Results 91 to 100 of about 12,501 (219)

Controlling Levonorgestrel Binding and Release in a Multi-Purpose Prevention Technology Vaginal Ring Device

open access: yes, 2016
Despite a long history of incorporating steroids into silicone elastomers for drug delivery applications, little is presently known about the propensity for irreversible drug binding in these systems.
Boyd, Peter   +7 more
core   +1 more source

Bioequivalence of a Fixed‐Dose Combination of Relugolix, Estradiol, and Norethindrone Acetate: An Open‐Label, Randomized, Fully Replicate Crossover Study in Healthy Postmenopausal Women Under Fasting Conditions

open access: yesClinical Pharmacology in Drug Development, Volume 15, Issue 6, June 2026.
Abstract Uterine fibroids are the most common benign gynecological tumors, often causing heavy menstrual bleeding (HMB), anemia, and impaired quality of life. A fixed‐dose combination (FDC) of relugolix (40 mg), estradiol (1 mg), and norethindrone acetate (0.5 mg) was developed to address these limitations.
Ravi Kotadia   +6 more
wiley   +1 more source

The levonorgestrel-releasing intrauterine system: Safety, efficacy, and patient acceptability

open access: yes, 2009
Megan N Beatty, Paul D BlumenthalDepartment of Obstetrics and Gynecology, Stanford University, Stanford, CA, USAAbstract: The levonorgestrel-releasing intrauterine system (LNG-IUS) is a safe, effective and acceptable form of contraception used by over ...
Megan N Beatty, Paul D Blumenthal
core  

Women with epilepsy: Evidence‐based counseling across the lifespan

open access: yesEpilepsia, Volume 67, Issue 6, Page 2689-2706, June 2026.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn   +7 more
wiley   +1 more source

A randomized clinical trial to compare levonorgestrel-releasing intrauterine system (Mirena) vs trans-cervical endometrial resection for treatment of menorrhagia

open access: yes, 2011
Shirin Ghazizadeh1, Fatemeh Bakhtiari1, Haleh Rahmanpour2, Fatemeh Davari-Tanha1, Fatemeh Ramezanzadeh11Valie-Asr Reproductive Health Research Center, Valie-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran; 2Department of Obstetrics and ...
Davari-Tanha F   +4 more
core  

Determination of ethinyl estradiol and levonorgestrel in human plasma with prednisone as internal standard using ultra-performance liquid chromatography–tandem mass spectrometry

open access: yesJournal of Pharmacy and Bioallied Sciences, 2019
Objective: Ethinyl estradiol and levonorgestrel as a combination of oral contraceptive drugs have very low dosage levels; hence, a highly sensitive and selective method of using ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS)
Yahdiana Harahap   +2 more
doaj   +1 more source

A Novel Semi‐Quantified Method for Grading Sonographic Severity of Adenomyosis and its Relation With Clinical Symptoms

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 6, Page 1259-1274, June 2026.
Objective To correlate the sonographic severity of adenomyosis, assessed with real‐time ultrasound and a novel semi‐quantified method (XI‐VOCAL counting and categories) with adenomyosis‐associated symptoms. Methods This observational study was conducted in a tertiary referral outpatient clinic.
Lisa M. Trommelen   +5 more
wiley   +1 more source

The levonorgestrel intrauterine system: Long-term contraception and therapeutic effects

open access: yes, 2005
The levonorgestrel intrauterine system (Mirena®) has been developed as a long-acting method of contraception. This medicated device, inserted into the uterus, delivers a small daily dose of a progestin, levonorgestrel, into the uterine cavity.
Inki, Pirjo, Sitruk-Ware, Régine
core   +1 more source

Assessment of Incessant Intake of Levonorgestrel Oral Contraceptive and the Effect of Drug Withdrawal on Liver Function and Integrity

open access: yesJournal of Health Science and Medical Research (JHSMR)
Objective: This study used female Wistar rats to evaluate the impact of incessant intake of levonorgestrel on liver function and integrity, and to observe the effect of drug withdrawal on the organs. (organ).
Catherine Adeniji   +4 more
doaj   +1 more source

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