Results 111 to 120 of about 12,502 (244)

Kidney injury in patients with heart failure‐related cardiogenic shock: Results from an international, multicentre cohort study

European Journal of Heart Failure, Volume 27, Issue 11, Page 2397-2409, November 2025.
Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.
Jonas Sundermeyer, Caroline Kellner, Benedikt N. Beer, Lisa Besch, Angela Dettling, Letizia Fausta Bertoldi, Stefan Blankenberg, Jeroen Dauw, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Joanna Jozwiak‐Nozdrzykowska, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Enzo Lüsebrink, Nicolas Majunke, Norman Mangner, Sven Möbius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, P. Christian Schulze, Robert H.G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Ephraim B. Winzer, Dirk Westermann, Benedikt Schrage   +41 more
wiley   +1 more source

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. [PDF]

, 2017
OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012." DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened.
Alhazzani, W, Angus, DC, Annane, D, Antonelli, M, Beale, RJ, Bellinghan, GJ, Bernard, GR, Chiche, J-D, Coopersmith, C, De Backer, DP, Dellinger, RP, Evans, LE, Ferrer, R, French, CJ, Fujishima, S, Gerlach, H, Hidalgo, JL, Hollenberg, SM, Jones, AE, Karnad, DR, Kleinpell, RM, Koh, Y, Kumar, A, Levy, MM, Lisboa, TC, Machado, FR, Marini, JJ, Marshall, JC, Mazuski, JE, McIntyre, LA, McLean, AS, Mehta, S, Moreno, RP, Myburgh, J, Navalesi, P, Nishida, O, Nunnally, ME, Osborn, TM, Perner, A, Plunkett, CM, Ranieri, M, Rhodes, A, Rochwerg, B, Rubenfeld, GD, Schorr, CA, Seckel, MA, Sevransky, JE, Seymour, CW, Shieh, L, Shukri, KA, Simpson, SQ, Singer, M, Sprung, CL, Thompson, BT, Townsend, SR, Van der Poll, T, Vincent, J-L, Wiersinga, WJ, Zimmerman, JL   +58 more
core   +5 more sources

The therapeutic effect of levosimendan in patients with prolonged ventilator weaning and cardiac dysfunction

Journal of International Medical Research
Objective To explore the therapeutic effect of levosimendan in patients with prolonged ventilator weaning and cardiac dysfunction. Method Patients with prolonged ventilator weaning and cardiac dysfunction were randomly allocated to receive conventional ...
Fang Xiong, Zongjun Hu, Chao Liu, Kexiang Zhang, Qilong Zhou, Jianguo Chen, Hua Lu, Xi Yue, Jianxin Zhao, Pengfei Pan   +9 more
doaj   +1 more source

Dopamine is associated with the worst outcome among inotropes used in acute heart failure: observations from the ESC-HF-LT registry [PDF]

, 2017
Abstrac
Akiyama, Eiichi, Chioncel, Ovidiu, Crespo-Leiro, María Generosa, Filippatos, Gerasimos, Gayat, Etienne, Lund, Lars H., Maggioni, Aldo P., Mebazaa, Alexandre, Motiejunaite, J., Ruschitzka, Frank   +9 more
core   +2 more sources

Initial clinical experience with dapagliflozin in addition to optimized medical therapy in paediatric heart failure patients

ESC Heart Failure, Volume 12, Issue 5, Page 3494-3501, October 2025.
Abstract Aims Dapagliflozin, a sodium‐glucose cotransporter 2 (SGLT2) inhibitor, has shown clinical benefits in adults with heart failure (HF), improving cardiac function, reducing HF‐related hospitalizations and enhancing survival rates. While extensively studied in adult HF, data on its efficacy and safety in paediatric HF patients remain limited. We
Lisa‐Maria Rosenthal, Oliver Miera, Annemarie Krauss, Friederike Danne, Felix Berger, Peter Kramer   +5 more
wiley   +1 more source

Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT

Efficacy and Mechanism Evaluation, 2018
Background: In septic shock, cardiovascular resuscitation using catecholamine vasopressors and inotropes is standard therapy, but catecholamines have important side effects.
Anthony C Gordon, Shalini Santhakumaran, Farah Al-Beidh, Robert ML Orme, Gavin D Perkins, Mervyn Singer, Daniel F McAuley, Alexina J Mason, Josie K Ward, Kieran P O’Dea, Timothy Felton, Mary Cross, Janis Best-Lane, Jonas Lexow, Ashley Campbell, Deborah Ashby   +15 more
doaj   +1 more source

Pro‐ and Anti‐Inflammatory Responses and Clinical Outcomes in Critically Ill Patients With Endotheliopathy: A Cohort Study

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 9, October 2025.
ABSTRACT Background Multiple organ dysfunction syndrome (MODS) in critical illness involves dysregulated immune and inflammatory responses, endotheliopathy, and coagulation activation. We investigated how three types of endotheliopathy biomarkers relate to pro‐ and anti‐inflammatory responses and clinical outcomes in intensive care unit (ICU) patients.
Caroline Humble, Martin Schønemann‐Lund, Peter Bruun‐Rasmussen, Morten H. Bestle, Pär I. Johansson, Lone M. Poulsen, Ole Mathiesen   +6 more
wiley   +1 more source

ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]

, 2015
Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md, Bayes, Genis, DI SOMMA, Salvatore, Maisel, Alan S., Md,, Md,, Md,, Mebazaa, Alexandre   +7 more
core   +1 more source

Old and new intravenous inotropic agents in the treatment of advanced heart failure [PDF]

, 2011
Inotropic agents are administered to improve cardiac output and peripheral perfusion in patients with systolic dysfunction and low cardiac output. However, there is evidence of increased mortality and adverse effects associated with current inotropic ...
Bettari L, Carubelli V, Dei Cas L., Metra M   +3 more
core   +1 more source

Levosimendan in Cardiac Surgery

Journal of Cardiothoracic and Vascular Anesthesia, 2005
Levosimendan is a new calcium sensitizer with inodilatory properties. There is growing clinical experience with levosimendan given to cardiac surgical patients. The aim of this report was to evaluate the effects of perioperative use of levosimendan in surgical patients with high perioperative risk, compromised left ventricular (LV) function, or ...
Harjola, V, Siirilä, K, Suojaranta-Ylinen, R   +2 more
openaire   +2 more sources