Results 41 to 50 of about 39,898 (187)

Botulinum toxin type A for Holmes tremor secondary to thalamic hemorrhage [PDF]

, 2015
Holmes tremor (HT) is a low-frequency rest and intentional tremor frequently affecting the upper limb.
Giovannelli, Morena, Latino, Pamela, Orzi, Francesco, Pontieri, FRANCESCO ERNESTO   +3 more
core   +1 more source

Levetiracetam reverses synaptic deficits produced by overexpression of SV2A. [PDF]

PLoS ONE, 2011
Levetiracetam is an FDA-approved drug used to treat epilepsy and other disorders of the nervous system. Although it is known that levetiracetam binds the synaptic vesicle protein SV2A, how drug binding affects synaptic functioning remains unknown.
Amy Nowack, Erik B Malarkey, Jia Yao, Adam Bleckert, Jessica Hill, Sandra M Bajjalieh   +5 more
doaj   +1 more source

Treatment for the Benign Childhood Epilepsy With Centrotemporal Spikes: A Monocentric Study

Frontiers in Neurology, 2021
Background and Purpose: To date, there is no specific treatment guideline for the benign childhood epilepsy with centrotemporal spikes (BECTS). Several countries recommend levetiracetam, carbamazepine, sodium valproate, oxcarbazepine, and lamotrigine as ...
Miriam Kessi, Miriam Kessi, Fangling Yan, Fangling Yan, Langui Pan, Langui Pan, Baiyu Chen, Baiyu Chen, Eleonore Olatoutou, Eleonore Olatoutou, Dong Li, Dong Li, Fang He, Fang He, Tibera Rugambwa, Lifen Yang, Lifen Yang, Jing Peng, Jing Peng, Fei Yin, Fei Yin   +20 more
doaj   +1 more source

Prognostic value of early magnetic resonance imaging in dogs after traumatic brain injury: 50 cases [PDF]

, 2014
Retrospective study of dogs with TBI that underwent 1.5T MRI within 14 days after head trauma. MRI evaluators were blinded to the clinical presentation, and all images were scored based on an MRI grading system (Grade I [normal brain parenchyma] to Grade
Asikainen, Bazarian, Bigler, Brain Trauma Foundation, Byrne, Chew, Englander, Firsching, Frey, Friedenberg, Hicks, Hilario, Kearsley-Fleet, Klein, Kornegay, Lagares, Lannsjö, Lee, Lowenstein, Löscher, Management of Concussion/mTBI Working Group, McDonald, Mittl, Orrison, Pearl, Platt, Sande, Schwartz-Porsche, Shenton, Shores, Simpson, Skandsen, Steinmetz, Tanoue, Vespa, Wendt-Hornickle, Wilde, Yuh, Zuercher   +38 more
core   +2 more sources

Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1 [PDF]

, 2017
The clinical and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback dogs (6 wk to 18 mo) are described.
Arumilli, Meharji, Bathen-Noethen, Andrea, Bhatti, Sofie, Boettcher, Irene C, Cortez, Miguel A, Dietschi, Elisabeth, Fischer, Andrea, Flegel, Thomas, Hytönen, Marjo K, Hülsmeyer, Velia, James, Fiona, Kluger, Gerhard, Kornberg, Marion, Koskinen, Lotta LE, Leeb, Tosso, Lohi, Hannes, Matiasek, Kaspar, Rentmeister, Kai, Sarviaho, Riika, Tipold, Andrea, Tästensen, Carina, Wielaender, Franziska   +21 more
core   +1 more source

The efficacy of direct oral anticoagulants in patients on concomitant treatment with levetiracetam

Scientific Reports, 2023
Guidelines do not support the combination of direct oral anticoagulants (DOACs) and the antiepileptic drug levetiracetam, due to potential relevant P-glycoprotein (P-gp) mediated interaction that might result in decreased DOACs concentrations and ...
Alenka Mavri, Sara Ilc
doaj   +1 more source

Levetiracetam attenuates diabetes-associated cognitive impairment and microglia polarization by suppressing neuroinflammation

Frontiers in Pharmacology, 2023
Introduction: Cognitive impairment is a common complication and comorbidity of diabetes. However, the underlying mechanisms of diabetes-associated cognitive dysfunction are currently unclear.
Yun-yun Zhang, Yun-yun Zhang, Lu Wang, Lu Wang, Hua Guo, Hua Guo, Ting-ting Han, Ting-ting Han, Yan-hua Chang, Yan-hua Chang, Xiao-chuan Cui, Xiao-chuan Cui   +11 more
doaj   +1 more source

Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy [PDF]

, 2018
Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease.
A Klang, A Pakozdy, A Pakozdy, A Pakozdy, A Pellegrini, AD Quesnel, Akos Pakozdy, AM Wahle, AS Sawchuk, C Bertolani, CR Hooijmans, CW Dewey, D Hasegawa, D Hughes, D Moher, D Schwartz-Porsche, D Schwartz-Porsche, DB Roye, DE Cuff, DL Zoran, DM Boothe, DM Brewer, G Zaccara, G Zaccara, GE Solomon, GH Guyatt, H Volk, Holger A. Volk, JA Berlin, JA Wada, JAD Gasper, JM Ducote, KE Finnerty, KS Bailey, KS Bailey, LR Barnard, M Charalambous, M Charalambous, M Lowrie, M Podell, MA Cautela, MA Holmes, Marios Charalambous, MB Carnes, MJ Baho, NM van Gelder, O Engel, P Boydell, PN Papanikolaou, R Chou, S Cizinauskas, S Schriefl, S Wagner, SA Center, SD Ross, SF Bhatti, SM Cochrane, SM Cochrane, Sofie F. M. Bhatti   +58 more
core   +3 more sources

Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy. [PDF]

, 2019
Aminoacyl-tRNA synthetases (ARSs) function to transfer amino acids to cognate tRNA molecules, which are required for protein translation. To date, biallelic mutations in 31 ARS genes are known to cause recessive, early-onset severe multi-organ diseases ...
Accogli, Andrea, Ben-Omran, Tawfeg, Bernard, Geneviève, Chowdhury, Shimul, Crawford, John R, Dimmock, David, Friedman, Jennifer, Gleeson, Joseph G, Guerrero, Kether, Hildreth, Amber, Issa, Mahmoud Y, James, Kiely N, Kingsmore, Stephen F, Koehler, Alanna E, Lo, Wing-Sze, Mendes, Marisa I, Musaev, Damir, Nahas, Shareef, Omar, Tarek EI, Salomons, Gajja S, Smith, Desiree E, Stanley, Valentina, Tran, Luan T, Wang, Rengang, Wigby, Kristen, Wright, Meredith S, Xu, Zhiwen, Zaki, Maha S, Zhai, Liting   +28 more
core   +2 more sources

Comparison of levetiracetam as second-line drug with fosphenytoin in convulsive status epilepticus among children: A single center, open-label randomized controlled trial

Journal of Pediatric Critical Care, 2023
Background: Status epilepticus (SE) is the most common neurologic emergency in the pediatric age group often serious and life-threatening. Although newer drugs were used, morbidity and mortality are still high. This study was done to compare the efficacy
S Anupama, V Poovazhagi, R Nisha, S Suresh Kumar, J Sathya   +4 more
doaj   +1 more source