Results 51 to 60 of about 2,023,090 (375)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Family planning (FP) utilization impacts individuals, families, communities and nations. The study aimed at comparing family planning predictors, male involvement in family planning and unmet fertility needs in rural and urban areas of Lagos, Nigeria. A
Ifeoma P. Okafor +3 more
doaj
Pengaruh Manajemen Keluarga Terhadap Penghindran Pajak
Abstrak Pajak merupakan pendapatan terbesar negara akan tetapi realisasi penerimaan pajak negara selalu tidak sesuai dengan target penerimaan yang dibuat pemerintah.
Rachma Kartika Putri
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This research aims to examine whether there is any influence of investment opportunity set (IOS) on the affiliation between dividend policy and free cash flow to leverage enterprise-level.
Masruroh Masruroh +2 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Struktur modal: Faktor penentu dan pengaruhnya pada nilai perusahaan
Penelitian ini mempunyai dua tujuan utama yakni, pertama untuk mengetahui dan menganalisis faktor-faktor yang menentukan struktur modal, kedua untuk mengetahui dan menganalisis pengaruh faktor-faktor penentu struktur modal terhadap nilai perusahaan ...
Sutrisno Sutrisno
doaj
Penelitian ini bertujuan untuk menguji pengaruh Ukuran Perusahaan, Umur Perusahaan, Leverage, dan Profitabilitas terhadap Manajemen Laba pada Perusahaan Pertambangan yang terdaftar di Bursa Efek Indonesia tahun 2014-2016.
Yofi Prima Agustia, Elly Suryani
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

