Results 41 to 50 of about 53,685 (285)

Levodopa versus non-levodopa brain language fMRI in Parkinson's disease

Einstein (São Paulo)
OBJECTIVE: To identify the effect of levodopa in language areas in Parkinson's disease patients. METHODS: We evaluated 50 patients with mild to moderate Parkinson's disease, age and gender paired to 47 healthy volunteers.
Paula Ricci Arantes, Heloise Helena Gobato, Bárbara Bordegatto Davoglio, Maria Ângela Maramaldo Barreiros, André Carvalho Felício, Orlando Graziani Povoas Barsottini, Luiz Augusto Franco de Andrade, Edson Amaro Junior   +7 more
doaj   +1 more source

Wearable Evidence Linking Dyskinesia Burden to Sleep Quality in Parkinson's Disease. [PDF]

Mov Disord Clin Pract
Abstract Background Sleep disturbances affect 60–80% of people with Parkinson's disease (PD) and worsen quality of life. Dyskinesia is a common complication of dopaminergic therapy, yet its link to sleep quality is poorly understood. Objectives To examine whether clinician‐rated and objectively measured dyskinesia are associated with sleep quality in ...
Azoidou V, Bhadra E, Camboe E, Dey KC, Zirra A, Rowsell K, Quah C, Budu C, Boyle T, Gallagher D, Bestwick JP, Pérez-Carbonell L, Noyce AJ, Simonet C.   +13 more
europepmc   +2 more sources

Dopa-responsive dystonia and hyperprolactinaemia : a novel association in two sisters [PDF]

, 2007
Dopa-Responsive Dystonia (DRD) is a rare hereditary condition of childhood-onset dystonia which responds dramatically to treatment with levodopa. It was first described in 1971 as a "hereditary progressive basal ganglia disease with marked diurnal ...
Cachia, Mario J., Galea, Janabel
core  

Pharmacokinetics of levodopa/carbidopa microtablets versus levodopa/benserazide and levodopa/carbidopa in healthy volunteers

, 2012
OBJECTIVES: To compare bioavailability and pharmacokinetics of single doses of 3 different levodopa formulations given orally in healthy volunteers. Two marketed formulations, standard levodopa/carbidopa, 100/25 mg (LC-100), and dispersible levodopa ...
Nyström, Christer, Bäckström, Tobias, Gomes-Trolin, Cecilia, Nystrom, C, Nyholm, D, Gomes-Trolin, C, Lewander, T, Nyholm, Dag,, Aquilonius, Sten-Magnus,, Panagiotidis, Georgios, Lewander, Tommy,, Ehrnebo, M, Aquilonius, S-M, Panagiotidis, G, Backstrom, T, Ehrnebo, Mats   +15 more
core   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Optimizing levodopa therapy to treat wearing-off symptoms in Parkinson's disease: focus on levodopa/carbidopa/entacapone

, 2012
Levodopa has been the mainstay of Parkinson's disease (PD) therapy for over 40 years, with its efficacy surpassing that of other antiparkinsonian medications.
Emre, Murat, Reichmann, Heinz
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Levodopa versus non-levodopa brain language fMRI in Parkinson’s disease [PDF]

Einstein (São Paulo), 2012
Objective: To identify the effect of levodopa in language areas inParkinson’s disease patients. Methods: We evaluated 50 patientswith mild to moderate Parkinson’s disease, age and gender pairedto 47 healthy volunteers.
Paula Ricci Arantes, Heloise Helena Gobato, Bárbara Bordegatto Davoglio, Maria Ângela Maramaldo Barreiros, André Carvalho Felício, Orlando Graziani Povoas Barsottini, Luiz Augusto Franco de Andrade, Edson Amaro Junior   +7 more
doaj  

Levodopa-Responsive Parkinsonism Preceded by Isolated Upper Limb Tremor Associated with PTEN Variant. [PDF]

Mov Disord Clin Pract
Movement Disorders Clinical Practice, EarlyView.
Gandhi SE, Siripurapu R, Smith A, Kobylecki C.   +3 more
europepmc   +2 more sources

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

Advanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park, Ki‐Yoon Park, Yeonho Choi, Dong‐Myeong Shin, Hong‐Joon Yoon, Hocheon Yoo   +5 more
wiley   +1 more source