Results 71 to 80 of about 15,116 (246)
Orthostatic stability with intravenous levodopa [PDF]
, 2015 Intravenous levodopa has been used in a multitude of research studies due to its more predictable pharmacokinetics compared to the oral form, which is used frequently as a treatment for Parkinson’s disease (PD).
Siddiqi, Shan H +5 more
core +2 more sources
Interdisciplinary Medicine, EarlyView.This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang +13 more
wiley +1 more source
, 2012 Levodopa has been the mainstay of Parkinson's disease (PD) therapy for over 40 years, with its efficacy surpassing that of other antiparkinsonian medications.
Emre, Murat, Reichmann, Heinz
core +1 more source
The effects of royal jelly on human health: A narrative review of clinical studies
JSFA reports, EarlyView.Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras +2 more
wiley +1 more source
Extended-release oral capsule of carbidopa–levodopa in Parkinson disease
Therapeutic Advances in Neurological Disorders, 2018 Motor fluctuations complicate the treatment of patients with Parkinson’s disease receiving levodopa. Extended-release carbidopa–levodopa has a pharmacokinetic profile that provides a more continuous levodopa serum concentration.
Jason Margolesky, Carlos Singer
doaj +1 more source
Inhalable levodopa: from laboratory to the patient [PDF]
, 2020 Levodopa is effective in alleviating the motor symptoms of Parkinson’s disease, but a high variability in levodopa absorption from the gastrointestinal tract after oral administration causes fluctuations in the levodopa plasma concentration.
Luinstra, Marianne
core +13 more sources
Frontiers in Neurology, 2019 Although the administration of dopamine precursor levodopa remains as the mainstay for the treatment of Parkinson's disease, long-term exposure to levodopa often causes a disabling complication, referred to as levodopa-induced dyskinesias. Therefore, the
Masatoshi Ogawa +9 more
doaj +1 more source
Considerações terapêuticas na doença de Parkison de longa evolução. [PDF]
, 1988 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Chikota, Ediles Miers
core
Effect of Rectal Levodopa Administration: A Case Report
Case Reports in Neurology, 2015 Objective: The aim of this report is to discuss whether or not rectal levodopa administration is useful in some situations. Background: In situations where oral intake of levodopa formulations is not possible, the treatment options of Parkinson's disease
Jolanda M.J. Vogelzang +2 more
doaj +1 more source
Levodopa-responsive depression associated with corticobasal degeneration: a case report [PDF]
, 2017 Natsumi Tarakita,1 Haruo Nishijima,2 Norio Yasui-Furukori1 1Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, 2Department of Neurology, Aomori Prefectural Central Hospital, Aomori, Japan Abstract: A 60-year-old ...
Nishijima, Haruo +8 more
core +1 more source