Results 51 to 60 of about 3,343,278 (165)
Levodopa-induced dyskinesia is strongly associated with resonant cortical oscillations. [PDF]
, 2012 The standard pharmacological treatment for Parkinson's disease using the dopamine precursor levodopa is unfortunately limited by gradual development of disabling involuntary movements for which the underlying causes are poorly understood.
Halje, Pär +5 more
core +1 more source
Advanced Science, EarlyView.Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu +12 more
wiley +1 more source
Effect of Subthalamic Deep Brain Stimulation on Levodopa-Induced Dyskinesia in Parkinson's Disease [PDF]
, 2015 PURPOSE: To evaluate the effect of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) on levodopa-induced peak-dose dyskinesia in patients with Parkinson's disease (PD).
정현호 +3 more
core +1 more source
Neurobiology of Disease, 2009 It has been suggested, based on rodent studies, that levodopa (l-dopa) induced dyskinesia is associated with a disrupted blood–brain barrier (BBB). We have investigated BBB integrity with in vivo neuroimaging techniques in six 1-methyl-4-phenyl-1,2,3,6 ...
Arnar Astradsson +8 more
doaj +1 more source
NMDAR‐antibody encephalitis: Seizure semiology and EEG findings
Epileptic Disorders, EarlyView.Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus +6 more
wiley +1 more source
Nature Communications, 2022 Here, the authors studied how cerebellar stimulation alleviates levodopa-induced dyskinesia (LID). They demonstrated that Purkinje cell opto-stimulation is sufficient to prevent LID development and can normalize brain activity in a wide motor network in ...
Bérénice Coutant +11 more
doaj +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Investigação do potencial antidiscinético da agmatina em camundongos: envolvimento do estresse oxidativo, óxido nítrico e receptores glutamatérgicos no tipo NMDA [PDF]
, 2015 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2015.As discinesias representam por uma série de movimentos involuntários orofaciais, do tronco e ...
Cunha, Andréia Simões de Castro
core
Aberrant Striatal Activity in Parkinsonism and Levodopa-Induced Dyskinesia [PDF]
, 2018 Action selection relies on the coordinated activity of striatal direct and indirect pathway medium spiny neurons (dMSNs and iMSNs, respectively). Loss of dopamine in Parkinson's disease is thought to disrupt this balance.
Chloe Bair-Marshall +5 more
core +1 more source
Neurology Perspectives, 2021 Resumen: La enfermedad de Parkinson (EP) es una enfermedad neurodegenerativa cuyo tratamiento sintomático más eficaz es la L-dopa, sin embargo, puede inducir discinesias (DIL).
J.C. Guzman +5 more
doaj +1 more source