Leukotrienes - Open Access .click

Results 121 to 130 of about 68,425 (301)

Allergy, EarlyView.
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source

Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part II—Guidelines on Oral and Ocular Treatments

Allergy, EarlyView.
ABSTRACT Background Oral and ocular medications are frequently used in the treatment of allergic rhinitis (AR). As part of the update of the Allergic Rhinitis and its Impact on Asthma (ARIA)‐EAACI guidelines, this manuscript presents the ARIA‐EAACI 2024–2025 recommendations for oral and ocular treatments.
Rafael José Vieira +230 more
wiley +1 more source

Simulation adsorption characteristics of fullerene dispersions

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов
Mechanisms of action of fullerenes on biological systems are not yet fully understood. Fullerenes can be modified to increase their efficiency and safety in medicine and drug delivery. Various ligands can be attached to them increasing their selectivity
O.A. Dyudyun +3 more
doaj +1 more source

Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock [PDF]

, 2022
Marta Reina‐Couto +14 more
openalex +1 more source

Chinese Position Paper on Biologic Therapy for Allergic Rhinitis

Allergy, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a common, persistent nasal disorder that poses significant public health challenges worldwide. Current treatment options frequently fail to achieve adequate symptom control in a substantial subset of patients. Over the past two decades, biologic therapies that target type 2 inflammatory pathways have been used to ...
Yuan Zhang +37 more
wiley +1 more source

A current review on animal models of anti-asthmatic drugs screening

Frontiers in Pharmacology
Asthma is a chronic inflammatory respiratory condition characterised by airway constriction, smooth muscle spasm, and severe morbidity. It affects around 300 million people globally, with children being especially vulnerable. Despite its worldwide effect,
Shivam Singh +5 more
doaj +1 more source

Acute coronary syndrome in diclofenac sodium-induced type I hypersensitivity reaction : Kounis syndrome [PDF]

, 2007
Drug-induced type I hypersensitivity reactions are frequent. Sometimes, acute coronary syndrome (ACS) can be registered in such patients, which may have a serious impact on the course and management of the allergic reaction.
Gluvic, Zoran M. +5 more
core

TBXA2R gene polymorphism and responsiveness to leukotriene receptor antagonist in children with asthma [PDF]

, 2008
Jae‐Hoon Kim +9 more
openalex +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

Allergy, EarlyView.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama +16 more
wiley +1 more source

Leukotriene B4 stimulation of phagocytes results in the formation of inositol 1,4,5-trisphosphate A second messenger for Ca2+ mobilization [PDF]

, 1986
Tommy Andersson +5 more
openalex +1 more source

asthma
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leukotriene

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