Results 71 to 80 of about 3,055 (179)

Aggregatibacter actinomycetemcomitans Leukotoxin [PDF]

open access: yesJournal of Dental Research, 2010
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium that colonizes the human oral cavity and is the causative agent for localized aggressive periodontitis (LAP), an aggressive form of periodontal disease that occurs in adolescents. A. actinomycetemcomitans secretes a protein toxin, leukotoxin (LtxA), which helps the bacterium evade the ...
openaire   +2 more sources

Are leukotoxins toxic? [PDF]

open access: yesNature Medicine, 1997
Takeshi Ishizaki   +2 more
openaire   +2 more sources

Severe Necrotizing Community‐Acquired Pneumonia and Bilateral Empyema in an Immunocompetent Patient due to Fusobacterium necrophorum

open access: yesCase Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Necrotizing pneumonia and empyema caused by Fusobacterium necrophorum are uncommon. The classical presentation of Lemierre′s syndrome, characterized by pharyngotonsillitis and internal jugular vein thrombosis, is not always observed, and incomplete and atypical variants can cause diagnostic uncertainty and delay in treatment.
Deborah Shefa   +7 more
wiley   +1 more source

Genome Analysis of Staphylococcus aureus Isolated From the Feces of Diarrheal Patients in the Region of East China, 2019–2024

open access: yesInternational Journal of Food Science, Volume 2026, Issue 1, 2026.
Staphylococcus aureus is a leading cause of foodborne diarrhea, primarily due to staphylococcal enterotoxins (SEs). This study employed whole‐genome sequencing to characterize 106 S. aureus isolates from diarrheal patients in East China (2019–2024). We identified 23 sequence types, with ST398 (22.6%) and ST5 (7.5%) among the most prevalent.
Jinzhi Zhang   +7 more
wiley   +1 more source

Concordance in diagnostic testing for respiratory pathogens of bighorn sheep

open access: yesWildlife Society Bulletin, 2016
Reliable diagnostic tests are essential for disease investigation and management. This is particularly true for diseases of free‐ranging wildlife where sampling is logistically difficult precluding retesting.
Daniel P. Walsh   +12 more
doaj   +1 more source

Role of carriers in the transmission of pneumonia in bighorn sheep (Ovis canadensis)

open access: yesBiology Open, 2016
In the absence of livestock contact, recurring lamb mortality in bighorn sheep (Ovis canadensis) populations previously exposed to pneumonia indicates the likely presence of carriers of pneumonia-causing pathogens, and possibly inadequate maternally ...
Bindu Raghavan   +7 more
doaj   +1 more source

Periodontal Ecosystem and Clinical Implications of the Oral Microbiome: A Narrative Review

open access: yesInternational Journal of Dentistry, Volume 2026, Issue 1, 2026.
Background Periodontal disease, although widely documented, remains one of the leading causes of tooth loss worldwide. This situation can be attributed to patients’ difficulty in following treatment protocols and to an incomplete understanding of the disease’s mechanisms, which could be explored to develop new therapies.
Ana Júlia Martins Targino   +5 more
wiley   +1 more source

Effects of Aggregatibacter actinomycetemcomitans leukotoxin on neutrophil migration and extracellular trap formation

open access: yesJournal of Oral Microbiology, 2016
Background: Aggressive periodontitis is associated with the presence of Aggregatibacter actinomycetemcomitans, a leukotoxin (Ltx)-producing periodontal pathogen. Ltx has the ability to lyse white blood cells including neutrophils.
Josefine Hirschfeld   +6 more
doaj   +1 more source

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides

open access: yesJournal of Lipid Research, 2004
CYP4F isoforms are involved in the oxidation of important cellular mediators such as leukotriene B4 (LTB4) and prostaglandins. The proinflammatory agent LTB4 and cytotoxic leukotoxins have been associated with several inflammatory diseases.
Valérie Le Quéré   +4 more
doaj   +1 more source

Heterogeneity of Size and Toxin Distribution in Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles

open access: yesToxins
Aggregatibacter actinomycetemcomitans is a Gram-negative bacterium associated with localized aggressive periodontitis as well as some systemic diseases. The strains of A.
Justin B Nice   +6 more
doaj   +1 more source

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