Regulatory roles of bioactive lipids in vascular homeostasis and remodeling. [PDF]
Yang J +4 more
europepmc +1 more source
Environmentally relevant enrofloxacin accelerates intestinal aging by impairing epithelial mitochondrial function, disrupting barrier integrity, and reshaping the gut microbiota. Mitochondrial restoration with pyrroloquinoline quinone alleviates hypoxia, inflammation, and gut damage.
Kan Yu +10 more
wiley +1 more source
Modulation of Neutrophil Recruitment and Inflammatory Signaling in Acute Respiratory Distress Syndrome by Leukotriene Inhibitors Montelukast and Zileuton. [PDF]
Biedritzky A +8 more
europepmc +1 more source
Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Structure-based identification of compounds with potential as selective BLT1 antagonists. [PDF]
Alkhodier RA +3 more
europepmc +1 more source
ABSTRACT Allergic rhinitis (AR) is a prevalent chronic condition that significantly impacts patients' quality of life and poses challenges to effective management. Traditional Chinese medicine (TCM) offers a holistic approach, emphasizing syndrome differentiation, individualized care, and natural treatment strategies.
Qin‐Wei Fu +74 more
wiley +1 more source
Nemolizumab as an Alternative Therapeutic Option for Indolent Systemic Mastocytosis. [PDF]
Minbaeva S, Tyring SK.
europepmc +1 more source
Anti-inflammatory activity of beta-sitosterol in a model of oxazolone-induced contact delayed type hypersensitivity. [PDF]
Giner, RM, Prieto-Garcia, JM, Recio, MC
core
Chinese Position Paper on Biologic Therapy for Allergic Rhinitis
ABSTRACT Allergic rhinitis (AR) is a common, persistent nasal disorder that poses significant public health challenges worldwide. Current treatment options frequently fail to achieve adequate symptom control in a substantial subset of patients. Over the past two decades, biologic therapies that target type 2 inflammatory pathways have been used to ...
Yuan Zhang +37 more
wiley +1 more source
CysLT<sub>1</sub> Receptor Activation Decreases Na<sup>+</sup>/K<sup>+</sup>-ATPase Activity via PKC-Mediated Mechanisms in Hippocampal Slices. [PDF]
Rambo LM +6 more
europepmc +1 more source

