Results 71 to 80 of about 12,531 (249)

Kidney injury in patients with heart failure‐related cardiogenic shock: Results from an international, multicentre cohort study

European Journal of Heart Failure, Volume 27, Issue 11, Page 2397-2409, November 2025.
Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.
Jonas Sundermeyer, Caroline Kellner, Benedikt N. Beer, Lisa Besch, Angela Dettling, Letizia Fausta Bertoldi, Stefan Blankenberg, Jeroen Dauw, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Joanna Jozwiak‐Nozdrzykowska, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Enzo Lüsebrink, Nicolas Majunke, Norman Mangner, Sven Möbius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, P. Christian Schulze, Robert H.G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Ephraim B. Winzer, Dirk Westermann, Benedikt Schrage   +41 more
wiley   +1 more source

Predictivity of in vitro non-clinical cardiac contractility assays for inotropic effects in humans – A Literature Search [PDF]

, 2015
Adverse drug effects on the cardiovascular system is a major cause of compound attrition throughout compound discovery and development. There are many ways by which drugs can affect the cardiovascular system, including effects on the electrocardiogram ...
Gharanei, Mayel, Maddock, Helen L., Wallis, R.   +2 more
core   +1 more source

İleri kalp yetersizliği hastalarında levosimendanın eritrosit dağılım genişliği üzerine etkisi

Genel Tıp Dergisi, 2015
Amaç: Levosimendan dekompanse kalp yetersizliğinde kullanılan, olumlu hemodinamik etkileri de olan pozitif inotropik bir ilaçtır. Bu çalışmanın amacı levosimendan tedavisi almış ileri kalp yetersizliği hastalarının tedavi öncesi ve sonrası eritrosit ...
Ahmet Gürel, Niyazi Güler, Murat Aydın, Şeref Alpsoy, Aydın Akyüz, Dursun Çayan Akkoyun   +5 more
doaj  

Prophylactic use of levosimendan in pediatric patients undergoing cardiac surgery: a prospective randomized controlled trial

Critical Care, 2019
Background The administration of levosimendan prophylactically to patients undergoing cardiac surgery remains a controversial practice, and few studies have specifically assessed the value of this approach in pediatric patients.
Anbiao Wang, Chaomei Cui, Yiou Fan, Jie Zi, Jie Zhang, Guanglai Wang, Fang Wang, Jun Wang, Qi Tan   +8 more
doaj   +1 more source

Initial clinical experience with dapagliflozin in addition to optimized medical therapy in paediatric heart failure patients

ESC Heart Failure, Volume 12, Issue 5, Page 3494-3501, October 2025.
Abstract Aims Dapagliflozin, a sodium‐glucose cotransporter 2 (SGLT2) inhibitor, has shown clinical benefits in adults with heart failure (HF), improving cardiac function, reducing HF‐related hospitalizations and enhancing survival rates. While extensively studied in adult HF, data on its efficacy and safety in paediatric HF patients remain limited. We
Lisa‐Maria Rosenthal, Oliver Miera, Annemarie Krauss, Friederike Danne, Felix Berger, Peter Kramer   +5 more
wiley   +1 more source

Long‐term safety of intravenous cardiovascular agents in acute heart failure: results from the European Society of Cardiology Heart Failure Long‐Term Registry [PDF]

, 2017
[Abstract] Aims. The aim of this study was to assess long‐term safety of intravenous cardiovascular agents—vasodilators, inotropes and/or vasopressors—in acute heart failure (AHF). Methods and results.
Aldo P. Maggioni, Alexandre Mebazaa, Cecile Laroche, Eiichi Akiyama, Etienne Gayat, Eulalia Roig, Frank Ruschitzka, Gerasimos Filippatos, Justina Motiejunaite, Lars H. Lund, Maria G. Crespo-Leiro, Marisa Sanz Julve, null null, Ovidiu Chioncel, Petar Seferovic, Veli-Pekka Harjola   +15 more
core   +2 more sources

Pro‐ and Anti‐Inflammatory Responses and Clinical Outcomes in Critically Ill Patients With Endotheliopathy: A Cohort Study

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 9, October 2025.
ABSTRACT Background Multiple organ dysfunction syndrome (MODS) in critical illness involves dysregulated immune and inflammatory responses, endotheliopathy, and coagulation activation. We investigated how three types of endotheliopathy biomarkers relate to pro‐ and anti‐inflammatory responses and clinical outcomes in intensive care unit (ICU) patients.
Caroline Humble, Martin Schønemann‐Lund, Peter Bruun‐Rasmussen, Morten H. Bestle, Pär I. Johansson, Lone M. Poulsen, Ole Mathiesen   +6 more
wiley   +1 more source

The therapeutic effect of levosimendan in patients with prolonged ventilator weaning and cardiac dysfunction

Journal of International Medical Research
Objective To explore the therapeutic effect of levosimendan in patients with prolonged ventilator weaning and cardiac dysfunction. Method Patients with prolonged ventilator weaning and cardiac dysfunction were randomly allocated to receive conventional ...
Fang Xiong, Zongjun Hu, Chao Liu, Kexiang Zhang, Qilong Zhou, Jianguo Chen, Hua Lu, Xi Yue, Jianxin Zhao, Pengfei Pan   +9 more
doaj   +1 more source

Intermittent inotropic therapy with levosimendan vs. milrinone in advanced heart failure patients

ESC Heart Failure, 2022
Aims Routine, intermittent inotropic therapy (IIT) is still applied in advanced heart failure (HF) patients either as a bridge to definitive treatment or as a mean to improve quality of life (QOL), despite limited evidence to support its' use.
Assi Milwidsky, Shir Frydman, Michal Laufer‐Perl, Ben Sadeh, Orly Sapir, Yoav Granot, Aviram Hochstadt, Liuba Korotetski, Liora Ketchker, Yan Topilsky, Shmuel Banai, Ofer Havakuk   +11 more
doaj   +1 more source

ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]

, 2015
Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md, Bayes, Genis, DI SOMMA, Salvatore, Maisel, Alan S., Md,, Md,, Md,, Mebazaa, Alexandre   +7 more
core   +1 more source