Results 71 to 80 of about 6,081 (225)

SGLT‐2 inhibitors for cardiac amyloidosis: Hype or hope?

European Journal of Clinical Investigation, Volume 55, Issue 11, November 2025.
Flavio Tangianu, Eleonora Nicolini, Francesco Dentali, Aldo Bonaventura   +3 more
wiley   +1 more source

Multivariable Modeling of Postoperative Risk in Infant Cardiac Surgery: Integrating Clinical Variables and 20 Inflammatory Biomarkers

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
ABSTRACT Introduction Cardiac surgery in infants often triggers a severe inflammatory response. The role of biomarkers in predicting clinical outcomes in this group of patients has been debated in the literature. This study aimed to investigate the predictive value of 20 inflammatory biomarkers, in combination with clinical data, for acute kidney ...
Rúnar Bragi Kvaran, Andreas Skagervik, Fredrik Pernbro, Birgitta Romlin, Mattias Molin, Håkan Wåhlander, Hans Christian D. Aass, Maria Vistnes, Tiina Ojala, Elin M. Thorlacius, Albert Gyllencreutz Castellheim   +10 more
wiley   +1 more source

Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT

Efficacy and Mechanism Evaluation, 2018
Background: In septic shock, cardiovascular resuscitation using catecholamine vasopressors and inotropes is standard therapy, but catecholamines have important side effects.
Anthony C Gordon, Shalini Santhakumaran, Farah Al-Beidh, Robert ML Orme, Gavin D Perkins, Mervyn Singer, Daniel F McAuley, Alexina J Mason, Josie K Ward, Kieran P O’Dea, Timothy Felton, Mary Cross, Janis Best-Lane, Jonas Lexow, Ashley Campbell, Deborah Ashby   +15 more
doaj   +1 more source

Levosimendan in Regional Myocardial Ischemia

Cardiovascular Drugs and Therapy, 2002
Levosimendan is a new positive inotropic agent with anxillary vasodilating effects. It increases heart rate, stroke volume, and cardiac output and decreases systemic, pulmonary and coronary artery vascular resistance as well as filling pressures [1]. Its mode of action is believed to involve a unique calcium sensitizing effect: it binds to Troponin C ...
openaire   +4 more sources

Clinical profile, short and long‐term outcomes of non‐ischaemic cardiogenic shock: A FRENSHOCK sub‐analysis

ESC Heart Failure, Volume 12, Issue 3, Page 2335-2346, June 2025.
Abstract Aims Although predominant in routine practice, non‐ischaemic cardiogenic shock (NICS) remains underrepresented in past studies, mainly focused on ischaemic cardiogenic shock (CS). This study aims to describe the current NICS picture and define its independent correlates of short‐ and long‐term outcomes.
Miloud Cherbi, François Roubille, Edouard Gerbaud, Eric Bonnefoy, Nicolas Lamblin, Laurent Bonello, Bruno Levy, Pascal Lim, Hamid Merdji, Meyer Elbaz, Hadi Khachab, Jeremy Bourenne, Marie‐France Seronde, Guillaume Schurtz, Brahim Harbaoui, Gerald Vanzetto, Nicolas Combaret, Benoit Lattuca, Guillaume Leurent, Etienne Puymirat, Clément Delmas   +20 more
wiley   +1 more source

Bibliometric analysis of levosimendan

IJC Heart & Vasculature
BACKGROUND: Levosimendan (LEVO), a calcium sensitizer and adenosine triphosphate-dependent potassium channel opener, has been widely used for decades in medical and surgical patients for advanced heart failure (HF), right ventricular failure, cardiogenic shock, takotsubo cardiomyopathy, pulmonary hypertension, and so on. Currently, as the limited scope
Xian-Shu Zhao, Yi-Ping Yu, Yun-Tai Yao
openaire   +2 more sources

Long‐term outcomes of electrical storm patients listed for urgent heart transplantation but not transplanted acutely

ESC Heart Failure, Volume 12, Issue 3, Page 1583-1593, June 2025.
Abstract Aims Refractory electrical storm (ES) is a life‐threatening condition in which heart transplantation (HTx) can be proposed. Nevertheless, the shortage of donors and subsequent outcomes question its place as a rescue strategy. We aim to describe the prognosis of ES patients listed for HTx but not transplanted.
Miloud Cherbi, Philippe Maury, Léa Benabou, Maxime Faure, Matteo Pozzi, Laurent Sebbag, Estelle Gandjbakhch, Karim Benali, Pierre Groussin, Redwane Rakza, Raphael P. Martins, Clément Delmas   +11 more
wiley   +1 more source

Levosimendan in Cardiac Surgery [PDF]

New England Journal of Medicine, 2017
Landoni G, Lomivorotov VV, Bellomo R.
openaire   +8 more sources

Pantethine therapy dramatically rescues end‐stage failing heart in a patient with deficiency of coenzyme A biosynthesis

ESC Heart Failure, Volume 12, Issue 4, Page 3195-3199, August 2025.
Violette Goetz, Bruno Lefort, Magalie Barth, Naïg Gueguen, Céline Bris, Emmanuelle Blanchard, Isabelle Benz‐de Bretagne, Hélène Blasco, Marine Tardieu, François Labarthe   +9 more
wiley   +1 more source

Levosimendan as rescue therapy in low output syndrome after cardiac surgery: effects and predictors of outcome

Journal of International Medical Research, 2019
Objectives Calcium sensitizers have been shown to improve outcomes in patients with low cardiac output syndrome (LCOS) after cardiac surgery. We assessed the effects of levosimendan on LCOS in cardiac surgical patients to identify outcome predictors ...
Andres Beiras-Fernandez, Angela Kornberger, Martin Oberhoffer, Felix Kur, Marion Weis, Christian-Friedrich Vahl, Florian Weis   +6 more
doaj   +1 more source