Results 21 to 30 of about 13,710 (215)

A Physiologically-Based Pharmacokinetic Simulation to Evaluate Approaches to Mitigate Efavirenz-Induced Decrease in Levonorgestrel Exposure with a Contraceptive Implant

Pharmaceutics
Background: Levonorgestrel implant is a highly effective hormonal contraceptive, but its efficacy may be compromised when used with cytochrome enzyme inducers such as efavirenz. The primary aim of this study was to evaluate methods of mitigating the drug
Lilian W. Adeojo, Rena C. Patel, Nancy C. Sambol   +2 more
doaj   +1 more source

Do Norwegian providers comply with national recommendations when prescribing combined oral contraceptives to starters? A cohort study

BMJ Open, 2019
Objectives To assess whether changes in patterns of combined oral contraceptive (COC) prescriptions to starters between 2008 and 2016 were in line with changes in national recommendations for use.Design Historical prospective cohort study.Setting The ...
Julie Ekman, Finn Egil Skjeldestad
doaj   +1 more source

Two Cases of Acute Cholecystitis and Symptomatic Choledocholithiasis in Two Women Less than 40-Years-of-Age with Hormonal Intrauterine Devices

Case Reports in Gastrointestinal Medicine, 2018
Levonorgestrel uterine implants are accepted as a safe and efficacious method of contraception. One of the two major health side effects in a large controlled study of subcutaneous hormonal implants with levonorgestrel was a significant increase in ...
Helen M. Shields, Hasrat Sidhu
doaj   +1 more source

COMPARATIVE ANALYSIS OF REQUIREMENTS FOR QUALITY CONTROL OF ETHINYL ESTRADIOL AND LEVONORGESTREL CONTAINING MEDICINAL PRODUCTS

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article compares test methods and levels of requirements laid out in the world’s leading pharmacopoeias and in manufacturers’ specifications with regard to the quality of levonorgestrel and ethinyl estradiol containing medicinal products used as oral
V. I. Seredenko, A. V. Korolev, L. G. Maslov, T. Yu. Belova, N. N. Dolgushina   +4 more
doaj   +1 more source

Levonorgestrel-Intrauterine Device for Chronic Pelvic Pain: Decreasing Menstrual Frequency, But Not Surgical Intervention Prior to Insertion, Predicts Improved Pain Scores

, 2021
Levonorgestrel-Intrauterine Device for Chronic Pelvic Pain: Decreasing Menstrual Frequency, But Not Surgical Intervention Prior to Insertion, Predicts Improved Pain ...
I Conroy (13449150), A Fitzgerald (9865709), I Jakab (13448868), S Mooney (13449153), S Grover (9883580), J Porter (7939469), N Origanti (13448883), M Sewell (13448892), S Maxwell (13448877), M Duff (13448865), A McCutchan (13449162), S Madden (7755818), Shane Kavanagh (13094145), K Robertson (13324230), K Mirowska--Allen (13449165), A Quinless (13449156), S Nair (13448880)   +16 more
core  

The Cost-Effectiveness of Emergency Hormonal Contraception with Ulipristal Acetate versus Levonorgestrel for Minors in France.

PLoS ONE, 2015
ObjectiveTo evaluate the cost-effectiveness of ulipristal acetate and levonorgestrel in minors in France, and analyze whether it is worthwhile to provide ulipristal acetate to minors free of charge.MethodsThe cost-effectiveness of two emergency ...
Ramona Schmid
doaj   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen, Amnah Omar Mahajna, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

The Levonorgestrel Intrauterine Device is Effective as Emergency Contraception

, 2021
Emergency contraception prevents pregnancy after sexual intercourse. The FDA has approved two "morning-after" pills for this purpose, and the copper intrauterine device (IUD) is an order of magnitude more effective than these oral options.
Turok, D.; Simmons, R.; Kaiser, J.; Gawron, L.; Sanders, J.
core  

Acne resolution rates: Results of a single-blind, randomized, controlled, parallel phase III trial with EE/CMA (Belara (R)) and EE/LNG (Microgynon (R)) [PDF]

, 2001
Background and Objective: Acne in women can often be successfully treated by the intake of oral contraceptives containing gestagens with anti-androgenic properties.
Zahradnik, H. P., Arp, W., Andreas, J. O., Binder, N., Worret, I.   +4 more
core   +1 more source