Results 21 to 30 of about 51,650 (294)

Medications and Food Interfering with the Bioavailability of Levothyroxine: A Systematic Review

open access: yesTherapeutics and Clinical Risk Management, 2023
Purpose Levothyroxine is a common prescribed drug. Many medications and food, however, can interfere with its bioavailability. The aim of this review was to summarize the medications, food and beverages that interact with levothyroxine and to assess ...
Hanqing Liu   +6 more
semanticscholar   +1 more source

The enigma of persistent symptoms in hypothyroid patients treated with levothyroxine: A narrative review

open access: yesClinical Endocrinology, 2021
A significant minority of patients with hypothyroidism report persistent symptoms despite achieving normal thyroid biochemistry after levothyroxine (L‐T4) replacement.
P. Perros   +5 more
semanticscholar   +1 more source

Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document

open access: yesEuropean Thyroid Journal, 2020
Background: Fourteen clinical trials have not shown a consistent benefit of combination therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these trials, combination therapy is widely used and patients reporting benefit ...
J. Jonklaas   +11 more
semanticscholar   +1 more source

Effect of Levothyroxine on Older Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Endocrinology, 2022
Background Subclinical hypothyroidism (SCH) is usually treated with levothyroxine, but there is controversy as to whether SCH should be treated, especially for older patients.
Chunyan Zhao   +3 more
semanticscholar   +1 more source

Levothyroxine Interactions with Food and Dietary Supplements–A Systematic Review

open access: yesPharmaceuticals, 2021
Levothyroxine (l-thyroxine, l-T4) is a drug of choice for treating congenital and primary hypothyroidism. Although clinically significant interactions between l-T4 and food can alter the safety and efficacy of the treatment, they still seem to be ...
A. Wiesner, D. Gajewska, P. Paśko
semanticscholar   +1 more source

Levothyroxine Timing during Ramadan: A Randomized Clinical Trial

open access: yesInternational Journal of Endocrinology, 2023
Introduction. Hypothyroidism requires lifelong thyroid hormone replacement with levothyroxine. For most hypothyroid patients fasting during Ramadan, compliance with the administration procedure is a challenge.
Moeber Mahzari   +7 more
doaj   +1 more source

Use of levothyroxine in the management of hypothyroidism: A historical perspective

open access: yesFrontiers in Endocrinology, 2022
The thyroid operates within a complex system of homeostatic regulation, where the level of thyrotropin (TSH) influences the rate of secretion of the principal thyroid hormones, thyroxine (T4) and triiodothyronine (T3).
G. Kahaly, Ulrike Gottwald-Hostalek
semanticscholar   +1 more source

Prevalence and factors associated with chronic use of levothyroxine: A cohort study.

open access: yesPLoS ONE, 2021
ImportanceLevothyroxine prescriptions are rising worldwide. However, there are few data on factors associated with chronic use.ObjectiveTo assess the prevalence of chronic levothyroxine use, its rank among other chronic drugs and factors associated with ...
Camilla Janett-Pellegri   +10 more
doaj   +1 more source

Levothyroxine Therapy in Elderly Patients With Hypothyroidism

open access: yesFrontiers in Endocrinology, 2021
Levothyroxine (L-T4) treatment of overt hypothyroidism can be more challenging in elderly compared to young patients. The elderly population is growing, and increasing incidence and prevalence of hypothyroidism with age are observed globally.
G. Effraimidis   +2 more
semanticscholar   +1 more source

Investigating the Effect of Genetic Polymorphisms of Deiodinase Type 2 on Levothyroxine Dose Requirements in Patients with Hypothyroidism

open access: yesمجله كليه طب الكندي, 2023
Background: Hypothyroidism is the most abundant thyroid disorder worldwide. For decades, levothyroxine was the main effective pharmacological treatment for hypothyroidism. A variety of factors can influence levothyroxine dose, such as genetic variations.
Nada Hamid Rasheed   +2 more
doaj   +1 more source

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