Results 51 to 60 of about 60,411 (353)
Parkinson's Disease, 2022 Background. Rasagiline is a selective, irreversible monoamine oxidase type B inhibitor used as monotherapy in early Parkinson’s disease and as an adjunct therapy to levodopa in Parkinson’s disease with motor fluctuations. Objectives.
Osamu Kano +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong +7 more
wiley +1 more source
Long‐term safety and efficacy of levodopa‐carbidopa intestinal gel in advanced Parkinson's disease
Movement Disorders, 2018 Background: Levodopa‐carbidopa intestinal gel (designated as carbidopa‐levodopa enteral suspension in the United States) provides stable plasma levodopa concentrations and reduces motor fluctuations in advanced Parkinson's disease patients through ...
H. Fernandez +15 more
semanticscholar +1 more source
Progress in Flexible Perovskite Solar Cells: Paving the Way for Scalable Manufacturing
Advanced Materials Technologies, EarlyView.Perovskite solar cells (PSCs) are well positioned for a successful market uptake. This is due to an unprecedented improvement of their efficiency and stability since the first report in 2009. In this review paper, the building blocks for the scalable manufacturing and future commercialization of flexible PSCs and their pathway to impact will be ...
Dimitar I. Kutsarov +5 more
wiley +1 more source
Levodopa-induced dyskinesia in Parkinson disease
Neurology, 2018 Objective To assess dyskinesia frequency in a population-based cohort of patients with Parkinson disease (PD). Dyskinesia complicates levodopa treatment and affects quality of life.
Pierpaolo Turcano +6 more
semanticscholar +1 more source
Microneedles at the Forefront of Next Generation Theranostics
Advanced Science, EarlyView.The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang +8 more
wiley +1 more source
Movement Disorders, 2017 The treatment of levodopa‐induced dyskinesia in Parkinson's disease (PD) is an unmet need with no approved drug therapy.
W. Oertel +10 more
semanticscholar +1 more source
Advanced Science, EarlyView.Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li +12 more
wiley +1 more source
Extended-release oral capsule of carbidopa–levodopa in Parkinson disease
Therapeutic Advances in Neurological Disorders, 2018 Motor fluctuations complicate the treatment of patients with Parkinson’s disease receiving levodopa. Extended-release carbidopa–levodopa has a pharmacokinetic profile that provides a more continuous levodopa serum concentration.
Jason Margolesky, Carlos Singer
doaj +1 more source
Effect of Rectal Levodopa Administration: A Case Report
Case Reports in Neurology, 2015 Objective: The aim of this report is to discuss whether or not rectal levodopa administration is useful in some situations. Background: In situations where oral intake of levodopa formulations is not possible, the treatment options of Parkinson's disease
Jolanda M.J. Vogelzang +2 more
doaj +1 more source