Frontiers in Endocrinology, 2021 Background The cardiovascular effects of treating older adults with subclinical hypothyroidism (SCH) are uncertain. Although concerns have been raised regarding a potential increase in cardiovascular side effects from thyroid hormone replacement ...
Laurien E. Zijlstra +17 more
semanticscholar +1 more source
Levothyroxine use and the risk of colorectal cancer: a large population-based case–control study
Endocrine Connections, 2022 Objective: Whether an association between oral levothyroxine use, leading to supraphysiological exposure of the colon to thyroid hormones, and risk of colorectal cancer exists in humans is unclear.
Josephina G Kuiper +9 more
doaj +1 more source
The Clinical Significance of Subclinical Thyroid Dysfunction. [PDF]
, 2008 Subclinical thyroid disease (SCTD) is defined as serum free T(4) and free T(3) levels within their respective reference ranges in the presence of abnormal serum TSH levels.
BIONDI, BERNADETTE, COOPER DS
core +1 more source
Thyroid hormone therapy for older adults with subclinical hypothyroidism [PDF]
, 2017 The Authors ...
Bauer, Douglas C. +2 more
core +2 more sources
A hidden cause of infertility in hypothyroid patients [PDF]
, 2020 Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy +4 more
core +1 more source
Thyroid, 2021 Background: Combined therapy with levothyroxine (LT4)/L-triiodothyronine (LT3) has garnered attention among clinicians and patients as a potential treatment alternative to LT4 monotherapy. The objective of this study was to compare the benefits and harms
J. M. Millán-Alanís +8 more
semanticscholar +1 more source
Study protocol; thyroid hormone replacement for untreated older adults with subclinical hypothyroidism - a randomised placebo controlled trial (TRUST) [PDF]
, 2017 Background: Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4).
Bauer, Douglas +24 more
core +12 more sources
The Effects of Simvastatin on the Serum Concentrations of Thyroid Stimulating Hormone and Free Thyroxine in Hypothyroid Patients Treated with Levothyroxine [PDF]
Iranian Journal of Medical Sciences, 2011 Background: Statins, such as simvastatin, are the drugs of choice for the treatment of hypercholesterolemia. On the other hand hypercholesterolmia can occur in hypothyroid patients, who receive levothyroxine.
Mohammad Abbasinazari +2 more
doaj
Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over [PDF]
, 2018 Background: Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of subclinical hypothyroidism in persons aged 80 ...
Blum, M.R. +20 more
core +8 more sources
Recent advances in managing differentiated thyroid cancer [PDF]
, 2018 The main clinical challenge in the management of thyroid cancer is to avoid over-treatment and over-diagnosis in patients with lower-risk disease while promptly identifying those patients with more advanced or high-risk disease requiring aggressive ...
Durante, Cosimo +3 more
core +2 more sources