Results 161 to 170 of about 28,774 (254)

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source

Leukotriene B4 regulates T cell recognition and control of MCMV in mucosal tissues. [PDF]

Mucosal Immunol
Springer LE, Rao HZ, Abinader O, Mitra R, Snyder CM.   +4 more
europepmc   +1 more source

Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Zixu Wang, Xin Fu, Jingchao Bai, Yanguo Liu, Kai Huang   +4 more
wiley   +1 more source

Mast cell metabolism in cancer: an underexplored frontier demanding more attention. [PDF]

Front Immunol
Frossi B, Scialpi GB, Tonon S, Jachetti E.   +3 more
europepmc   +1 more source

Lymphatic Endothelial Cells in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang, Wang Lin, Hengyang Liu, Jixin Zhong, Shiliang Li, Xiaoquan Rao   +5 more
wiley   +1 more source

Editorial: Exploring the interconnection: obesity's role in asthma development and management. [PDF]

Front Allergy
Yamasaki A, Tomita K.
europepmc   +1 more source

Straightforward Synthesis, Spectroscopic Characterizations, Molecular Docking, Molecular Dynamics Simulations, and Comprehensive DFT Calculations of Novel Tetrazole 1,5 and 2,5‐Disubstituted Tetrazole Scaffolds

ChemistryOpen, Volume 15, Issue 8, August 2026.
A series of novel 1,5‐ and 2,5‐disubstituted tetrazole heterocyclic scaffolds was synthesized and characterized by single‐crystal X‐ray diffraction. Their electronic properties were investigated using density functional theory calculations, while molecular docking and molecular dynamics simulations revealed promising biological potential and favorable ...
Riham Sghyar, Ahmed Chelouan, Brahim El Ibrahimi, Olivier Blacque, Basavarajaiah Suliphuldevara Mathada, Prashantha Karunakar, Oussama Moussaoui, Mouad Lahyaoui, Joel T. Mague, Ali Aghmiz, Manal El‐Gendy, Mohamed Hefnawy, Nada Kheira Sebbar   +12 more
wiley   +1 more source

Fish Oil-Containing Injectable Lipid Emulsions in Parenteral Nutrition: Immunomodulation and Clinical Outcomes in Critically Ill Patients-Narrative Review. [PDF]

Nutrients
Kęska M, Kęska M, Perliński M, Pabich P, Onichimowski D.   +4 more
europepmc   +1 more source

Dissociated Biologic Responses Across the United Airway: A Case Report of Severe Asthma With Chronic Rhinosinusitis With Nasal Polyps and Eosinophilic Otitis Media

Respirology Case Reports, Volume 14, Issue 8, August 2026.
We report a case of severe asthma with chronic rhinosinusitis with nasal polyps and eosinophilic otitis media that was successfully controlled by switching biologic therapy from dupilumab to mepolizumab. Careful monitoring of disease activity and consideration of biologic switching may help achieve optimal control with currently available biologics ...
Tomoko Tajiri, Naoki Takemoto, Toshiya Minakata, Motohiko Suzuki, Yoshiyuki Ozawa, Hirotsugu Ohkubo   +5 more
wiley   +1 more source

DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis. [PDF]

Nat Commun
Luo W, Xu W, Yin Q, Song J, Wang J, Guan Y, Huang J, Yu J, Zou K, Jin D, Xu C, Qiu M, Qiu Z, Zhong J.   +13 more
europepmc   +1 more source