The Interplay Between CA19-9 and the Lewis Blood Group System: Implications for the Diagnosis of Gallbladder Cancer. [PDF]
Liu Y +6 more
europepmc +1 more source
Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao +12 more
wiley +1 more source
Host range and zoonotic potential linked to P-like fimbrial (PLF) adhesin specificity in avian pathogenic Escherichia coli. [PDF]
Akrami F +5 more
europepmc +1 more source
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
ABSTRACT Objectives Both psychosocial stress and current infection can increase the likelihood of reactivation of latent Epstein–Barr virus (EBV). Pregnancy and infection with SARS‐CoV‐2 can be stressful and modulate immune function. However, it is unknown how SARS‐CoV‐2 infection and stress further interact among postpartum women to affect EBV antigen
Emma Anastasi +18 more
wiley +1 more source
Therapeutic targeting of cancer stem cell-specific surface glycans and glycoproteins. [PDF]
Al-Khreisat MJ +8 more
europepmc +1 more source
Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression
Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik +4 more
wiley +1 more source
Subunit vaccination using Atomic Layering Thermostable Antigen and Adjuvant (ALTA<sup>®</sup>) platform elicits enhanced humoral and cellular immune responses. [PDF]
Ivanova DL +12 more
europepmc +1 more source
NSCLC contains an MHC‐II‐associated antigen‐presenting CAF‐like (apCAF‐like) state regulated by the NRF2‐KPNB1 axis. NRF2/KPNB1 signaling suppresses CIITA‐dependent antigen presentation and T‐cell activation, whereas inhibition of this pathway enhances antitumor immunity and improves responsiveness to anti‐PD‐1 therapy.
Fei Zheng +5 more
wiley +1 more source

