Results 51 to 60 of about 36,523 (215)

Changes in Serum TSH and T4 Levels after Switching the Levothyroxine Administration Time from before Breakfast to before Dinner

International Journal of Endocrinology, 2015
Background. Levothyroxine is commonly used in the treatment of patients with hypothyroidism. Levothyroxine is most often administered in the morning, on an empty stomach, in order to increase its oral absorption.
S. Ala, O. Akha, Z. Kashi, A. Bahar, H. Askari Rad, N. Sasanpour, A. Shiva   +6 more
doaj   +1 more source

Effect of oral semaglutide on the pharmacokinetics of thyroxine after dosing of levothyroxine and the influence of co-administered tablets on the pharmacokinetics of oral semaglutide in healthy subjects: an open-label, one-sequence crossover, single-center, multiple-dose, two-part trial

Expert Opinion on Drug Metabolism & Toxicology, 2021
Background Oral semaglutide comprises the glucagon-like peptide-1 analog, semaglutide, and sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). Levothyroxine has similar dosing conditions to oral semaglutide.
Camilla Hauge, Astrid Breitschaft, M. Hartoft‐Nielsen, S. Jensen, T. Bækdal   +4 more
semanticscholar   +1 more source

Risk of cancer in long‐term levothyroxine users: Retrospective population‐based study

Cancer Science, 2021
Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. The relationship between levothyroxine use and cancer risk is largely underdetermined.
Chieh-Chen Wu, Mohaimenul Islam, P. Nguyen, T. N. Poly, Ching-Huan Wang, Usman Iqbal, Y. Li, Hsuan-Chia Yang   +7 more
semanticscholar   +1 more source

Levothyroxine use and the risk of colorectal cancer: a large population-based case–control study

Endocrine Connections, 2022
Objective: Whether an association between oral levothyroxine use, leading to supraphysiological exposure of the colon to thyroid hormones, and risk of colorectal cancer exists in humans is unclear.
Josephina G Kuiper, Aline C Fenneman, Anne H van der Spek, Elena Rampanelli, Max Nieuwdorp, Myrthe P P van Herk-Sukel, Valery E P P Lemmens, Ernst J Kuipers, Ron M C Herings, Eric Fliers   +9 more
doaj   +1 more source

Impact of levothyroxine in women with positive thyroid antibodies on pregnancy outcomes: a systematic review and meta-analysis of randomised controlled trials

BMJ Open, 2021
Objective To evaluate the effect of levothyroxine therapy on pregnancy outcomes compared with placebo or no treatment in women without overt hypothyroidism with presence of thyroid peroxidase antibodies (TPOAb) and/or thyroglobulin antibodies (TgAb ...
Lorraine Lau, J. Benham, Patricia Lemieux, J. Yamamoto, L. Donovan   +4 more
semanticscholar   +1 more source

The Effects of Simvastatin on the Serum Concentrations of Thyroid Stimulating Hormone and Free Thyroxine in Hypothyroid Patients Treated with Levothyroxine [PDF]

Iranian Journal of Medical Sciences, 2011
Background: Statins, such as simvastatin, are the drugs of choice for the treatment of hypercholesterolemia. On the other hand hypercholesterolmia can occur in hypothyroid patients, who receive levothyroxine.
Mohammad Abbasinazari, Manouchehr Nakhjavani, Sima Gogani   +2 more
doaj  

Risk of All-Cause Mortality in Levothyroxine-Treated Hypothyroid Patients: A Nationwide Korean Cohort Study

Frontiers in Endocrinology, 2021
Background Although hypothyroidism is associated with various comorbidities, its relationship with increased all-cause mortality remains controversial. The aim of this nationwide retrospective cohort study was to investigate whether hypothyroid patients ...
S. Sohn, G. Seo, J. Chung
semanticscholar   +1 more source

Evaluation of Thyroid Hormone Status: Are Simultaneous TSH and FT4 Tests Necessary? Analysis of Thyroid Function Test Results Taken From the Greater Manchester Care Record 2010-2023. [PDF]

Clin Endocrinol (Oxf)
Clinical Endocrinology, Volume 103, Issue 6, Page 906-908, December 2025.
Stedman M, Taylor P, Halsall I, Halsall D, Okosieme B, Bahl S, Premawardhana L, Dayan C, Fryer AA, Heald A.   +9 more
europepmc   +2 more sources

Van Wyk-Grumbach Syndrome With Insulin Resistance in Children: A Case Report. [PDF]

Clin Case Rep
Brain magnetic resonance imaging (MRI) at diagnosis and after 3 months of levothyroxine replacement. ABSTRACT This case reports an 8 year‐5 month‐old girl diagnosed with Van Wyk–Grumbach Syndrome (VWGS) and co‐existing insulin resistance from China. The patient achieved complete resolution of clinical manifestations with thyroid hormone replacement ...
Liu H, Liu G, Wang H, Suo W, Wang Y, Ding H.   +5 more
europepmc   +2 more sources

Treatment of congenital hypothyroidism in  a  newborn with malabsorption after subtotal ileum resection

Endocrinology, Diabetes & Metabolism Case Reports, 2018
Congenital hypothyroidism requires prompt treatment to prevent adverse health outcomes. Poor intestinal levothyroxine absorption can complicate management. We present a case of a term female newborn with necrotizing enterocolitis (NEC) requiring subtotal
Charlotte S Schömig, Marie-Ève Robinson, Julia E von Oettingen   +2 more
doaj   +1 more source