Results 101 to 110 of about 12,531 (249)

Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? [PDF]

, 2018
Aims: Changes in systolic blood pressure (SBP) during an admission for acute heart failure (AHF), especially those leading to hypotension, have been suggested to increase the risk for adverse outcomes.
Bourge, Robert C., Cleland, John G.F., Cotter, Gad, Davison, Beth A., Edwards, Christopher, Jondeau, Guillaume, Kobrin, Isaac, McMurray, John J.V., Metra, Marco, Milo, Olga, O'Connor, Christopher M., Parker, John D., Rainisio, Maurizio, Senger, Stefanie, Teerlink, John R., Torre-Amione, Guillermo, van Veldhuisen, Dirk J.   +16 more
core   +3 more sources

Levosimendan as rescue therapy in low output syndrome after cardiac surgery: effects and predictors of outcome

Journal of International Medical Research, 2019
Objectives Calcium sensitizers have been shown to improve outcomes in patients with low cardiac output syndrome (LCOS) after cardiac surgery. We assessed the effects of levosimendan on LCOS in cardiac surgical patients to identify outcome predictors ...
Andres Beiras-Fernandez, Angela Kornberger, Martin Oberhoffer, Felix Kur, Marion Weis, Christian-Friedrich Vahl, Florian Weis   +6 more
doaj   +1 more source

Levosimendan does not reduce the mortality of critically ill adult patients with sepsis and septic shock: a meta-analysis

Chinese Medical Journal, 2019
. Background:. Previous studies on whether or not levosimendan improved the prognosis of patients with sepsis and septic shock have been inconsistent. We aimed to provide an updated analysis of the therapeutic value of levosimendan in adult patients with
Fang Feng, Yu Chen, Min Li, Jiao-Jiao Yuan, Xue-Ni Chang, Chen-Ming Dong, Li-Min Chen   +6 more
doaj   +1 more source

Pantethine therapy dramatically rescues end‐stage failing heart in a patient with deficiency of coenzyme A biosynthesis

ESC Heart Failure, Volume 12, Issue 4, Page 3195-3199, August 2025.
Violette Goetz, Bruno Lefort, Magalie Barth, Naïg Gueguen, Céline Bris, Emmanuelle Blanchard, Isabelle Benz‐de Bretagne, Hélène Blasco, Marine Tardieu, François Labarthe   +9 more
wiley   +1 more source

Muscle Fatigue from the Perspective of a Single Crossbridge [PDF]

, 2016
The repeated intense stimulation of skeletal muscle rapidly decreases its force- and motion-generating capacity. This type of fatigue can be temporally correlated with the accumulation of metabolic by-products, including phosphate (Pi) and protons (H ...
Debold, Edward Patrick, Fitts, Robert H., Nosek, Thomas M., Sundberg, Christopher W.   +3 more
core   +1 more source

Manejo del bajo gasto cardíaco en el posoperatorio cardiovascular pediátrico [PDF]

, 2010
Fil: Grzona, María Estela. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas.
Grzona, María Estela
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An In Vitro Investigation of the Antiproliferative and Antimetastatic Effects of Levosimendan: Potential Drug Repurposing for Cervical Cancer

Current Issues in Molecular Biology
Cervical cancer presents a significant challenge to the global health of women. Despite substantial advances in human papillomavirus (HPV)-related cervical cancer vaccines, non-HPV-related cervical cancer is still waiting novel therapeutic options.
Zsuzsanna Schelz, Hiba F. Muddather, Fatemeh Sheihaki Jaski, Noémi Bózsity, István Zupkó   +4 more
doaj   +1 more source

Transdermal delivery of levosimendan

European Journal of Pharmaceutical Sciences, 2000
The aim of this study was to determine if transdermal penetration of levosimendan, a novel positive inotropic drug, could be enhanced and controlled by formulation modifications. Penetration of levosimendan across human epidermis in vitro was determined using abdominal excised skin and diffusion cells.
R, Valjakka-Koskela, J, Hirvonen, J, Mönkkönen, J, Kiesvaara, S, Antila, L, Lehtonen, A, Urtti   +6 more
openaire   +2 more sources

The effects of levosimendan use on high-sensitivity C-reactive protein in patients with decompensated heart failure [PDF]

, 2019
Hasan Korkmaz, Mücahid Yılmaz
openalex   +1 more source

Investigations for the mechanism of action of novel positive inotropic agents [PDF]

, 2017
Az akut szívelégtelenség mortalitása a fejlődő farmakológiai és eszközös kezelés ellenére magas, sőt a Ca2+-mobilizáló inotróp szerek adverz hatásúak a hosszú távú túlélésre.
Nagy, László
core