figurski
openaire   +2 more sources

Deep Tracking Neck Abscesses, Mediastinitis, and Deep Vein Thrombosis Caused by Aggregatibacter actinomycetemcomitans

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT This case report describes a novel presentation of Aggregatibacter actinomycetemcomitans causing deep neck abscess, mediastinitis, and deep vein thrombosis. Clinicians should be aware that this organism can cause invasive extra‐oral infection.
Joshua Sia, Carly Hughes
wiley   +1 more source

Aggregatibacter actinomycetemcomitans Leukotoxin [PDF]

Journal of Dental Research, 2010
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that colonizes the human oral cavity and is the causative agent for localized aggressive periodontitis (LAP), an aggressive form of periodontal disease that occurs in adolescents. A. actinomycetemcomitans secretes a protein toxin, leukotoxin (LtxA), which helps the bacterium evade the ...
openaire   +2 more sources

Lipopolysaccharide Complexes withPasteurella haemolyticaLeukotoxin [PDF]

Infection and Immunity, 1999
ABSTRACTThe presence of lipopolysaccharide (LPS) in gram-negative bacterial repeats-in-toxin (RTX) toxin preparations, as well as the harsh conditions required to remove it, suggests that LPS may complex with RTX toxins. Concentrated culture supernatant (CCS) preparations of the RTX toxinPasteurella haemolyticaleukotoxin (LKT) contained LKT and LPS as ...
J, Li, K D, Clinkenbeard
openaire   +2 more sources

The Extracellular Domain of the β₂ Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity

mBio, 2019
The Escherichia coli hemolysin (HlyA) is a pore-forming exotoxin associated with severe complications of human urinary tract infections. HlyA is the prototype of the repeats-in-toxin (RTX) family, which includes LtxA from Aggregatibacter ...
Laura C. Ristow, Vy Tran, Kevin J. Schwartz, Lillie Pankratz, Andrew Mehle, John-Demian Sauer, Rodney A. Welch   +6 more
doaj   +1 more source

Oral Microbiota: Findings, Classification, Clinical Significance, and Therapeutic Interventions for Human Systemic Diseases

iMetaMed, Volume 2, Issue 1, March 2026.
Oral microbiota: findings, classification, clinical significance, and therapeutic interventions for human systemic diseases ABSTRACT The oral microbiota is an ecological community of commensal, symbiotic, and pathogenic microorganisms that colonizes the oral cavity.
Miao Zhang, Meihang Du, Wenjiang Zhang, Renhuan Huang, Wanting Li, Tongqi Li, Junping Bai, Ning Zhang, Jungang Chen, Jing Zhou, Bing Wang, Liwei An, Hideaki Kagami, Yiming Zhang   +13 more
wiley   +1 more source

Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells

Microbial Pathogenesis, 2013
Aggregatibacter actinomycetemcomitans is a human pathogen that produces leukotoxin (LtxA) as a major virulence factor. In this study the effect of LtxA on microvascular endothelial cell viability and phenotype was studied. High doses of single LtxA treatment (500 ng/ml to 5 μg/ml) significantly and irreversibly decreased cell proliferation and induced ...
Dietmann, Anelia, Millonig, Alban, Combes, Valery, Couraud, Pierre-Olivier, Kachlany, Scott C., Grau, Georges E.   +5 more
openaire   +2 more sources

Transmembrane pore size and role of cell swelling in cytotoxicity caused by Pasteurella haemolytica leukotoxin

, 1989
Pasteurella haemolytica A1 leukotoxin causes rapid (5 to 15 min) leakage of intracellular K+ and cell swelling and slower (15 to 60 min), Ca2+-dependent formation of large plasma membrane defects (~100 nm) and leakage of lactate dehydrogenase from bovine
Clinkenbeard, Kenneth D., Mosier, Derek A., Confer, Anthony W.   +2 more
core   +1 more source

Severe Necrotizing Community‐Acquired Pneumonia and Bilateral Empyema in an Immunocompetent Patient due to Fusobacterium necrophorum

Case Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Necrotizing pneumonia and empyema caused by Fusobacterium necrophorum are uncommon. The classical presentation of Lemierre′s syndrome, characterized by pharyngotonsillitis and internal jugular vein thrombosis, is not always observed, and incomplete and atypical variants can cause diagnostic uncertainty and delay in treatment.
Deborah Shefa, Aryan Shiari, Marina Antic, Buddhi P. Hatharaliyadda, Juan Vera Gomez, David Ladin, Igor Dumic, Tun-Chieh Chen   +7 more
wiley   +1 more source